Project name: 93516b0b848ff39

Chain sequence(s)	G: MTQSPSSLSASVGDRVTITCRASQSVSSAVAWYQQKPGKAPKLLIYSASSLYSGVPSRFSGSRSGTDFTLTISSLQPEDFATYYCQQSSYSLITFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
Selected Chain(s)	G
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with G chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:50)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:51)

• Minimal score value: -3.4498
• Maximal score value: 2.8803
• Average score: -0.6495
• Total score value: -135.7487

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
4	M	G	-0.5755
5	T	G	-0.8381
6	Q	G	0.0000
7	S	G	-0.7382
8	P	G	-0.4679
9	S	G	-0.8212
10	S	G	-0.7515
11	L	G	-0.4142
12	S	G	-0.8636
13	A	G	0.0000
14	S	G	-1.3539
15	V	G	-0.7004
16	G	G	-1.1987
17	D	G	-1.9331
18	R	G	-2.4116
19	V	G	0.0000
20	T	G	-0.6763
21	I	G	0.0000
22	T	G	-0.9637
23	C	G	0.0000
24	R	G	-2.4079
25	A	G	0.0000
26	S	G	-0.5600
27	Q	G	-0.1313
28	S	G	-0.2815
29	V	G	-0.6265
36	S	G	-0.2576
37	S	G	0.1156
38	A	G	-0.2995
39	V	G	0.0000
40	A	G	0.5660
41	W	G	0.0000
42	Y	G	0.0444
43	Q	G	0.0000
44	Q	G	-1.4193
45	K	G	-1.7161
46	P	G	-1.4780
47	G	G	-1.5891
48	K	G	-2.3869
49	A	G	-1.3962
50	P	G	-1.2907
51	K	G	-1.3195
52	L	G	0.1824
53	L	G	0.0000
54	I	G	0.0000
55	Y	G	0.9741
56	S	G	0.0047
57	A	G	-0.5164
65	S	G	-0.3003
66	S	G	0.4823
67	L	G	1.0343
68	Y	G	1.1676
69	S	G	0.2811
70	G	G	-0.1892
71	V	G	0.0761
72	P	G	-0.1712
74	S	G	-0.3738
75	R	G	-0.7948
76	F	G	0.0000
77	S	G	-0.3184
78	G	G	-0.5379
79	S	G	-1.4380
80	R	G	-2.5970
83	S	G	-1.8039
84	G	G	-1.4970
85	T	G	-1.5725
86	D	G	-2.2118
87	F	G	0.0000
88	T	G	-1.1240
89	L	G	0.0000
90	T	G	-0.6261
91	I	G	0.0000
92	S	G	-1.3883
93	S	G	-1.3742
94	L	G	0.0000
95	Q	G	-0.9745
96	P	G	-0.9324
97	E	G	-1.1315
98	D	G	0.0000
99	F	G	-1.1961
100	A	G	0.0000
101	T	G	-0.8702
102	Y	G	0.0000
103	Y	G	-0.0546
104	C	G	0.0000
105	Q	G	0.7020
106	Q	G	0.0000
107	S	G	1.1790
108	S	G	1.3010
109	Y	G	1.8137
114	S	G	1.3973
115	L	G	2.4122
116	I	G	2.8803
117	T	G	1.5232
118	F	G	1.1869
119	G	G	0.0000
120	Q	G	-1.0551
121	G	G	0.0000
122	T	G	0.0000
123	K	G	-1.4348
124	V	G	0.0000
125	E	G	-1.6212
126	I	G	0.0000
127	K	G	-2.3720
128	R	G	-1.5120
129	T	G	0.1357
130	V	G	1.4654
131	A	G	0.6975
132	A	G	0.3025
133	P	G	0.0637
134	S	G	-0.1022
135	V	G	0.0000
136	F	G	1.0574
137	I	G	1.0617
138	F	G	1.3701
139	P	G	0.0077
140	P	G	-0.7070
141	S	G	-1.8036
142	D	G	-3.1875
143	E	G	-3.3735
144	Q	G	-2.4805
145	L	G	-2.5719
146	K	G	-2.9702
147	S	G	-1.8575
148	G	G	-1.2027
149	T	G	-0.9731
150	A	G	0.0000
151	S	G	-0.0036
152	V	G	0.0000
153	V	G	0.6705
154	C	G	0.0000
155	L	G	0.5299
156	L	G	0.0000
157	N	G	-0.4659
158	N	G	-1.0272
159	F	G	0.0000
160	Y	G	-0.4279
161	P	G	-1.0349
162	R	G	-2.6186
163	E	G	-3.1660
164	A	G	-2.2506
165	K	G	-2.3743
166	V	G	-0.9612
167	S	G	-0.1392
168	W	G	0.0000
169	Y	G	0.1545
170	V	G	0.0000
171	D	G	-1.5288
172	N	G	-1.2203
173	A	G	-0.0282
174	L	G	1.0486
175	Q	G	-0.0684
176	S	G	-0.5869
177	G	G	-1.4528
178	N	G	-1.9306
179	S	G	-1.8462
180	Q	G	-2.4694
181	E	G	-2.1207
182	S	G	-0.7199
183	V	G	0.3266
184	T	G	-0.5073
185	E	G	-1.9774
186	Q	G	-2.8068
187	D	G	-3.0737
188	S	G	-2.4471
189	K	G	-2.6978
190	D	G	0.0000
191	S	G	0.0000
192	T	G	0.0000
193	Y	G	0.0000
194	S	G	-0.5800
195	L	G	0.0000
196	S	G	-0.2743
197	S	G	0.0000
198	T	G	-0.7649
199	L	G	0.0000
200	T	G	-0.8327
201	L	G	0.0000
202	S	G	-1.1104
203	K	G	-2.1607
204	A	G	-1.8898
205	D	G	-2.4566
206	Y	G	0.0000
207	E	G	-3.4498
208	K	G	-3.4065
209	H	G	-2.5476
210	K	G	-2.3502
211	V	G	-0.6866
212	Y	G	0.0000
213	A	G	-0.2674
214	C	G	0.0000
215	E	G	-0.6338
216	V	G	0.0000
217	T	G	-1.0716
218	Q	G	-1.1224
219	G	G	-0.8610
220	T	G	-0.4142
221	T	G	-0.2521
222	S	G	-0.3866
223	V	G	0.0347
224	T	G	-0.3033
225	K	G	-0.5559
226	S	G	-0.2517
227	F	G	-0.5220
228	N	G	-1.4948
229	R	G	-2.0512
230	G	G	-1.7931
231	E	G	-2.0606
232	C	G	-0.4090