Project name: 9582ae0e925f4df

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGGGFASGSYYMGWFRQAPGKGRELVAWISGSGGTETYYADSVKGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAASSSTPRDVFDTSDYDYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:53)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:54)

• Minimal score value: -2.7324
• Maximal score value: 1.2195
• Average score: -0.7607
• Total score value: -97.3703

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.5467
2	V	A	0.0000
3	Q	A	-1.3732
4	L	A	0.0000
5	V	A	1.2195
6	E	A	0.0000
7	S	A	-0.5264
8	G	A	-1.1307
9	G	A	-0.8024
10	G	A	-0.0905
11	L	A	0.9199
12	V	A	0.0000
13	Q	A	-1.4261
14	P	A	-1.6252
15	G	A	-1.4275
16	G	A	-0.9674
17	S	A	-1.2337
18	L	A	-0.9332
19	R	A	-2.1339
20	L	A	0.0000
21	S	A	-0.3133
22	C	A	0.0000
23	A	A	-0.0210
24	A	A	0.0000
25	S	A	-1.0903
26	G	A	-1.4790
27	G	A	-1.4088
28	G	A	-1.0483
29	F	A	0.0000
30	A	A	-1.0817
31	S	A	-0.7052
32	G	A	0.0000
33	S	A	-0.5125
34	Y	A	-0.3345
35	Y	A	-0.0236
36	M	A	0.0000
37	G	A	0.0000
38	W	A	0.0000
39	F	A	0.0000
40	R	A	0.0000
41	Q	A	-1.7774
42	A	A	-1.6657
43	P	A	-1.1942
44	G	A	-1.6644
45	K	A	-2.7324
46	G	A	-2.3213
47	R	A	-2.1602
48	E	A	-1.8868
49	L	A	0.0000
50	V	A	0.0000
51	A	A	0.0000
52	W	A	0.0000
53	I	A	0.0000
54	S	A	0.0000
55	G	A	0.0000
56	S	A	-0.7556
57	G	A	-1.1535
58	G	A	-1.1484
59	T	A	-1.2283
60	E	A	-1.8766
61	T	A	-0.6599
62	Y	A	-0.1293
63	Y	A	-0.5881
64	A	A	-1.0865
65	D	A	-2.3468
66	S	A	-1.6989
67	V	A	0.0000
68	K	A	-2.4292
69	G	A	-1.6404
70	R	A	0.0000
71	F	A	0.0000
72	T	A	-0.7522
73	I	A	0.0000
74	S	A	-0.6667
75	R	A	-1.0741
76	D	A	-1.7262
77	N	A	-1.6138
78	A	A	-1.3462
79	K	A	-2.3159
80	R	A	-1.8845
81	M	A	-0.9254
82	V	A	0.0000
83	Y	A	-0.6138
84	L	A	0.0000
85	Q	A	-1.2504
86	M	A	0.0000
87	N	A	-1.3587
88	S	A	-1.1805
89	L	A	0.0000
90	R	A	-2.2125
91	A	A	-1.7262
92	E	A	-2.2081
93	D	A	0.0000
94	T	A	-0.8611
95	A	A	0.0000
96	V	A	-0.5091
97	Y	A	0.0000
98	Y	A	-0.2835
99	C	A	0.0000
100	A	A	0.0000
101	A	A	0.0000
102	S	A	0.0000
103	S	A	-0.8604
104	S	A	-0.7911
105	T	A	-0.7831
106	P	A	0.0000
107	R	A	-2.4068
108	D	A	-1.7996
109	V	A	-0.2856
110	F	A	0.3715
111	D	A	-0.9307
112	T	A	-0.8251
113	S	A	-0.9414
114	D	A	-1.3190
115	Y	A	0.0000
116	D	A	-1.8861
117	Y	A	-1.0777
118	W	A	-0.1865
119	G	A	-0.0750
120	Q	A	-0.8307
121	G	A	-0.5017
122	T	A	-0.6784
123	Q	A	-1.0119
124	V	A	0.0000
125	T	A	-0.3581
126	V	A	0.0000
127	S	A	-0.8437
128	S	A	-0.6007