| Chain sequence(s) |
A: MNNHVSSKPSTMKLKHTINPILLYFIHFLISLYTILTYIPFYFFSESRQEKSNRIKAKPVNSKPDSAYRSVNSLDGLASVLYPGCDTLDKVFTYAKNKFKNKRLLGTREVLNEEDEVQPNGKIFKKVILGQYNWLSYEDVFVRAFNFGNGLQMLGQKPKTNIAIFCETRAEWMIAAQACFMYNFQLVTLYATLGGPAIVHALNETEVTNIITSKELLQTKLKDIVSLVPRLRHIITVDGKPPTWSEFPKGIIVHTMAAVEALGAKASMENQPHSKPLPSDIAVIMYTSGSTGLPKGVMISHSNIIAGITGMAERIPELGEEDVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTLADQSSKIKKGSKGDTSMLKPTLMAAVPEIMDRIYKNVMNKVSEMSSFQRNLFILAYNYKMEQISKGRNTPLCDSFVFRKVRSLLGGNIRLLLCGGAPLSATTQRFMNICFCCPVGQGYGLTESAGAGTISEVWDYNTGRVGAPLVCCEIKLKNWEEGGYFNTDKPHPRGEILIGGQSVTMGYYKNEAKTKADFFEDENGQRWLCTGDIGEFEPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLVDNICAYANSYHSYVIGFVVPNQKELTELARKKGLKGTWEELCNSCEMENEVLKVLSEAAISASLEKFEIPVKIRLSPEPWTPETGLVTDAFKLKRKELKTHYQADIERMYGRK
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | IR21A,YR24A,FE25A,IE35A,LR32A,CP652A,LR29A,IR39A,YE38A,FE28A,FP44A,YR42A,FR43A,LE36A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 7.03525 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:01)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:01)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:01)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:01)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:01)
[INFO] FoldX: Building mutant model (00:08:06)
[INFO] FoldX: Starting FoldX energy minimalization (00:16:34)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:24:15)
[INFO] Main: Simulation completed successfully. (00:24:24)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | -0.0231 | |
| 2 | N | A | -1.4447 | |
| 3 | N | A | -1.5961 | |
| 4 | H | A | -1.1002 | |
| 5 | V | A | 0.2768 | |
| 6 | S | A | -0.5046 | |
| 7 | S | A | -0.8537 | |
| 8 | K | A | -1.7367 | |
| 9 | P | A | -1.2154 | |
| 10 | S | A | -0.6846 | |
| 11 | T | A | -0.6979 | |
| 12 | M | A | -0.0056 | |
| 13 | K | A | -1.6188 | |
| 14 | L | A | -1.1831 | |
| 15 | K | A | -1.9726 | |
| 16 | H | A | -1.3021 | |
| 17 | T | A | -0.6143 | |
| 18 | I | A | -0.5106 | |
| 19 | N | A | -1.5349 | |
| 20 | P | A | -1.6890 | |
| 21 | R | A | -2.5728 | mutated: IR21A |
| 22 | L | A | -1.2244 | |
| 23 | L | A | -2.0189 | |
| 24 | R | A | -3.6545 | mutated: YR24A |
| 25 | E | A | -3.2408 | mutated: FE25A |
| 26 | I | A | -2.3425 | |
| 27 | H | A | -3.2984 | |
| 28 | E | A | -4.0329 | mutated: FE28A |
| 29 | R | A | -3.9687 | mutated: LR29A |
| 30 | I | A | -2.5860 | |
| 31 | S | A | -2.9525 | |
| 32 | R | A | -3.9751 | mutated: LR32A |
| 33 | Y | A | -2.5931 | |
| 34 | T | A | -2.7602 | |
| 35 | E | A | -3.9813 | mutated: IE35A |
| 36 | E | A | -3.6394 | mutated: LE36A |
| 37 | T | A | -2.6043 | |
| 38 | E | A | -3.3693 | mutated: YE38A |
