Project name: fvghhkghjklgb

Chain sequence(s)	E: KIDEDIRNLILERRSEVYKFPEDFYKLPGIDFTDEEWKAFVNGGIDIEKMGAARVNAMLDQLFDDFELAMIGKAKENYYNDNKLKKEMKFYEYFDEFKREQLKKWLDNYRDDVIGGTGRAYTASGNYIANAYVEVALESSSLGSGSYLLRMRFTDYSKGQEPMPSGRQNRRDWIENNLDKLK; F: KIDEDIRNLILERRSEVYKFPEDFYKLPGIDFTDEEWKAFVNGGIDIEKMGAARVNAMLDQLFDDFELAMIGKAKENYYNDNKLKKEMKFYEYFDEFKREQLKKWLDNYRDDVIGGTGRAYTASGNYIANAYVEVALESSSLGSGSYLLRMRFTDYSKGQEPMPSGRQNRRDWIENNLDKLK
Selected Chain(s)	E,F
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:08:21)
[INFO]       Main:     Simulation completed successfully.                                          (00:08:24)

• Minimal score value: -4.4567
• Maximal score value: 0.8812
• Average score: -1.1947
• Total score value: -434.8638

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	K	E	-2.8108
2	I	E	0.0000
3	D	E	-2.6812
4	E	E	-3.0022
5	D	E	-2.0034
6	I	E	0.0000
7	R	E	-1.5488
8	N	E	-1.4014
9	L	E	0.0000
10	I	E	0.0000
11	L	E	-0.5694
12	E	E	-1.2674
13	R	E	0.0000
14	R	E	-0.9872
15	S	E	-1.1499
16	E	E	-1.7557
17	V	E	-0.8764
18	Y	E	0.0000
19	K	E	-1.1060
20	F	E	0.6900
21	P	E	-0.3477
22	E	E	-1.3252
23	D	E	-0.7045
24	F	E	0.0000
25	Y	E	0.0000
26	K	E	-2.4269
27	L	E	0.0000
28	P	E	-1.3355
29	G	E	-1.5908
30	I	E	0.0000
31	D	E	-2.7909
32	F	E	0.0000
33	T	E	-2.4980
34	D	E	-3.2469
35	E	E	-3.3651
36	E	E	-2.8109
37	W	E	0.0000
38	K	E	-3.0593
39	A	E	-2.2566
40	F	E	0.0000
41	V	E	-0.8293
42	N	E	-1.7587
43	G	E	-1.7735
44	G	E	-1.3683
45	I	E	-1.3446
46	D	E	-2.4806
47	I	E	0.0000
48	E	E	-3.0298
49	K	E	-2.9109
50	M	E	0.0000
51	G	E	-2.1099
52	A	E	0.0000
53	A	E	-1.6403
54	R	E	-1.7947
55	V	E	0.0000
56	N	E	-1.4405
57	A	E	-1.5840
58	M	E	0.0000
59	L	E	0.0000
60	D	E	-2.0631
61	Q	E	-0.9433
62	L	E	0.0000
63	F	E	0.0000
64	D	E	-0.6701
65	D	E	-0.4498
66	F	E	0.0000
67	E	E	0.0000
68	L	E	-0.0330
69	A	E	0.0000
70	M	E	0.0000
71	I	E	0.0000
72	G	E	-1.3531
73	K	E	-1.1307
74	A	E	0.0000
75	K	E	0.0000
76	E	E	-2.6364
77	N	E	-1.9416
78	Y	E	0.0000
79	Y	E	-1.9280
80	N	E	-2.7319
81	D	E	-3.1745
82	N	E	-3.7877
83	K	E	-3.9967
84	L	E	-3.5047
85	K	E	-4.1963
86	K	E	-4.3757
87	E	E	-3.8993
88	M	E	-2.5773
89	K	E	-2.5901
90	F	E	0.0000
