Chain sequence(s) |
A: MIAGVDQALAATGQASQRAAGASGGVTVGVGVGTEQRNLSVVAPSQFTFSSRSPDFVDETAGQSWCAILGLNQFHFAVTNDGVI
input PDB |
Selected Chain(s) | A |
Distance of aggregation | 10 Å |
FoldX usage | Yes |
Dynamic mode | No |
Automated mutations | No |
Downloads | Download all the data |
Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00) [WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow to prevent this behavior) (00:00:00) [INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00) [INFO] runJob: Creating pdb object from: input.pdb (00:00:00) [INFO] FoldX: Starting FoldX energy minimalization (00:00:00) [INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:00:30) [INFO] Main: Simulation completed successfully. (00:00:31) |
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
residue index | residue name | chain | Aggrescan3D score | mutation |
---|---|---|---|---|
residue index | residue name | chain | Aggrescan3D score | |
1 | M | A | 2.0395 | |
2 | I | A | 2.6276 | |
3 | A | A | 0.9960 | |
4 | G | A | 0.3873 | |
5 | V | A | 1.4759 | |
6 | D | A | -0.5790 | |
7 | Q | A | -1.0650 | |
8 | A | A | 0.0886 | |
9 | L | A | 0.8456 | |
10 | A | A | -0.3358 | |
11 | A | A | -0.5617 | |
12 | T | A | -0.2420 | |
13 | G | A | -0.7448 | |
14 | Q | A | -1.5557 | |
15 | A | A | -1.0963 | |
16 | S | A | -1.3627 | |
17 | Q | A | -2.6703 | |
18 | R | A | -2.6158 | |
19 | A | A | 0.0000 | |
20 | A | A | -1.5149 | |
21 | G | A | -1.4633 | |
22 | A | A | -1.1481 | |
23 | S | A | -0.5997 | |
24 | G | A | -0.4363 | |
25 | G | A | 0.0551 | |
26 | V | A | 0.1005 | |
27 | T | A | 0.1123 | |
28 | V | A | 0.1421 | |
29 | G | A | -0.9531 | |
30 | V | A | 0.0000 | |
31 | G | A | -1.9421 | |
32 | V | A | -1.2921 | |
33 | G | A | -1.3836 | |
34 | T | A | -1.6188 | |
35 | E | A | -3.0461 | |
36 | Q | A | -3.2250 | |
37 | R | A | -3.2512 | |
38 | N | A | -2.2697 | |
39 | L | A | -0.2550 | |
40 | S | A | 0.2944 | |
41 | V | A | 1.3483 | |
42 | V | A | 1.6444 | |
43 | A | A | 0.7406 | |
44 | P | A | -0.3552 | |
45 | S | A | -0.2067 | |
46 | Q | A | 0.1314 | |
47 | F | A | 1.7508 | |
48 | T | A | 1.3419 | |
49 | F | A | 1.9938 | |
50 | S | A | 0.4988 | |
51 | S | A | -0.4134 | |
52 | R | A | -1.7910 | |
53 | S | A | -1.4828 | |
54 | P | A | -0.9639 | |
55 | D | A | -1.0394 | |
56 | F | A | 0.2715 | |
57 | V | A | 0.4921 | |
58 | D | A | -1.7545 | |
59 | E | A | -2.4486 | |
60 | T | A | -1.5027 | |
61 | A | A | -1.0608 | |
62 | G | A | -0.8438 | |
63 | Q | A | -1.3136 | |
64 | S | A | -0.3149 | |
65 | W | A | 0.2008 | |
66 | C | A | 0.1582 | |
67 | A | A | 0.2743 | |
68 | I | A | 0.1666 | |
69 | L | A | 0.6454 | |
70 | G | A | 0.1585 | |
71 | L | A | 1.1186 | |
72 | N | A | 0.1304 | |
73 | Q | A | -0.4178 | |
74 | F | A | 0.0318 | |
75 | H | A | -0.3895 | |
76 | F | A | 0.8188 | |
77 | A | A | 0.6464 | |
78 | V | A | 1.0963 | |
79 | T | A | -0.1168 | |
80 | N | A | -1.2711 | |
81 | D | A | -1.4537 | |
82 | G | A | -0.0872 | |
83 | V | A | 1.7998 | |
84 | I | A | 1.7940 |