| 39 | R | A | -3.7879 | mutated: IR39A |
| 40 | P | A | -2.5380 | |
| 41 | F | A | -2.6113 | |
| 42 | R | A | -3.2764 | mutated: YR42A |
| 43 | R | A | -3.2650 | mutated: FR43A |
| 44 | P | A | -2.1215 | mutated: FP44A |
| 45 | S | A | -2.1251 | |
| 46 | E | A | -3.0365 | |
| 47 | S | A | -2.7355 | |
| 48 | R | A | -2.9285 | |
| 49 | Q | A | -3.0398 | |
| 50 | E | A | -3.6530 | |
| 51 | K | A | -2.5792 | |
| 52 | S | A | 0.0000 | |
| 53 | N | A | -2.5492 | |
| 54 | R | A | -1.7450 | |
| 55 | I | A | -0.0795 | |
| 56 | K | A | 0.0000 | |
| 57 | A | A | 0.0000 | |
| 58 | K | A | -0.6287 | |
| 59 | P | A | -0.8953 | |
| 60 | V | A | -0.4261 | |
| 61 | N | A | -1.6471 | |
| 62 | S | A | -1.7221 | |
| 63 | K | A | -2.3827 | |
| 64 | P | A | -1.7457 | |
| 65 | D | A | -1.8106 | |
| 66 | S | A | 0.0000 | |
| 67 | A | A | 0.0000 | |
| 68 | Y | A | -0.2928 | |
| 69 | R | A | -0.4585 | |
| 70 | S | A | 0.0000 | |
| 71 | V | A | -0.2023 | |
| 72 | N | A | -1.2792 | |
| 73 | S | A | 0.0000 | |
| 74 | L | A | -0.6494 | |
| 75 | D | A | -1.6131 | |
| 76 | G | A | -1.0535 | |
| 77 | L | A | -0.3948 | |
| 78 | A | A | -0.2614 | |
| 79 | S | A | 0.0779 | |
| 80 | V | A | 0.5403 | |
| 81 | L | A | 0.3262 | |
| 82 | Y | A | 0.1391 | |
| 83 | P | A | -0.2935 | |
| 84 | G | A | -0.6825 | |
| 85 | C | A | 0.0000 | |
| 86 | D | A | -0.6282 | |
| 87 | T | A | 0.0000 | |
| 88 | L | A | 0.0000 | |
| 89 | D | A | 0.0000 | |
| 90 | K | A | -1.0180 | |
| 91 | V | A | 0.0000 | |
| 92 | F | A | 0.0000 | |
| 93 | T | A | -0.9151 | |
| 94 | Y | A | -0.9381 | |
| 95 | A | A | 0.0000 | |
| 96 | K | A | -2.2796 | |
| 97 | N | A | -2.6408 | |
| 98 | K | A | -2.8803 | |
| 99 | F | A | 0.0000 | |
| 100 | K | A | -3.3560 | |
| 101 | N | A | -3.1499 | |
| 102 | K | A | -2.9378 | |
| 103 | R | A | -2.5076 | |
| 104 | L | A | 0.0000 | |
| 105 | L | A | 0.0000 | |
| 106 | G | A | 0.0000 | |
| 107 | T | A | -0.8228 | |
| 108 | R | A | -0.8529 | |
| 109 | E | A | -0.9915 | |
| 110 | V | A | 0.8534 | |
| 111 | L | A | 1.0692 | |
| 112 | N | A | -0.7776 | |
| 113 | E | A | -2.6893 | |
| 114 | E | A | -2.6510 | |
| 115 | D | A | -2.3203 | |
| 116 | E | A | -0.8775 | |
| 117 | V | A | 0.6999 | |
| 118 | Q | A | -0.3489 | |
| 119 | P | A | -0.8905 | |
| 120 | N | A | -1.7007 | |
| 121 | G | A | -1.0961 | |
| 122 | K | A | -1.3606 | |
| 123 | I | A | 0.4063 | |
| 124 | F | A | -0.1041 | |
| 125 | K | A | -2.0760 | |
| 126 | K | A | -2.4340 | |
| 127 | V | A | 0.0000 | |
| 128 | I | A | -0.4964 | |
| 129 | L | A | -0.0879 | |
| 130 | G | A | 0.0000 | |
| 131 | Q | A | -1.4156 | |
| 132 | Y | A | -1.3090 | |
| 133 | N | A | -1.8067 | |
| 134 | W | A | -0.8982 | |
| 135 | L | A | -0.8847 | |