91	Y	E	-1.0287
92	E	E	-1.6197
93	Y	E	-1.3586
94	F	E	0.0000
95	D	E	-1.4381
96	E	E	-1.9930
97	F	E	0.0000
98	K	E	0.0000
99	R	E	-2.3204
100	E	E	-2.8684
101	Q	E	0.0000
102	L	E	0.0000
103	K	E	-3.1488
104	K	E	-3.0035
105	W	E	0.0000
106	L	E	-2.8705
107	D	E	-3.4786
108	N	E	-3.0338
109	Y	E	-2.3360
110	R	E	-3.2584
111	D	E	-3.1939
112	D	E	-1.8960
113	V	E	0.0000
114	I	E	-1.3748
115	G	E	-1.1221
116	G	E	-0.6883
117	T	E	-0.9288
118	G	E	-1.1681
119	R	E	-1.0305
120	A	E	0.0000
121	Y	E	0.8812
122	T	E	0.0000
123	A	E	-0.9770
124	S	E	-0.8484
125	G	E	-0.7644
126	N	E	-0.7722
127	Y	E	0.3821
128	I	E	0.1358
129	A	E	-0.5013
130	N	E	-1.5638
131	A	E	-0.8443
132	Y	E	0.0000
133	V	E	0.0000
134	E	E	-0.8663
135	V	E	0.0000
136	A	E	0.0000
137	L	E	0.0000
138	E	E	-1.2677
139	S	E	-0.6747
140	S	E	0.0000
141	S	E	-0.2780
142	L	E	0.1404
143	G	E	-0.2408
144	S	E	-0.4487
145	G	E	-0.6505
146	S	E	-0.2975
147	Y	E	-0.1560
148	L	E	0.0000
149	L	E	-0.0574
150	R	E	-0.4354
151	M	E	0.0000
152	R	E	-0.6632
153	F	E	0.0000
154	T	E	0.0000
155	D	E	-1.3292
156	Y	E	-0.8633
157	S	E	0.0000
158	K	E	-2.2570
159	G	E	-1.8644
160	Q	E	-2.2479
161	E	E	-2.2709
162	P	E	-1.5756
163	M	E	-1.2207
164	P	E	-1.2446
165	S	E	-1.1407
166	G	E	-1.6766
167	R	E	-2.6320
168	Q	E	-3.0538
169	N	E	-2.8055
170	R	E	-2.4656
171	R	E	0.0000
172	D	E	-2.8984
173	W	E	0.0000
174	I	E	0.0000
175	E	E	-2.2324
176	N	E	-2.3480
177	N	E	0.0000
178	L	E	-1.8424
179	D	E	-2.4892
180	K	E	-2.1014
181	L	E	0.0000
182	K	E	-1.6939
1	K	F	-2.7421
2	I	F	0.0000
3	D	F	-2.5905
4	E	F	-2.9399
5	D	F	-2.0454
6	I	F	0.0000
7	R	F	-1.4653
8	N	F	-1.3043
9	L	F	0.0000
10	I	F	0.0000
11	L	F	-0.4338
12	E	F	-1.0659
13	R	F	0.0000
14	R	F	-0.7100
15	S	F	-0.7757
16	E	F	-0.8255
17	V	F	-0.5070
18	Y	F	0.0000
19	K	F	-1.1390
20	F	F	0.3216
21	P	F	-0.5715
22	E	F	-1.5794
23	D	F	-0.8403
24	F	F	0.0000
25	Y	F	0.0000
26	K	F	-2.5260
27	L	F	0.0000
28	P	F	-1.3629
29	G	F	-1.6406
30	I	F	0.0000
31	D	F	-2.8212
32	F	F	0.0000
33	T	F	-2.3988
34	D	F	-2.9977
35	E	F	-3.2202
36	E	F	-2.7445
37	W	F	0.0000
38	K	F	-3.0105
39	A	F	-2.2250
40	F	F	0.0000
41	V	F	-0.8891
42	N	F	-1.7910
43	G	F	-1.7362
44	G	F	-1.3471
45	I	F	-1.2895
