Project name: 9c3382ada0e2b09

Chain sequence(s)	A: AGSITTLPALPEDGGSGAFPPGHFKDPKRLYCKNGGFFLRIHPDGRVDGVREKSDPHIKLQLQAEERGVVSIKGVCANRYLAMKEDGRLLASKCVTDECFFFERLESNNYNTYRSRKYTSWYVALKRTGQYKLGSKTGPGQKAILFLPMSAKS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:25)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:26)

• Minimal score value: -3.6608
• Maximal score value: 1.9489
• Average score: -0.8773
• Total score value: -134.2194

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	0.0404
2	G	A	-0.0204
3	S	A	0.5232
4	I	A	1.9489
5	T	A	1.1617
6	T	A	1.1652
7	L	A	1.8961
8	P	A	0.9063
9	A	A	0.7195
10	L	A	0.8225
11	P	A	-1.0778
12	E	A	-2.6464
13	D	A	-2.9431
14	G	A	-2.4246
15	G	A	-1.8177
16	S	A	-1.2331
17	G	A	-0.1832
18	A	A	-0.1414
19	F	A	0.5288
20	P	A	-0.0873
21	P	A	-0.7580
22	G	A	-1.3425
23	H	A	-1.6754
24	F	A	-1.5006
25	K	A	-2.5220
26	D	A	-2.2578
27	P	A	-1.5673
28	K	A	-1.0835
29	R	A	-0.8393
30	L	A	0.0000
31	Y	A	-0.1335
32	C	A	0.0000
33	K	A	-1.4344
34	N	A	0.0000
35	G	A	-1.6656
36	G	A	-1.2124
37	F	A	0.0000
38	F	A	0.0000
39	L	A	0.0000
40	R	A	-1.1679
41	I	A	0.0000
42	H	A	-1.6035
43	P	A	-1.8692
44	D	A	-2.6567
45	G	A	0.0000
46	R	A	-2.4315
47	V	A	0.0000
48	D	A	-1.0154
49	G	A	-1.2353
50	V	A	-1.7935
51	R	A	-3.1460
52	E	A	-3.6295
53	K	A	-3.3107
54	S	A	-2.0860
55	D	A	-1.9177
56	P	A	-0.9025
57	H	A	-0.7295
58	I	A	0.0000
59	K	A	-1.1428
60	L	A	0.0000
61	Q	A	-1.1362
62	L	A	0.0000
63	Q	A	-1.8111
64	A	A	-2.1545
65	E	A	-3.2374
66	E	A	-3.6608
67	R	A	-3.0436
68	G	A	-1.8194
69	V	A	0.0000
70	V	A	0.0000
71	S	A	0.0000
72	I	A	0.0000
73	K	A	-0.6728
74	G	A	0.0000
75	V	A	0.0587
76	C	A	0.2313
77	A	A	-1.2916
78	N	A	-1.4732
79	R	A	-1.5269
80	Y	A	-0.2845
81	L	A	0.0000
82	A	A	0.0000
83	M	A	0.0000
84	K	A	-2.4876
85	E	A	-3.2589
86	D	A	-2.9462
87	G	A	0.0000
88	R	A	-2.1306
89	L	A	0.0000
90	L	A	-0.8547
91	A	A	0.0000
92	S	A	-0.9856
93	K	A	-1.7193
94	C	A	0.3365
95	V	A	0.9831
96	T	A	0.0319
97	D	A	-1.4022
98	E	A	-1.3242
99	C	A	0.0000
100	F	A	0.0000
101	F	A	0.0000
102	F	A	-0.9363
103	E	A	-0.8598
104	R	A	-0.8282
105	L	A	0.0214
106	E	A	-1.1473
107	S	A	-1.2625
108	N	A	-1.8287
109	N	A	-1.6856
110	Y	A	-0.9452
111	N	A	-0.3977
112	T	A	0.0000
113	Y	A	0.0000
114	R	A	-0.8322
115	S	A	0.0000
116	R	A	-1.5324
117	K	A	-2.2694
118	Y	A	-1.4236
119	T	A	-0.6851
120	S	A	-0.6862
121	W	A	-0.5728
122	Y	A	-0.3586
123	V	A	0.0000
124	A	A	0.0000
125	L	A	0.0000
126	K	A	-2.1030
127	R	A	-2.6860
128	T	A	-1.4274
129	G	A	0.0000
130	Q	A	-1.3005
131	Y	A	-1.1294
132	K	A	-1.2812
133	L	A	-1.2420
134	G	A	0.0000
135	S	A	-1.6490
136	K	A	-1.7951
137	T	A	-1.2679
138	G	A	-1.0124
139	P	A	-0.8802
140	G	A	-1.1939
141	Q	A	-1.7412
142	K	A	-2.5392
143	A	A	0.0000
144	I	A	0.0000
145	L	A	0.0000
146	F	A	0.0000
147	L	A	0.3987
148	P	A	0.0994
149	M	A	-0.0638
150	S	A	-0.9627
151	A	A	0.0000
152	K	A	-2.0494
153	S	A	-1.0908