| 136 | S | A | -1.7331 | |
| 137 | Y | A | 0.0000 | |
| 138 | E | A | -1.9143 | |
| 139 | D | A | -1.3762 | |
| 140 | V | A | 0.0000 | |
| 141 | F | A | -0.1338 | |
| 142 | V | A | 0.5114 | |
| 143 | R | A | -0.1653 | |
| 144 | A | A | 0.0000 | |
| 145 | F | A | 0.3202 | |
| 146 | N | A | -0.0977 | |
| 147 | F | A | 0.0000 | |
| 148 | G | A | 0.0000 | |
| 149 | N | A | 0.0000 | |
| 150 | G | A | 0.0000 | |
| 151 | L | A | 0.0000 | |
| 152 | Q | A | -1.0242 | |
| 153 | M | A | 0.0523 | |
| 154 | L | A | -0.1853 | |
| 155 | G | A | -0.8066 | |
| 156 | Q | A | 0.0000 | |
| 157 | K | A | -2.4526 | |
| 158 | P | A | 0.0000 | |
| 159 | K | A | -2.1544 | |
| 160 | T | A | -1.6667 | |
| 161 | N | A | -1.1686 | |
| 162 | I | A | 0.0000 | |
| 163 | A | A | 0.0000 | |
| 164 | I | A | 0.0000 | |
| 165 | F | A | 0.0000 | |
| 166 | C | A | 0.0000 | |
| 167 | E | A | -1.1985 | |
| 168 | T | A | -0.6562 | |
| 169 | R | A | -0.6472 | |
| 170 | A | A | 0.0000 | |
| 171 | E | A | -0.5345 | |
| 172 | W | A | 0.0000 | |
| 173 | M | A | 0.0000 | |
| 174 | I | A | 0.0000 | |
| 175 | A | A | 0.0000 | |
| 176 | A | A | 0.0000 | |
| 177 | Q | A | 0.0000 | |
| 178 | A | A | 0.0000 | |
| 179 | C | A | 0.0000 | |
| 180 | F | A | 0.0000 | |
| 181 | M | A | 0.0000 | |
| 182 | Y | A | 0.0000 | |
| 183 | N | A | 0.0000 | |
| 184 | F | A | 0.0000 | |
| 185 | Q | A | -0.7840 | |
| 186 | L | A | 0.0000 | |
| 187 | V | A | 0.0000 | |
| 188 | T | A | 0.0000 | |
| 189 | L | A | 0.0000 | |
| 190 | Y | A | 0.0000 | |
| 191 | A | A | -0.6119 | |
| 192 | T | A | -0.7041 | |
| 193 | L | A | -0.5871 | |
| 194 | G | A | -0.9632 | |
| 195 | G | A | -0.7395 | |
| 196 | P | A | 0.0219 | |
| 197 | A | A | 0.0209 | |
| 198 | I | A | 0.0000 | |
| 199 | V | A | 0.1394 | |
| 200 | H | A | -0.1213 | |
| 201 | A | A | 0.0000 | |
| 202 | L | A | 0.0000 | |
| 203 | N | A | -1.1010 | |
| 204 | E | A | -1.3707 | |
| 205 | T | A | 0.0000 | |
| 206 | E | A | -2.3124 | |
| 207 | V | A | 0.0000 | |
| 208 | T | A | -1.1838 | |
| 209 | N | A | 0.0000 | |
| 210 | I | A | 0.0000 | |
| 211 | I | A | 0.0000 | |
| 212 | T | A | 0.0000 | |
| 213 | S | A | 0.0000 | |
| 214 | K | A | -1.9716 | |
| 215 | E | A | -2.4971 | |
| 216 | L | A | 0.0000 | |
| 217 | L | A | 0.0000 | |
| 218 | Q | A | -1.8587 | |
| 219 | T | A | -1.6824 | |
| 220 | K | A | -1.9489 | |
| 221 | L | A | 0.0000 | |
| 222 | K | A | -2.3599 | |
| 223 | D | A | -2.3635 | |
| 224 | I | A | 0.0000 | |
| 225 | V | A | 0.0000 | |
| 226 | S | A | -0.2735 | |
| 227 | L | A | 0.8523 | |
| 228 | V | A | 0.0000 | |
| 229 | P | A | -0.7390 | |
| 230 | R | A | -1.5443 | |
| 231 | L | A | 0.0000 | |
| 232 | R | A | -1.1896 | |
| 233 | H | A | -0.2195 | |
