Project name: RFC10

Chain sequence(s)	A: TTVTVNSKVEVTGANVGAVAEVKNTITTGDATKKTATSTLKVDKKPSPDDYVKTATLTATTPATPATVTVTQEKKIKKVEFKNPNKNGTISGTVKQNTTTTTT
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:16)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:17)

• Minimal score value: -3.3289
• Maximal score value: 1.2786
• Average score: -0.8798
• Total score value: -90.6228

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	T	A	-0.1426
2	T	A	-0.1276
3	V	A	0.0000
4	T	A	-0.2457
5	V	A	0.0000
6	N	A	-1.1520
7	S	A	0.0000
8	K	A	-1.7344
9	V	A	0.0000
10	E	A	-1.0625
11	V	A	0.0000
12	T	A	-1.1492
13	G	A	-0.7575
14	A	A	-0.8140
15	N	A	-1.2774
16	V	A	0.0000
17	G	A	0.0000
18	A	A	0.0000
19	V	A	-1.6222
20	A	A	0.0000
21	E	A	-2.1974
22	V	A	0.0000
23	K	A	-1.9113
24	N	A	0.0000
25	T	A	-0.4081
26	I	A	0.0000
27	T	A	-0.7925
28	T	A	0.0000
29	G	A	-1.0855
30	D	A	-1.1688
31	A	A	-0.8176
32	T	A	-1.4673
33	K	A	-2.6386
34	K	A	-2.6085
35	T	A	-1.2774
36	A	A	-0.6235
37	T	A	-0.4367
38	S	A	-0.5887
39	T	A	-1.0270
40	L	A	0.0000
41	K	A	-2.6111
42	V	A	0.0000
43	D	A	-2.8525
44	K	A	-2.0969
45	K	A	-2.2831
46	P	A	-1.8957
47	S	A	-1.6380
48	P	A	-1.7353
49	D	A	-2.5692
50	D	A	-2.2913
51	Y	A	-0.4470
52	V	A	0.3403
53	K	A	-0.5799
54	T	A	-0.9977
55	A	A	-0.6879
56	T	A	-0.4917
57	L	A	0.0000
58	T	A	-0.2335
59	A	A	0.0000
60	T	A	-0.3385
61	T	A	0.0000
62	P	A	-0.3511
63	A	A	-0.2872
64	T	A	-0.3057
65	P	A	-0.3454
66	A	A	-0.2157
67	T	A	-0.2490
68	V	A	-0.0323
69	T	A	0.3104
70	V	A	0.2128
71	T	A	-0.4867
72	Q	A	-1.5616
73	E	A	-2.3365
74	K	A	-2.5261
75	K	A	-2.1009
76	I	A	-0.4298
77	K	A	-1.8646
78	K	A	-1.5572
79	V	A	-0.5288
80	E	A	-0.7044
81	F	A	0.5816
82	K	A	-1.1772
83	N	A	-1.7180
84	P	A	-1.8175
85	N	A	-2.9188
86	K	A	-3.3289
87	N	A	-2.6472
88	G	A	-1.5258
89	T	A	-0.0651
90	I	A	1.2786
91	S	A	0.5475
92	G	A	-0.1865
93	T	A	-0.5322
94	V	A	-0.1962
95	K	A	-1.5505
96	Q	A	-1.8407
97	N	A	-2.3009
98	T	A	-1.6939
99	T	A	-0.8287
100	T	A	-0.3232
101	T	A	-0.2485
102	T	A	-0.0786
103	T	A	-0.1493