Project name: 9c0ab0f88d29653

Chain sequence(s)	A: QVQLQESGPGLVKPSETLSLTCTVSGGSVSSGDYYWTWIRQSPGKGLEWIGHIYYSGNTNYNPSLKSRLTISIDTSKTQFSLKLSSVTAADTAIYYCVRDRVTGAFDIWGQGTMVTVSSGGGGSGGGGSGGGGSDIQMTQSPSSLSASVGDRVTITCQASQDISNYLNWYQQKPGKAPKLLIYDASNLETGVPSRFSGSGSGTDFTFTISSLQPEDIATYFCQHFDHLPLAFGGGTKVEI
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:35)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:37)

• Minimal score value: -2.8893
• Maximal score value: 1.2709
• Average score: -0.6468
• Total score value: -155.222

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.6279
2	V	A	-1.2847
3	Q	A	-1.9912
4	L	A	0.0000
5	Q	A	-1.8725
6	E	A	0.0000
7	S	A	-0.7778
8	G	A	-0.5271
9	P	A	-0.1283
10	G	A	0.1842
11	L	A	0.6441
12	V	A	0.0000
13	K	A	-1.9717
14	P	A	-1.4687
15	S	A	-1.2699
16	E	A	-1.6091
17	T	A	-1.2147
18	L	A	0.0000
19	S	A	-0.8099
20	L	A	0.0000
21	T	A	-0.6134
22	C	A	0.0000
23	T	A	-1.1714
24	V	A	0.0000
25	S	A	-1.4667
26	G	A	-1.3358
27	G	A	-1.0502
28	S	A	-0.6383
29	V	A	0.0000
30	S	A	-0.3306
31	S	A	-0.6345
32	G	A	-0.6384
33	D	A	-1.2539
34	Y	A	-0.0691
35	Y	A	0.2987
36	W	A	0.0000
37	T	A	0.0000
38	W	A	0.0000
39	I	A	0.0000
40	R	A	0.0000
41	Q	A	-0.6660
42	S	A	-0.8078
43	P	A	-0.9141
44	G	A	-1.4634
45	K	A	-2.2821
46	G	A	-1.3889
47	L	A	0.0000
48	E	A	-0.9130
49	W	A	0.0000
50	I	A	0.0000
51	G	A	0.0000
52	H	A	0.0000
53	I	A	0.0000
54	Y	A	0.0201
55	Y	A	0.1036
56	S	A	-0.3122
57	G	A	-0.7649
58	N	A	-1.3384
59	T	A	-0.7553
60	N	A	-0.7756
61	Y	A	-0.5889
62	N	A	-0.6769
63	P	A	-1.0642
64	S	A	-1.0149
65	L	A	0.0000
66	K	A	-2.0772
67	S	A	-1.2996
68	R	A	-1.3378
69	L	A	0.0000
70	T	A	-0.9304
71	I	A	0.0000
72	S	A	-0.4953
73	I	A	-0.4893
74	D	A	-1.2127
75	T	A	-1.0064
76	S	A	-1.3130
77	K	A	-2.1154
78	T	A	-1.3783
79	Q	A	-1.2356
80	F	A	0.0000
81	S	A	-0.5216
82	L	A	0.0000
83	K	A	-1.2637
84	L	A	0.0000
85	S	A	-0.9715
86	S	A	-0.9901
87	V	A	0.0000
88	T	A	-0.7176
89	A	A	-0.3608
90	A	A	-0.0542
91	D	A	0.0000
92	T	A	0.2417
93	A	A	0.0000
94	I	A	0.5406
95	Y	A	0.0000
96	Y	A	0.0000
97	C	A	0.0000
98	V	A	0.0000
99	R	A	-0.2514
100	D	A	0.0000
101	R	A	-0.0199
102	V	A	1.0419
103	T	A	0.4529
104	G	A	0.3600
105	A	A	0.0000
106	F	A	0.0000