| 234 | I | A | 0.0000 | |
| 235 | I | A | 0.0000 | |
| 236 | T | A | 0.0000 | |
| 237 | V | A | 0.0000 | |
| 238 | D | A | -1.4376 | |
| 239 | G | A | -1.8448 | |
| 240 | K | A | -2.1368 | |
| 241 | P | A | -1.1289 | |
| 242 | P | A | -0.9121 | |
| 243 | T | A | -0.5225 | |
| 244 | W | A | -0.5155 | |
| 245 | S | A | -0.9300 | |
| 246 | E | A | -2.0783 | |
| 247 | F | A | -1.0117 | |
| 248 | P | A | -1.2935 | |
| 249 | K | A | -2.0634 | |
| 250 | G | A | -1.2459 | |
| 251 | I | A | -0.5433 | |
| 252 | I | A | 0.8672 | |
| 253 | V | A | 0.5483 | |
| 254 | H | A | 0.0572 | |
| 255 | T | A | -0.6428 | |
| 256 | M | A | 0.0000 | |
| 257 | A | A | -0.3117 | |
| 258 | A | A | 0.1177 | |
| 259 | V | A | 0.0000 | |
| 260 | E | A | -0.1987 | |
| 261 | A | A | -0.2791 | |
| 262 | L | A | 0.0011 | |
| 263 | G | A | 0.0000 | |
| 264 | A | A | -0.4805 | |
| 265 | K | A | -1.4755 | |
| 266 | A | A | -1.1357 | |
| 267 | S | A | -1.1278 | |
| 268 | M | A | -0.7509 | |
| 269 | E | A | -2.2863 | |
| 270 | N | A | -2.2225 | |
| 271 | Q | A | -2.4048 | |
| 272 | P | A | -2.0447 | |
| 273 | H | A | -2.3163 | |
| 274 | S | A | -1.6097 | |
| 275 | K | A | -1.4515 | |
| 276 | P | A | 0.0000 | |
| 277 | L | A | 1.0359 | |
| 278 | P | A | 0.3772 | |
| 279 | S | A | 0.2695 | |
| 280 | D | A | 0.0000 | |
| 281 | I | A | 0.0979 | |
| 282 | A | A | 0.0000 | |
| 283 | V | A | 0.0000 | |
| 284 | I | A | 0.0000 | |
| 285 | M | A | 0.0000 | |
| 286 | Y | A | 0.0000 | |
| 287 | T | A | 0.0103 | |
| 288 | S | A | -0.0881 | |
| 289 | G | A | 0.0000 | |
| 290 | S | A | -0.9941 | |
| 291 | T | A | -0.5045 | |
| 292 | G | A | -0.2884 | |
| 293 | L | A | 1.1237 | |
| 294 | P | A | 0.0000 | |
| 295 | K | A | -0.3727 | |
| 296 | G | A | 0.0000 | |
| 297 | V | A | 0.0000 | |
| 298 | M | A | 0.1396 | |
| 299 | I | A | 0.0000 | |
| 300 | S | A | 0.0000 | |
| 301 | H | A | 0.0000 | |
| 302 | S | A | -0.1187 | |
| 303 | N | A | 0.0000 | |
| 304 | I | A | 0.0000 | |
| 305 | I | A | 0.0000 | |
| 306 | A | A | 0.0000 | |
| 307 | G | A | 0.0000 | |
| 308 | I | A | 0.0000 | |
| 309 | T | A | 0.0774 | |
| 310 | G | A | 0.0000 | |
| 311 | M | A | 0.0000 | |
| 312 | A | A | 0.0000 | |
| 313 | E | A | -1.1938 | |
| 314 | R | A | 0.0000 | |
| 315 | I | A | -0.3646 | |
| 316 | P | A | -0.8655 | |
| 317 | E | A | -2.1237 | |
| 318 | L | A | -1.2588 | |
| 319 | G | A | -1.4187 | |
| 320 | E | A | -2.2211 | |
| 321 | E | A | -2.4403 | |
| 322 | D | A | 0.0000 | |
| 323 | V | A | 0.0000 | |
| 324 | Y | A | 0.0000 | |
| 325 | I | A | 0.0000 | |
| 326 | G | A | 0.0000 | |
| 327 | Y | A | 0.0000 | |
| 328 | L | A | 0.0000 | |
| 329 | P | A | -0.4572 | |
| 330 | L | A | 0.0000 | |
| 331 | A | A | 0.0000 | |
