Project name: 8c375758350b4ac

Chain sequence(s)	A: FEFEFEGSKGH; C: FEFEFEGSKGH; B: FEFEFEGSKGH; E: FEFEFEGSKGH; D: FEFEFEGSKGH; G: FEFEFEGSKGH; F: FEFEFEGSKGH; H: FEFEFEGSKGH
Selected Chain(s)	A,C,B,E,D,G,F,H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:17)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:20)

• Minimal score value: -4.2129
• Maximal score value: 0.8704
• Average score: -1.9881
• Total score value: -174.955

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	-0.9946
2	E	A	-2.9182
3	F	A	0.0000
4	E	A	-3.5574
5	F	A	0.0000
6	E	A	-4.0512
7	G	A	-2.9681
8	S	A	-2.7679
9	K	A	0.0000
10	G	A	-1.9695
11	H	A	-1.4664
1	F	B	-1.6406
2	E	B	-3.2466
3	F	B	0.0000
4	E	B	-3.6265
5	F	B	0.0000
6	E	B	-4.0421
7	G	B	-2.9265
8	S	B	-2.7185
9	K	B	0.0000
10	G	B	-1.6629
11	H	B	-1.0409
1	F	C	0.8704
2	E	C	-1.7002
3	F	C	-1.4978
4	E	C	-3.0391
5	F	C	-2.2466
6	E	C	-3.3622
7	G	C	-1.9976
8	S	C	-2.2791
9	K	C	-2.4116
10	G	C	-2.3411
11	H	C	-1.8619
1	F	D	0.2100
2	E	D	-1.9660
3	F	D	-1.5265
4	E	D	-2.9590
5	F	D	-2.2754
6	E	D	-3.3958
7	G	D	-2.3242
8	S	D	-2.5577
9	K	D	-3.0101
10	G	D	-2.4751
11	H	D	-1.9140
1	F	E	-1.4476
2	E	E	-3.2254
3	F	E	0.0000
4	E	E	-3.6662
5	F	E	0.0000
6	E	E	-4.1519
7	G	E	-2.9968
8	S	E	-2.7183
9	K	E	0.0000
10	G	E	-1.8372
11	H	E	-1.2968
1	F	F	-1.2136
2	E	F	-2.9990
3	F	F	0.0000
4	E	F	-3.5826
5	F	F	0.0000
6	E	F	-4.2129
7	G	F	-3.0100
8	S	F	-2.7231
9	K	F	0.0000
10	G	F	-1.8881
11	H	F	-1.3804
1	F	G	0.0705
2	E	G	-1.9884
3	F	G	-1.5276
4	E	G	-2.9828
5	F	G	-2.3036
6	E	G	-3.4213
7	G	G	-2.1921
8	S	G	-2.3035
9	K	G	-2.4607
10	G	G	-2.1833
11	H	G	-1.7502
1	F	H	0.3962
2	E	H	-1.9205
3	F	H	-1.4906
4	E	H	-2.9853
5	F	H	-2.2393
6	E	H	-3.3511
7	G	H	-2.1628
8	S	H	-2.2364
9	K	H	-2.3099
10	G	H	-2.0707
11	H	H	-1.5332