Project name: FEFEFEGGKGH12

Chain sequence(s)	A: FEFEFEGGKGH; C: FEFEFEGGKGH; B: FEFEFEGGKGH; E: FEFEFEGGKGH; D: FEFEFEGGKGH; G: FEFEFEGGKGH; F: FEFEFEGGKGH; I: FEFEFEGGKGH; H: FEFEFEGGKGH; K: FEFEFEGGKGH; J: FEFEFEGGKGH; L: FEFEFEGGKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:06:36)
[INFO]       Main:     Simulation completed successfully.                                          (00:06:40)

• Minimal score value: -4.3561
• Maximal score value: 0.9985
• Average score: -2.4239
• Total score value: -319.9511

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	0.2366
2	E	A	-2.3122
3	F	A	-2.2509
4	E	A	-4.0634
5	F	A	-3.1071
6	E	A	-3.5749
7	G	A	0.0000
8	G	A	-2.5906
9	K	A	-2.5520
10	G	A	-2.3573
11	H	A	-2.1391
1	F	B	0.7954
2	E	B	-2.1516
3	F	B	-2.2409
4	E	B	-4.0691
5	F	B	-2.9007
6	E	B	-3.7622
7	G	B	-2.7116
8	G	B	-2.8512
9	K	B	-3.0121
10	G	B	-2.5746
11	H	B	-2.4283
1	F	C	0.6463
2	E	C	-2.1584
3	F	C	-2.2159
4	E	C	-4.1558
5	F	C	-3.4103
6	E	C	-4.1450
7	G	C	-2.9195
8	G	C	-3.1103
9	K	C	-3.2780
10	G	C	-2.7726
11	H	C	-2.3719
1	F	D	0.2027
2	E	D	-2.4570
3	F	D	0.0000
4	E	D	-4.3150
5	F	D	-3.3888
6	E	D	-4.2728
7	G	D	-2.9297
8	G	D	-2.8895
9	K	D	-2.8113
10	G	D	-2.4197
11	H	D	-2.1219
1	F	E	0.0780
2	E	E	-2.5621
3	F	E	0.0000
4	E	E	-4.2975
5	F	E	-3.3659
6	E	E	-4.0763
7	G	E	-2.7954
8	G	E	-2.7034
9	K	E	-2.6364
10	G	E	-2.2719
11	H	E	-2.0560
1	F	F	0.2868
2	E	F	-2.3894
3	F	F	-2.4300
4	E	F	-4.2555
5	F	F	-3.3282
6	E	F	-3.8410
7	G	F	0.0000
8	G	F	-2.6815
9	K	F	-2.3491
10	G	F	-2.1027
11	H	F	-2.0006
1	F	G	0.9366
2	E	G	-2.0058
3	F	G	0.0000
4	E	G	-4.1483
5	F	G	-3.3404
6	E	G	-4.0797
7	G	G	-2.7975
8	G	G	-2.8505
9	K	G	-2.6923
10	G	G	-2.4434
11	H	G	-2.2032
1	F	H	0.9985
2	E	H	-1.9027
3	F	H	-2.0718
4	E	H	-4.1481
5	F	H	-3.4278
6	E	H	-4.0668
7	G	H	0.0000
8	G	H	-3.2610
9	K	H	-3.2800
10	G	H	-2.7558
11	H	H	-2.3959
1	F	I	0.4287
2	E	I	-2.1868
3	F	I	-2.2318
4	E	I	-4.2088
5	F	I	-3.3442
6	E	I	-4.3518
7	G	I	0.0000
8	G	I	-3.2739
9	K	I	-3.5175
10	G	I	-2.7999
11	H	I	-2.4787
1	F	J	0.2517
2	E	J	-2.3615
3	F	J	-2.3471
4	E	J	-4.2471
5	F	J	-3.3419
6	E	J	-4.3117
7	G	J	-3.0632
8	G	J	-3.0346
9	K	J	-3.0098
10	G	J	-2.5136
11	H	J	-2.1490
1	F	K	0.6360
2	E	K	-2.2462
3	F	K	0.0000
4	E	K	-4.3561
5	F	K	-3.3042
6	E	K	-4.2733
7	G	K	-2.8761
8	G	K	-2.7510
9	K	K	-2.6137
10	G	K	-2.2703
11	H	K	-2.0640
1	F	L	0.8293
2	E	L	-2.0861
3	F	L	0.0000
4	E	L	-4.0667
5	F	L	-3.4748
6	E	L	-4.0043
7	G	L	0.0000
8	G	L	-2.5941
9	K	L	-2.4583
10	G	L	-2.2368
11	H	L	-2.0217