| 332 | H | A | -0.1985 | |
| 333 | V | A | 0.0000 | |
| 334 | L | A | 0.1103 | |
| 335 | E | A | 0.0000 | |
| 336 | L | A | 0.0000 | |
| 337 | S | A | 0.0000 | |
| 338 | A | A | 0.0713 | |
| 339 | E | A | 0.0000 | |
| 340 | L | A | 0.0000 | |
| 341 | V | A | 0.0000 | |
| 342 | C | A | 0.0000 | |
| 343 | L | A | 0.0000 | |
| 344 | S | A | 0.0000 | |
| 345 | H | A | -0.8452 | |
| 346 | G | A | 0.0000 | |
| 347 | C | A | 0.0000 | |
| 348 | R | A | -1.1722 | |
| 349 | I | A | 0.0000 | |
| 350 | G | A | 0.0000 | |
| 351 | Y | A | 0.0000 | |
| 352 | S | A | -0.2552 | |
| 353 | S | A | -0.5431 | |
| 354 | P | A | -0.5387 | |
| 355 | Q | A | -1.1272 | |
| 356 | T | A | 0.0000 | |
| 357 | L | A | 0.0000 | |
| 358 | A | A | 0.0000 | |
| 359 | D | A | -2.1557 | |
| 360 | Q | A | -2.0260 | |
| 361 | S | A | 0.0000 | |
| 362 | S | A | -1.3112 | |
| 363 | K | A | -1.8724 | |
| 364 | I | A | 0.0000 | |
| 365 | K | A | -2.7745 | |
| 366 | K | A | -2.7088 | |
| 367 | G | A | -1.9085 | |
| 368 | S | A | -1.7386 | |
| 369 | K | A | -2.0386 | |
| 370 | G | A | 0.0000 | |
| 371 | D | A | 0.0000 | |
| 372 | T | A | 0.0000 | |
| 373 | S | A | -0.8856 | |
| 374 | M | A | -0.6578 | |
| 375 | L | A | 0.0000 | |
| 376 | K | A | -1.3417 | |
| 377 | P | A | 0.0000 | |
| 378 | T | A | -1.0730 | |
| 379 | L | A | 0.0000 | |
| 380 | M | A | 0.0000 | |
| 381 | A | A | 0.0000 | |
| 382 | A | A | 0.0000 | |
| 383 | V | A | -0.0350 | |
| 384 | P | A | 0.0000 | |
| 385 | E | A | -1.3517 | |
| 386 | I | A | 0.0000 | |
| 387 | M | A | 0.0000 | |
| 388 | D | A | -1.1545 | |
| 389 | R | A | -1.2127 | |
| 390 | I | A | 0.0000 | |
| 391 | Y | A | -0.8207 | |
| 392 | K | A | -1.5447 | |
| 393 | N | A | -1.6395 | |
| 394 | V | A | 0.0000 | |
| 395 | M | A | -1.5039 | |
| 396 | N | A | -2.5432 | |
| 397 | K | A | -2.6482 | |
| 398 | V | A | 0.0000 | |
| 399 | S | A | -2.1478 | |
| 400 | E | A | -2.7980 | |
| 401 | M | A | -1.4757 | |
| 402 | S | A | -0.3971 | |
| 403 | S | A | 0.0130 | |
| 404 | F | A | 1.4154 | |
| 405 | Q | A | -0.2240 | |
| 406 | R | A | -0.8302 | |
| 407 | N | A | 0.0294 | |
| 408 | L | A | 0.8047 | |
| 409 | F | A | 0.0000 | |
| 410 | I | A | 0.0000 | |
| 411 | L | A | 0.0000 | |
| 412 | A | A | 0.0000 | |
| 413 | Y | A | 0.0000 | |
| 414 | N | A | -0.9815 | |
| 415 | Y | A | -0.7821 | |
| 416 | K | A | 0.0000 | |
| 417 | M | A | 0.0000 | |
| 418 | E | A | -2.4312 | |
| 419 | Q | A | -2.0424 | |
| 420 | I | A | 0.0000 | |
| 421 | S | A | -2.0341 | |
| 422 | K | A | -2.6696 | |
| 423 | G | A | -2.5991 | |
| 424 | R | A | -2.5943 | |
| 425 | N | A | -1.8698 | |
| 426 | T | A | 0.0000 | |
| 427 | P | A | 0.0883 | |
| 428 | L | A | 0.8296 | |
| 429 | C | A | 0.0000 | |
