Project name: 184

Chain sequence(s)	H: QVQLQESGGDSVQAGGSLRLSCAASGSTYSSNCMGWFRQAPGKEREEVASMSIRSGRTYYSDSVKGRFTISHDGSKNTLYLQMNSLKAEDTAMYYCAAAYGGSRCDYNYRGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:00)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:01)

• Minimal score value: -3.744
• Maximal score value: 1.3577
• Average score: -1.0212
• Total score value: -122.5495

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.3640
2	V	H	-1.1711
3	Q	H	-1.5532
4	L	H	0.0000
5	Q	H	-2.0006
6	E	H	-1.4935
7	S	H	-1.3951
8	G	H	-1.4593
9	G	H	-1.6766
11	D	H	-2.2807
12	S	H	-1.3091
13	V	H	-1.0757
14	Q	H	-1.5566
15	A	H	-1.5666
16	G	H	-1.2879
17	G	H	-1.0281
18	S	H	-1.0342
19	L	H	-1.1066
20	R	H	-1.7836
21	L	H	0.0000
22	S	H	-0.7912
23	C	H	0.0000
24	A	H	-1.0177
25	A	H	-0.9337
26	S	H	-1.1067
27	G	H	-0.7782
28	S	H	-0.2518
29	T	H	0.2846
30	Y	H	1.3577
35	S	H	0.0000
36	S	H	0.0000
37	N	H	-0.0411
38	C	H	-0.6201
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	-0.7213
43	R	H	0.0000
44	Q	H	-2.0590
45	A	H	-1.9176
46	P	H	-1.3701
47	G	H	-1.9556
48	K	H	-3.4460
49	E	H	-3.7440
50	R	H	-3.0986
51	E	H	-3.0023
52	E	H	-1.2713
53	V	H	0.0000
54	A	H	0.0000
55	S	H	0.0000
56	M	H	0.0000
57	S	H	-1.0007
58	I	H	-1.1048
59	R	H	-2.1847
62	S	H	-1.6888
63	G	H	-1.8434
64	R	H	-2.0366
65	T	H	-0.3494
66	Y	H	0.5297
67	Y	H	-0.2491
68	S	H	-1.2976
69	D	H	-2.3746
70	S	H	-1.8354
71	V	H	0.0000
72	K	H	-2.4650
74	G	H	-1.7588
75	R	H	-1.6767
76	F	H	0.0000
77	T	H	-0.6319
78	I	H	0.0000
79	S	H	-0.5115
80	H	H	-0.8419
81	D	H	-1.4002
82	G	H	-1.6896
83	S	H	-1.5431
84	K	H	-2.3665
85	N	H	-1.6385
86	T	H	-1.2603
87	L	H	0.0000
88	Y	H	-0.3875
89	L	H	0.0000
90	Q	H	-0.9694
91	M	H	0.0000
92	N	H	-1.2614
93	S	H	-1.1711
94	L	H	0.0000
95	K	H	-2.2743
96	A	H	-1.6880
97	E	H	-2.2500
98	D	H	0.0000
99	T	H	-1.1216
100	A	H	0.0000
101	M	H	-0.3072
102	Y	H	0.0000
103	Y	H	-0.9138
104	C	H	0.0000
105	A	H	0.0000
106	A	H	0.0000
107	A	H	0.0000
108	Y	H	0.5857
109	G	H	-0.7287
110	G	H	-1.0401
111	S	H	-1.4232
112	R	H	-2.3317
113	C	H	-1.6737
114	D	H	-2.3005
115	Y	H	-1.5828
116	N	H	-1.5241
117	Y	H	-1.3199
118	R	H	-2.3455
119	G	H	0.0000
120	Q	H	-2.0103
121	G	H	-1.2189
122	T	H	-1.1619
123	Q	H	-1.1870
124	V	H	0.0000
125	T	H	-1.2106
126	V	H	0.0000
127	S	H	-1.0698
128	S	H	-0.8163