Project name: 97c2fae53cffad2

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGKYASNPMGWFRQAPGKGRELVAAILGGDGGSTYYPDSVEGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAAATLKGDDLASRLAALRDVSNWDFWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:30)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:31)

• Minimal score value: -2.9466
• Maximal score value: 0.8949
• Average score: -0.9102
• Total score value: -121.0529

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.7079
2	V	A	-2.0860
3	Q	A	-1.5131
4	L	A	0.0000
5	V	A	0.7121
6	E	A	0.0000
7	S	A	-0.5879
8	G	A	-0.8419
9	G	A	-0.7355
10	G	A	-0.0685
11	L	A	0.8949
12	V	A	0.0000
13	Q	A	-1.3481
14	P	A	-1.5147
15	G	A	-1.3723
16	G	A	-0.9473
17	S	A	-1.1809
18	L	A	-0.8171
19	R	A	-1.6909
20	L	A	0.0000
21	S	A	-0.2702
22	C	A	0.0000
23	A	A	-0.4525
24	A	A	0.0000
25	S	A	-1.7835
26	G	A	-2.3322
27	K	A	-2.4946
28	Y	A	0.0000
29	A	A	-1.3922
30	S	A	-0.8971
31	N	A	-0.4398
32	P	A	0.0000
33	M	A	0.0000
34	G	A	0.0000
35	W	A	0.0000
36	F	A	0.0000
37	R	A	0.0000
38	Q	A	-1.6474
39	A	A	-1.6231
40	P	A	-1.1727
41	G	A	-1.6396
42	K	A	-2.6652
43	G	A	-2.1050
44	R	A	-2.2571
45	E	A	-2.4916
46	L	A	0.0000
47	V	A	0.0000
48	A	A	0.0000
49	A	A	0.0000
50	I	A	0.0000
51	L	A	-0.2292
52	G	A	-0.7466
53	G	A	-1.4548
54	D	A	-2.3839
55	G	A	-1.5644
56	G	A	-1.0800
57	S	A	-0.5331
58	T	A	-0.0500
59	Y	A	-0.2975
60	Y	A	-0.8958
61	P	A	-1.7803
62	D	A	-2.5697
63	S	A	-1.8544
64	V	A	0.0000
65	E	A	-2.7361
66	G	A	-1.8761
67	R	A	-1.6072
68	F	A	0.0000
69	T	A	-0.8147
70	I	A	0.0000
71	S	A	-0.6982
72	R	A	0.0000
73	D	A	-2.1813
74	N	A	-2.2555
75	A	A	-1.8302
76	K	A	-2.7763
77	R	A	-2.8937
78	M	A	-1.3570
79	V	A	0.0000
80	Y	A	-0.4019
81	L	A	0.0000
82	Q	A	-1.0663
83	M	A	0.0000
84	N	A	-1.3623
85	S	A	-1.2031
86	L	A	0.0000
87	R	A	-2.1415
88	A	A	-1.6790
89	E	A	-2.1995
90	D	A	0.0000
91	T	A	-0.8426
92	A	A	0.0000
93	V	A	-0.4615
94	Y	A	0.0000
95	Y	A	-0.2864
96	C	A	0.0000
97	A	A	0.0000
98	A	A	0.0000
99	A	A	0.0000
100	A	A	-0.8824
101	T	A	-0.4073
102	L	A	-0.6374
103	K	A	-1.7995
104	G	A	-2.2934
105	D	A	-2.9466
106	D	A	-2.3937
107	L	A	-0.0963
108	A	A	-0.3375
109	S	A	-1.5211
110	R	A	-1.9547
111	L	A	-0.6757
112	A	A	-0.9406
113	A	A	0.0000
114	L	A	0.0000
115	R	A	-2.5942
116	D	A	-1.8785
117	V	A	-1.0208
118	S	A	-0.8247
119	N	A	-1.1452
120	W	A	0.0000
121	D	A	-1.6829
122	F	A	-0.9682
123	W	A	-0.2336
124	G	A	-0.1927
125	Q	A	-0.7876
126	G	A	-0.5595
127	T	A	0.0000
128	Q	A	-0.9970
129	V	A	0.0000
130	T	A	-0.3576
131	V	A	0.0000
132	S	A	-0.7632
133	S	A	-0.5820