| 430 | D | A | 0.0000 | |
| 431 | S | A | 0.2154 | |
| 432 | F | A | 1.3392 | |
| 433 | V | A | 0.0000 | |
| 434 | F | A | 0.0000 | |
| 435 | R | A | -2.2822 | |
| 436 | K | A | -2.4788 | |
| 437 | V | A | 0.0000 | |
| 438 | R | A | -1.9116 | |
| 439 | S | A | -1.7460 | |
| 440 | L | A | -1.0126 | |
| 441 | L | A | 0.0000 | |
| 442 | G | A | -1.1938 | |
| 443 | G | A | -1.8134 | |
| 444 | N | A | -1.6763 | |
| 445 | I | A | 0.0000 | |
| 446 | R | A | -0.6503 | |
| 447 | L | A | -0.0631 | |
| 448 | L | A | 0.0000 | |
| 449 | L | A | 0.4030 | |
| 450 | C | A | 0.0000 | |
| 451 | G | A | 0.0000 | |
| 452 | G | A | -0.1131 | |
| 453 | A | A | -0.3192 | |
| 454 | P | A | -0.3954 | |
| 455 | L | A | 0.0000 | |
| 456 | S | A | -0.4054 | |
| 457 | A | A | -0.2906 | |
| 458 | T | A | -0.0315 | |
| 459 | T | A | 0.0000 | |
| 460 | Q | A | 0.0000 | |
| 461 | R | A | -0.1782 | |
| 462 | F | A | 0.0000 | |
| 463 | M | A | 0.0000 | |
| 464 | N | A | 0.0000 | |
| 465 | I | A | 0.0000 | |
| 466 | C | A | 0.0000 | |
| 467 | F | A | 0.0000 | |
| 468 | C | A | -0.5545 | |
| 469 | C | A | 0.0000 | |
| 470 | P | A | 0.1376 | |
| 471 | V | A | 0.0000 | |
| 472 | G | A | 0.1280 | |
| 473 | Q | A | 0.0000 | |
| 474 | G | A | 0.0541 | |
| 475 | Y | A | 0.0759 | |
| 476 | G | A | -0.0106 | |
| 477 | L | A | 0.1272 | |
| 478 | T | A | 0.0392 | |
| 479 | E | A | 0.0000 | |
| 480 | S | A | 0.0000 | |
| 481 | A | A | 0.0000 | |
| 482 | G | A | -0.0417 | |
| 483 | A | A | 0.0000 | |
| 484 | G | A | 0.0000 | |
| 485 | T | A | 0.0000 | |
| 486 | I | A | 0.2682 | |
| 487 | S | A | 0.0000 | |
| 488 | E | A | 0.0000 | |
| 489 | V | A | 0.4496 | |
| 490 | W | A | -0.4831 | |
| 491 | D | A | 0.0000 | |
| 492 | Y | A | -0.4135 | |
| 493 | N | A | -0.6550 | |
| 494 | T | A | -0.4659 | |
| 495 | G | A | -0.3428 | |
| 496 | R | A | 0.0000 | |
| 497 | V | A | 0.0000 | |
| 498 | G | A | 0.0000 | |
| 499 | A | A | 0.0000 | |
| 500 | P | A | 0.0000 | |
| 501 | L | A | 0.0000 | |
| 502 | V | A | 0.0000 | |
| 503 | C | A | 0.0000 | |
| 504 | C | A | 0.0000 | |
| 505 | E | A | 0.0000 | |
| 506 | I | A | 0.0000 | |
| 507 | K | A | -1.0430 | |
| 508 | L | A | 0.0000 | |
| 509 | K | A | -1.9689 | |
| 510 | N | A | -2.4003 | |
| 511 | W | A | -2.1916 | |
| 512 | E | A | -3.0805 | |
| 513 | E | A | -3.0501 | |
| 514 | G | A | 0.0000 | |
| 515 | G | A | -1.6005 | |
| 516 | Y | A | -1.2152 | |
| 517 | F | A | -1.0880 | |
| 518 | N | A | 0.0000 | |
| 519 | T | A | -1.0039 | |
| 520 | D | A | -1.3157 | |
| 521 | K | A | -2.0349 | |
| 522 | P | A | -1.5850 | |
| 523 | H | A | -1.3081 | |
| 524 | P | A | -1.1412 | |
| 525 | R | A | -1.0639 | |
| 526 | G | A | 0.0000 | |
| 527 | E | A | 0.0000 | |