107	D	A	-0.5150
108	I	A	-0.5085
109	W	A	-0.9379
110	G	A	0.0000
111	Q	A	-1.8935
112	G	A	-0.9144
113	T	A	-0.2564
114	M	A	0.5713
115	V	A	0.0000
116	T	A	0.2157
117	V	A	0.0000
118	S	A	-0.7023
119	S	A	-1.0551
120	G	A	-1.3841
121	G	A	-1.1230
122	G	A	-1.1766
123	G	A	-1.1883
124	S	A	-1.0134
125	G	A	-1.2084
126	G	A	-1.2121
127	G	A	-1.2039
128	G	A	-1.2211
129	S	A	-1.0780
130	G	A	-1.2295
131	G	A	-1.4794
132	G	A	-1.3182
133	G	A	-1.4287
134	S	A	-1.5177
135	D	A	-2.0901
136	I	A	-1.7883
137	Q	A	-1.8686
138	M	A	0.0000
139	T	A	-1.0875
140	Q	A	-0.7713
141	S	A	-0.7370
142	P	A	-0.6626
143	S	A	-0.9266
144	S	A	-1.3142
145	L	A	-0.6556
146	S	A	-0.4917
147	A	A	-0.1904
148	S	A	-0.0520
149	V	A	0.3034
150	G	A	-0.9406
151	D	A	-1.7495
152	R	A	-2.4263
153	V	A	0.0000
154	T	A	-0.6557
155	I	A	0.0000
156	T	A	-0.7687
157	C	A	0.0000
158	Q	A	-2.3445
159	A	A	0.0000
160	S	A	-2.1001
161	Q	A	-2.8893
162	D	A	-2.8884
163	I	A	0.0000
164	S	A	-1.3374
165	N	A	-1.0462
166	Y	A	-0.1757
167	L	A	0.0000
168	N	A	0.0000
169	W	A	0.0000
170	Y	A	0.0000
171	Q	A	0.0000
172	Q	A	-1.2644
173	K	A	-1.6795
174	P	A	-1.0730
175	G	A	-1.5908
176	K	A	-2.3754
177	A	A	-1.5254
178	P	A	0.0000
179	K	A	-1.4369
180	L	A	0.0000
181	L	A	0.0000
182	I	A	0.0000
183	Y	A	-0.1198
184	D	A	-0.5334
185	A	A	0.0000
186	S	A	-0.6887
187	N	A	-0.6898
188	L	A	-0.0602
189	E	A	-0.3443
190	T	A	-0.3008
191	G	A	-0.4428
192	V	A	-0.3081
193	P	A	-0.3771
194	S	A	-0.4408
195	R	A	-0.7559
196	F	A	0.0000
197	S	A	-0.4255
198	G	A	-0.4329
199	S	A	-0.9654
200	G	A	-1.2967
201	S	A	-1.4942
202	G	A	-1.9142
203	T	A	-2.4111
204	D	A	-2.7630
205	F	A	0.0000
206	T	A	-0.7921
207	F	A	0.0000
208	T	A	-0.6172
209	I	A	0.0000
210	S	A	-1.3546
211	S	A	-1.2394
212	L	A	0.0000
213	Q	A	-0.6086
214	P	A	-0.7349
215	E	A	-1.7624
216	D	A	0.0000
217	I	A	-0.6349
218	A	A	0.0000
219	T	A	0.0000
220	Y	A	0.0000
221	F	A	0.0000
222	C	A	0.0000
223	Q	A	0.0000
224	H	A	0.0000
225	F	A	-0.0032
226	D	A	-0.8576
227	H	A	-0.7679
228	L	A	0.1339
229	P	A	-0.2834
230	L	A	0.0000
231	A	A	-0.4999
232	F	A	-0.2599
233	G	A	0.0000
234	G	A	-1.1613
235	G	A	0.0000
236	T	A	0.0000
237	K	A	-2.2719
238	V	A	0.0000
239	E	A	-0.9977
240	I	A	1.2709