Project name: 298

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCTASGYTNRLKCMGWFRQAPGKEREEIATISTGTGNTYYADSVKGRFTFSRDNSKNTLYLQMNSLRAEDTAVYYCAADVRPDGTTCHYNSGGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:39)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:40)

• Minimal score value: -3.8061
• Maximal score value: 1.0917
• Average score: -0.8773
• Total score value: -107.0254

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.6450
2	V	H	-0.3820
3	Q	H	-1.0569
4	L	H	0.0000
5	V	H	0.3825
6	E	H	-0.1495
7	S	H	-0.6431
8	G	H	-0.9445
9	G	H	-0.5316
11	G	H	0.2408
12	L	H	1.0917
13	V	H	0.0021
14	Q	H	-1.3372
15	P	H	-1.5843
16	G	H	-1.4066
17	G	H	-0.9540
18	S	H	-1.0799
19	L	H	-0.5719
20	R	H	-1.4309
21	L	H	0.0000
22	S	H	0.0000
23	C	H	0.0000
24	T	H	-0.4516
25	A	H	0.0000
26	S	H	-0.7725
27	G	H	-1.1266
28	Y	H	-1.0746
29	T	H	-1.2313
30	N	H	-2.5092
35	R	H	-2.6233
36	L	H	0.0000
37	K	H	-1.6002
38	C	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	-0.8031
43	R	H	0.0000
44	Q	H	-2.1038
45	A	H	-1.8560
46	P	H	-1.2632
47	G	H	-1.9803
48	K	H	-3.4225
49	E	H	-3.8061
50	R	H	-3.2398
51	E	H	-2.3890
52	E	H	-1.1980
53	I	H	0.0000
54	A	H	0.0000
55	T	H	0.1552
56	I	H	0.0000
57	S	H	-0.9164
58	T	H	-1.5465
59	G	H	-1.1731
62	T	H	-0.7477
63	G	H	-0.8419
64	N	H	-1.0194
65	T	H	0.0467
66	Y	H	0.6786
67	Y	H	-0.3284
68	A	H	-1.1941
69	D	H	-2.3178
70	S	H	-1.7009
71	V	H	0.0000
72	K	H	-2.3809
74	G	H	-1.7276
75	R	H	-1.4618
76	F	H	0.0000
77	T	H	-0.6433
78	F	H	0.0000
79	S	H	-0.6965
80	R	H	-1.3446
81	D	H	-1.9760
82	N	H	-2.5725
83	S	H	-1.9664
84	K	H	-2.6495
85	N	H	-2.2065
86	T	H	-1.2506
87	L	H	0.0000
88	Y	H	-0.4358
89	L	H	0.0000
90	Q	H	-0.9895
91	M	H	0.0000
92	N	H	-1.3218
93	S	H	-1.2533
94	L	H	0.0000
95	R	H	-2.1934
96	A	H	-1.6542
97	E	H	-2.1963
98	D	H	0.0000
99	T	H	-0.6972
100	A	H	0.0000
101	V	H	-0.1940
102	Y	H	0.0000
103	Y	H	-0.4407
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	D	H	0.0000
108	V	H	-0.4452
109	R	H	-1.0270
110	P	H	-1.3625
111	D	H	-2.1668
111A	G	H	-1.4198
112A	T	H	-1.0907
112	T	H	-0.5785
113	C	H	-0.5070
114	H	H	-0.9904
115	Y	H	-0.8135
116	N	H	-1.4295
117	S	H	-0.8265
118	G	H	-0.9477
119	G	H	-0.7748
120	Q	H	-1.1940
121	G	H	-0.6224
122	T	H	-0.5812
123	Q	H	-0.4865
124	V	H	0.0000
125	T	H	-0.1335
126	V	H	0.0000
127	S	H	-0.4638
128	S	H	-0.5546