| 528 | I | A | 0.0000 | |
| 529 | L | A | 0.0000 | |
| 530 | I | A | 0.0000 | |
| 531 | G | A | 0.0000 | |
| 532 | G | A | 0.0000 | |
| 533 | Q | A | -0.6907 | |
| 534 | S | A | 0.0000 | |
| 535 | V | A | 0.0000 | |
| 536 | T | A | 0.0000 | |
| 537 | M | A | 0.3241 | |
| 538 | G | A | 0.0000 | |
| 539 | Y | A | 0.0000 | |
| 540 | Y | A | -1.2120 | |
| 541 | K | A | -2.4822 | |
| 542 | N | A | -2.5922 | |
| 543 | E | A | -3.1200 | |
| 544 | A | A | -2.0398 | |
| 545 | K | A | -2.0521 | |
| 546 | T | A | -1.9803 | |
| 547 | K | A | -2.4864 | |
| 548 | A | A | -1.1819 | |
| 549 | D | A | -0.8324 | |
| 550 | F | A | 0.0000 | |
| 551 | F | A | -1.0043 | |
| 552 | E | A | -3.0626 | |
| 553 | D | A | -3.0047 | |
| 554 | E | A | -3.3970 | |
| 555 | N | A | -3.0545 | |
| 556 | G | A | -2.6287 | |
| 557 | Q | A | -2.2919 | |
| 558 | R | A | -1.9365 | |
| 559 | W | A | 0.0000 | |
| 560 | L | A | 0.0000 | |
| 561 | C | A | -0.0091 | |
| 562 | T | A | 0.0000 | |
| 563 | G | A | 0.0000 | |
| 564 | D | A | 0.0000 | |
| 565 | I | A | 0.0000 | |
| 566 | G | A | 0.0000 | |
| 567 | E | A | -0.5287 | |
| 568 | F | A | 0.0000 | |
| 569 | E | A | -0.8718 | |
| 570 | P | A | -0.6216 | |
| 571 | D | A | -0.6703 | |
| 572 | G | A | 0.0000 | |
| 573 | C | A | 0.0000 | |
| 574 | L | A | 0.0000 | |
| 575 | K | A | -0.4666 | |
| 576 | I | A | 0.2449 | |
| 577 | I | A | -0.0068 | |
| 578 | D | A | 0.0000 | |
| 579 | R | A | -1.5679 | |
| 580 | K | A | -1.9060 | |
| 581 | K | A | -2.3086 | |
| 582 | D | A | -1.6975 | |
| 583 | L | A | 0.0000 | |
| 584 | V | A | -1.0876 | |
| 585 | K | A | -1.6013 | |
| 586 | L | A | 0.0000 | |
| 587 | Q | A | -1.3486 | |
| 588 | A | A | -0.8445 | |
| 589 | G | A | -1.2050 | |
| 590 | E | A | -1.2126 | |
| 591 | Y | A | -0.8723 | |
| 592 | V | A | 0.0000 | |
| 593 | S | A | 0.0000 | |
| 594 | L | A | 0.0000 | |
| 595 | G | A | -0.8886 | |
| 596 | K | A | -1.3492 | |
| 597 | V | A | 0.0000 | |
| 598 | E | A | 0.0000 | |
| 599 | A | A | -0.7015 | |
| 600 | A | A | -0.3250 | |
| 601 | L | A | 0.0000 | |
| 602 | K | A | -0.9713 | |
| 603 | N | A | -1.0208 | |
| 604 | L | A | -0.6314 | |
| 605 | P | A | -1.1546 | |
| 606 | L | A | 0.0000 | |
| 607 | V | A | 0.0000 | |
| 608 | D | A | -2.3481 | |
| 609 | N | A | -1.0972 | |
| 610 | I | A | 0.0000 | |
| 611 | C | A | 0.0000 | |
| 612 | A | A | 0.0000 | |
| 613 | Y | A | 0.0000 | |
| 614 | A | A | 0.0000 | |
| 615 | N | A | -0.4036 | |
| 616 | S | A | -0.5480 | |
| 617 | Y | A | 0.4951 | |
| 618 | H | A | -0.2526 | |
| 619 | S | A | -0.5977 | |
| 620 | Y | A | 0.0250 | |
| 621 | V | A | 0.0000 | |
| 622 | I | A | 0.0000 | |
| 623 | G | A | 0.0000 | |
| 624 | F | A | 0.0000 | |
| 625 | V | A | 0.0000 | |