46	D	F	-2.3363
47	I	F	0.0000
48	E	F	-2.9748
49	K	F	-2.8668
50	M	F	0.0000
51	G	F	-2.1302
52	A	F	0.0000
53	A	F	-1.6507
54	R	F	-1.8270
55	V	F	0.0000
56	N	F	-1.5017
57	A	F	-1.6895
58	M	F	0.0000
59	L	F	0.0000
60	D	F	-2.3074
61	Q	F	-1.0740
62	L	F	0.0000
63	F	F	0.0000
64	D	F	0.0000
65	D	F	-0.4139
66	F	F	0.0000
67	E	F	0.0000
68	L	F	0.1256
69	A	F	0.0000
70	M	F	0.0000
71	I	F	0.0000
72	G	F	-1.2050
73	K	F	0.0000
74	A	F	0.0000
75	K	F	0.0000
76	E	F	-2.7459
77	N	F	-2.0329
78	Y	F	0.0000
79	Y	F	-1.9963
80	N	F	-2.8195
81	D	F	-3.2534
82	N	F	-3.8259
83	K	F	-4.0379
84	L	F	-3.6592
85	K	F	-4.3303
86	K	F	-4.4567
87	E	F	-4.0233
88	M	F	-2.8268
89	K	F	-2.9264
90	F	F	0.0000
91	Y	F	-1.2638
92	E	F	-2.1194
93	Y	F	-1.6827
94	F	F	0.0000
95	D	F	0.0000
96	E	F	-2.3188
97	F	F	-1.5872
98	K	F	0.0000
99	R	F	-2.2824
100	E	F	-2.7811
101	Q	F	0.0000
102	L	F	0.0000
103	K	F	-2.7686
104	K	F	-2.6474
105	W	F	0.0000
106	L	F	0.0000
107	D	F	-3.3372
108	N	F	-2.9082
109	Y	F	-2.3095
110	R	F	-3.0933
111	D	F	-3.1517
112	D	F	-1.8713
113	V	F	0.0000
114	I	F	-1.3811
115	G	F	-1.0888
116	G	F	0.0000
117	T	F	-0.9072
118	G	F	-1.2309
119	R	F	-1.1856
120	A	F	0.0000
121	Y	F	0.8368
122	T	F	-0.0997
123	A	F	-1.0203
124	S	F	-0.8686
125	G	F	-0.7565
126	N	F	-0.7660
127	Y	F	0.3419
128	I	F	0.0535
129	A	F	-0.6049
130	N	F	-1.6670
131	A	F	0.0000
132	Y	F	0.0000
133	V	F	0.0000
134	E	F	-0.7714
135	V	F	0.0000
136	A	F	0.0000
137	L	F	0.0000
138	E	F	-1.3034
139	S	F	-0.7645
140	S	F	-0.4357
141	S	F	-0.3748
142	L	F	-0.0228
143	G	F	-0.3029
144	S	F	-0.4739
145	G	F	-0.6755
146	S	F	-0.3727
147	Y	F	-0.2237
148	L	F	0.0000
149	L	F	-0.0561
150	R	F	-0.3806
151	M	F	0.0000
152	R	F	-0.4688
153	F	F	0.0000
154	T	F	0.0000
155	D	F	0.0000
156	Y	F	-0.4775
157	S	F	0.0000
158	K	F	-2.1398
159	G	F	-1.8186
160	Q	F	-2.2605
161	E	F	-2.2904
162	P	F	-1.5599
163	M	F	-1.2069
164	P	F	-1.2216
165	S	F	-1.1011
166	G	F	-1.6488
167	R	F	-2.6125
168	Q	F	-3.0269
169	N	F	-2.7210
170	R	F	-2.4146
171	R	F	-2.7344
172	D	F	-2.7369
173	W	F	0.0000
174	I	F	0.0000
175	E	F	-1.9819
176	N	F	-2.2118
177	N	F	0.0000
178	L	F	-1.6463
179	D	F	-2.3403
180	K	F	-1.8550
181	L	F	0.0000
182	K	F	-1.3057