| 626 | V | A | 0.0000 | |
| 627 | P | A | 0.0000 | |
| 628 | N | A | -2.3013 | |
| 629 | Q | A | -2.6615 | |
| 630 | K | A | -2.8365 | |
| 631 | E | A | -2.3140 | |
| 632 | L | A | 0.0000 | |
| 633 | T | A | -2.3652 | |
| 634 | E | A | -2.4604 | |
| 635 | L | A | -2.1169 | |
| 636 | A | A | 0.0000 | |
| 637 | R | A | -3.6535 | |
| 638 | K | A | -3.3168 | |
| 639 | K | A | -3.2676 | |
| 640 | G | A | -2.4142 | |
| 641 | L | A | -2.1976 | |
| 642 | K | A | -2.5662 | |
| 643 | G | A | -2.2732 | |
| 644 | T | A | -1.8298 | |
| 645 | W | A | -1.9865 | |
| 646 | E | A | -3.0616 | |
| 647 | E | A | -3.4188 | |
| 648 | L | A | 0.0000 | |
| 649 | C | A | 0.0000 | |
| 650 | N | A | -2.5313 | |
| 651 | S | A | -2.2134 | |
| 652 | P | A | -1.9787 | mutated: CP652A |
| 653 | E | A | -2.6461 | |
| 654 | M | A | 0.0000 | |
| 655 | E | A | 0.0000 | |
| 656 | N | A | -2.3578 | |
| 657 | E | A | -1.8631 | |
| 658 | V | A | 0.0000 | |
| 659 | L | A | -1.3196 | |
| 660 | K | A | -2.0344 | |
| 661 | V | A | -0.9398 | |
| 662 | L | A | 0.0000 | |
| 663 | S | A | -0.7248 | |
| 664 | E | A | -1.4320 | |
| 665 | A | A | -0.4281 | |
| 666 | A | A | 0.0000 | |
| 667 | I | A | 0.6184 | |
| 668 | S | A | 0.2219 | |
| 669 | A | A | 0.0183 | |
| 670 | S | A | -0.2082 | |
| 671 | L | A | 0.0000 | |
| 672 | E | A | -2.1807 | |
| 673 | K | A | -1.8784 | |
| 674 | F | A | -0.8318 | |
| 675 | E | A | 0.0000 | |
| 676 | I | A | 0.0000 | |
| 677 | P | A | 0.0000 | |
| 678 | V | A | 0.6375 | |
| 679 | K | A | -0.4020 | |
| 680 | I | A | 0.0000 | |
| 681 | R | A | -0.8683 | |
| 682 | L | A | 0.0000 | |
| 683 | S | A | 0.0000 | |
| 684 | P | A | -1.5859 | |
| 685 | E | A | -1.0683 | |
| 686 | P | A | -1.0776 | |
| 687 | W | A | 0.0000 | |
| 688 | T | A | -0.7662 | |
| 689 | P | A | -1.0182 | |
| 690 | E | A | -2.0274 | |
| 691 | T | A | -1.2883 | |
| 692 | G | A | -1.2097 | |
| 693 | L | A | 0.0000 | |
| 694 | V | A | 0.0000 | |
| 695 | T | A | -0.3898 | |
| 696 | D | A | -0.4768 | |
| 697 | A | A | -0.0825 | |
| 698 | F | A | 0.3074 | |
| 699 | K | A | -0.4426 | |
| 700 | L | A | -0.6079 | |
| 701 | K | A | -1.4484 | |
| 702 | R | A | -2.1623 | |
| 703 | K | A | -2.8915 | |
| 704 | E | A | -2.6705 | |
| 705 | L | A | 0.0000 | |
| 706 | K | A | -2.2452 | |
| 707 | T | A | -1.8933 | |
| 708 | H | A | -1.8087 | |
| 709 | Y | A | 0.0000 | |
| 710 | Q | A | -1.5935 | |
| 711 | A | A | -1.2810 | |
| 712 | D | A | -1.2824 | |
| 713 | I | A | 0.0000 | |
| 714 | E | A | -2.1883 | |
| 715 | R | A | -2.2592 | |
| 716 | M | A | 0.0000 | |
| 717 | Y | A | -1.2783 | |
| 718 | G | A | -2.2396 | |
| 719 | R | A | -3.2651 | |
| 720 | K | A | -2.7464 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine