| Chain sequence(s) |
A: MKRKAFASLVASVVAAATVTMPTASFAAGLGNSSGLTDGLSAPRASISPTDKVDLKSAQETDETGVDKYIRGLKYDPSGVLAVKGESIENVPVTKDQLKDGTYTVFKHERKSFNNLRSDISAFDANNAHVYPGALVLANKDLAKGSPTSIGIARAPQTVSVDLPGLVDGKNKVVINNPTKSSVTQGLNGLLDGWIQRNSKYPDHAAKISYDETMVTSKRQLEAKLGLGFEKVSAKLNVDFDAIHKRERQVAIASFKQIYYTASVDTPTSPHSVFGPNVTAQDLKDRGVNNKNPLGYISSVSYGRQIFVKLETTSTSNDVQAAFSGLFKAKFGNLSTEFKAKYADILNKTRATVYAVGGSARGGVEVATGNIDALKKIIKEESTYSTKVPAVPVSYAVNFLKDNQLAAVRSSGDYIETTATTYKSGEITFRHGGGYVAKFRLKWDEISYDPQGKEIRTPKTWSGNWAARTLGFRETIQLPANARNIHVEAGEATGLAWDPWWTVINKKNLPLVPHREIVLKGTTLNPWVEDNVKS
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | LN524A,LF225A,SF314A,VI232A,SA233A,GS357A,NS90A,VP93A |
| Energy difference between WT (input) and mutated protein (by FoldX) | 3.74291 kcal/mol
CAUTION: Your mutation/s can destabilize the protein structure |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:00)
[INFO] FoldX: Building mutant model (00:13:08)
[INFO] FoldX: Starting FoldX energy minimalization (00:15:05)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:21:31)
[INFO] Main: Simulation completed successfully. (00:21:39)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | -0.1528 | |
| 2 | K | A | -2.5206 | |
| 3 | R | A | -3.0533 | |
| 4 | K | A | -2.4860 | |
| 5 | A | A | -0.5191 | |
| 6 | F | A | 1.4936 | |
| 7 | A | A | 1.3545 | |
| 8 | S | A | 1.5300 | |
| 9 | L | A | 2.5384 | |
| 10 | V | A | 2.6564 | |
| 11 | A | A | 1.9043 | |
| 12 | S | A | 1.8351 | |
| 13 | V | A | 2.7823 | |
| 14 | V | A | 2.6323 | |
| 15 | A | A | 1.4141 | |
| 16 | A | A | 0.9939 | |
| 17 | A | A | 0.7455 | |
| 18 | T | A | 0.9354 | |
| 19 | V | A | 1.9626 | |
| 20 | T | A | 1.2143 | |
| 21 | M | A | 1.3225 | |
| 22 | P | A | 0.3863 | |
| 23 | T | A | 0.2290 | |
| 24 | A | A | 0.4329 | |
| 25 | S | A | 0.7293 | |
| 26 | F | A | 1.8854 | |
| 27 | A | A | 0.8851 | |
| 28 | A | A | 0.6490 | |
| 29 | G | A | 0.2865 | |
| 30 | L | A | 0.8290 | |
| 31 | G | A | -0.4590 | |
| 32 | N | A | -1.3523 | |
| 33 | S | A | -1.2035 | |
| 34 | S | A | -0.4995 | |
| 35 | G | A | 0.1766 | |
| 36 | L | A | 0.7863 | |
| 37 | T | A | -0.2863 | |
| 38 | D | A | -1.4305 | |
| 39 | G | A | -0.6445 | |
| 40 | L | A | 0.8597 | |
| 41 | S | A | 0.4512 | |
| 42 | A | A | -0.3179 | |
| 43 | P | A | -1.1444 | |
| 44 | R | A | -1.9672 | |
| 45 | A | A | -0.6211 | |
| 46 | S | A | 0.3571 | |
| 47 | I | A | 1.7666 | |
| 48 | S | A | 0.3585 | |
| 49 | P | A | -0.5516 | |
| 50 | T | A | -1.3267 | |
| 51 | D | A | -2.4561 | |
| 52 | K | A | -2.0047 | |
| 53 | V | A | -0.2479 | |
| 54 | D | A | -1.3734 | |
| 55 | L | A | -0.0298 | |
| 56 | K | A | -1.5057 | |
| 57 | S | A | -1.4219 | |
| 58 | A | A | -1.2627 | |
| 59 | Q | A | -2.7040 | |
| 60 | E | A | -3.2125 | |
| 61 | T | A | -2.6258 | |
| 62 | D | A | -3.6883 | |
| 63 | E | A | -3.5629 | |
| 64 | T | A | -2.1476 | |
| 65 | G | A | -1.8972 | |
| 66 | V | A | 0.0000 | |
| 67 | D | A | 0.0000 | |
| 68 | K | A | -2.8967 | |
| 69 | Y | A | -1.8161 | |
| 70 | I | A | 0.0000 | |
| 71 | R | A | -2.1766 | |
| 72 | G | A | -1.7681 | |
| 73 | L | A | 0.0000 | |
| 74 | K | A | -2.7422 | |
| 75 | Y | A | -2.2524 | |
| 76 | D | A | -2.4361 | |
| 77 | P | A | -1.1171 | |
| 78 | S | A | -0.7728 | |
| 79 | G | A | -1.1773 | |
| 80 | V | A | -1.3230 | |
| 81 | L | A | 0.0000 | |
| 82 | A | A | -1.1356 | |
| 83 | V | A | -1.6813 | |
| 84 | K | A | -2.3367 | |
| 85 | G | A | -1.8555 | |
| 86 | E | A | -2.0662 | |
| 87 | S | A | -1.6688 | |
| 88 | I | A | -1.3032 | |
| 89 | E | A | -2.0348 | |
| 90 | S | A | -0.8987 | mutated: NS90A |
| 91 | V | A | -0.7821 | |
| 92 | P | A | -0.9738 | |
| 93 | P | A | -1.4634 | mutated: VP93A |
| 94 | T | A | -2.2284 | |
| 95 | K | A | -2.4265 | |
| 96 | D | A | -1.6983 | |
| 97 | Q | A | -1.3467 | |
| 98 | L | A | -0.8483 | |
| 99 | K | A | -2.4432 | |
| 100 | D | A | -2.8751 | |
| 101 | G | A | -1.9726 | |
| 102 | T | A | -1.6778 | |
| 103 | Y | A | 0.0000 | |
| 104 | T | A | -0.8300 | |
| 105 | V | A | 0.0000 | |
| 106 | F | A | -1.3644 | |
| 107 | K | A | -2.1412 | |
| 108 | H | A | -2.1410 | |
| 109 | E | A | -3.0373 | |
| 110 | R | A | -2.8858 | |
| 111 | K | A | -1.9101 | |
| 112 | S | A | -1.2473 | |
| 113 | F | A | -0.8941 | |
| 114 | N | A | -1.6115 | |
| 115 | N | A | -1.0125 | |
| 116 | L | A | -0.1005 | |
| 117 | R | A | -0.7887 | |
| 118 | S | A | -0.7606 | |
| 119 | D | A | -1.7022 | |
| 120 | I | A | 0.0000 | |
| 121 | S | A | -0.8159 | |
| 122 | A | A | 0.0000 | |
| 123 | F | A | 0.0000 | |
| 124 | D | A | -2.0067 | |
| 125 | A | A | -1.1769 | |
| 126 | N | A | -1.8688 | |
| 127 | N | A | -1.4163 | |
| 128 | A | A | -0.9370 | |
| 129 | H | A | -0.8312 | |
| 130 | V | A | 0.0000 | |
| 131 | Y | A | -0.2030 | |
| 132 | P | A | 0.0000 | |
| 133 | G | A | 0.0000 | |
| 134 | A | A | 0.0000 | |
| 135 | L | A | 0.0000 | |
| 136 | V | A | 0.0000 | |
| 137 | L | A | 0.0000 | |
| 138 | A | A | 0.0000 | |
| 139 | N | A | -1.8393 | |
| 140 | K | A | -2.5472 | |
| 141 | D | A | -2.5507 | |
| 142 | L | A | 0.0000 | |
| 143 | A | A | 0.0000 | |
| 144 | K | A | -1.5185 | |
| 145 | G | A | 0.0000 | |
| 146 | S | A | -1.3376 | |
| 147 | P | A | 0.0000 | |
| 148 | T | A | -0.7933 | |
| 149 | S | A | -0.4040 | |
| 150 | I | A | 0.0000 | |
| 151 | G | A | -0.5648 | |
| 152 | I | A | -0.1884 | |
| 153 | A | A | -0.5429 | |
| 154 | R | A | -1.0402 | |
| 155 | A | A | -0.9474 | |
| 156 | P | A | -0.8728 | |
| 157 | Q | A | 0.0000 | |
| 158 | T | A | -0.1445 | |
| 159 | V | A | 0.0000 | |
| 160 | S | A | -1.2312 | |
| 161 | V | A | 0.0000 | |
| 162 | D | A | -2.0128 | |
| 163 | L | A | 0.0000 | |
| 164 | P | A | -0.4280 | |
| 165 | G | A | -1.0128 | |
| 166 | L | A | -0.9895 | |
| 167 | V | A | 0.0843 | |
| 168 | D | A | -1.7313 | |
| 169 | G | A | -1.5993 | |
| 170 | K | A | -2.1984 | |
| 171 | N | A | -1.8576 | |
| 172 | K | A | -1.5256 | |
| 173 | V | A | 0.2137 | |
| 174 | V | A | 1.2131 | |
| 175 | I | A | 0.0000 | |
| 176 | N | A | -1.5500 | |
| 177 | N | A | -1.9026 | |
| 178 | P | A | 0.0000 | |
| 179 | T | A | -1.1046 | |
| 180 | K | A | -1.0330 | |
| 181 | S | A | -0.9546 | |
| 182 | S | A | -1.3641 | |
| 183 | V | A | 0.0000 | |
| 184 | T | A | -1.2508 | |
| 185 | Q | A | -1.9274 | |
| 186 | G | A | -0.9419 | |
| 187 | L | A | 0.0000 | |
| 188 | N | A | -2.3195 | |
| 189 | G | A | -1.8173 | |
| 190 | L | A | 0.0000 | |
| 191 | L | A | -1.2951 | |
| 192 | D | A | -2.3179 | |
| 193 | G | A | -1.9571 | |
| 194 | W | A | 0.0000 | |
| 195 | I | A | -0.9728 | |
| 196 | Q | A | -2.2838 | |
| 197 | R | A | -2.7599 | |
| 198 | N | A | -2.0635 | |
| 199 | S | A | -1.7128 | |
| 200 | K | A | -2.2392 | |
| 201 | Y | A | -1.1041 | |
| 202 | P | A | -1.1694 | |
| 203 | D | A | -1.9613 | |
| 204 | H | A | -1.0596 | |
| 205 | A | A | -0.5710 | |
| 206 | A | A | -0.3854 | |
| 207 | K | A | -0.7043 | |
| 208 | I | A | 1.2463 | |
| 209 | S | A | 0.4659 | |
| 210 | Y | A | 0.1546 | |
| 211 | D | A | -1.1039 | |
| 212 | E | A | -1.1481 | |
| 213 | T | A | -0.7213 | |
| 214 | M | A | -0.2875 | |
| 215 | V | A | 0.0000 | |
| 216 | T | A | 0.0000 | |
| 217 | S | A | -1.0102 | |
| 218 | K | A | -1.3517 | |
| 219 | R | A | -1.4086 | |
| 220 | Q | A | 0.0000 | |
| 221 | L | A | 0.0000 | |
| 222 | E | A | -1.0446 | |
| 223 | A | A | 0.0000 | |
| 224 | K | A | -1.3642 | |
| 225 | F | A | 0.0000 | mutated: LF225A |
| 226 | G | A | 0.0000 | |
| 227 | L | A | -0.8010 | |
| 228 | G | A | 0.0000 | |
| 229 | F | A | 0.0000 | |
| 230 | E | A | -1.4567 | |
| 231 | K | A | -1.7633 | |
| 232 | I | A | 0.0000 | mutated: VI232A |
| 233 | A | A | 0.0000 | mutated: SA233A |
| 234 | A | A | -1.4539 | |
| 235 | K | A | -1.4706 | |
| 236 | L | A | 0.0000 | |
| 237 | N | A | -1.5989 | |
| 238 | V | A | -1.3611 | |
| 239 | D | A | -2.1315 | |
| 240 | F | A | -1.9749 | |
| 241 | D | A | -3.1430 | |
| 242 | A | A | 0.0000 | |
| 243 | I | A | 0.0000 | |
| 244 | H | A | -3.0756 | |
| 245 | K | A | -3.5199 | |
| 246 | R | A | -2.8737 | |
| 247 | E | A | -3.4056 | |
| 248 | R | A | -2.5942 | |
| 249 | Q | A | -1.6894 | |
| 250 | V | A | 0.0000 | |
| 251 | A | A | 0.0000 | |
| 252 | I | A | 0.0000 | |
| 253 | A | A | 0.0000 | |
| 254 | S | A | 0.0000 | |
| 255 | F | A | 0.0000 | |
| 256 | K | A | 0.0933 | |
| 257 | Q | A | 0.0000 | |
| 258 | I | A | 0.0860 | |
| 259 | Y | A | 0.0000 | |
| 260 | Y | A | -0.6062 | |
| 261 | T | A | -0.4924 | |
| 262 | A | A | 0.0000 | |
| 263 | S | A | -0.9044 | |
| 264 | V | A | 0.0000 | |
| 265 | D | A | -1.9653 | |
| 266 | T | A | -1.0620 | |
| 267 | P | A | 0.0000 | |
| 268 | T | A | -0.6068 | |
| 269 | S | A | -0.8548 | |
| 270 | P | A | 0.0000 | |
| 271 | H | A | -1.0985 | |
| 272 | S | A | -0.4406 | |
| 273 | V | A | 0.0000 | |
| 274 | F | A | 0.0000 | |
| 275 | G | A | -0.8194 | |
| 276 | P | A | -0.9438 | |
| 277 | N | A | -1.4073 | |
| 278 | V | A | -0.9589 | |
| 279 | T | A | -1.2381 | |
| 280 | A | A | -1.7435 | |
| 281 | Q | A | -2.6608 | |
| 282 | D | A | -2.5384 | |
| 283 | L | A | 0.0000 | |
| 284 | K | A | -3.4955 | |
| 285 | D | A | -3.5348 | |
| 286 | R | A | -2.6253 | |
| 287 | G | A | -2.2964 | |
| 288 | V | A | 0.0000 | |
| 289 | N | A | -2.4206 | |
| 290 | N | A | -2.5949 | |
| 291 | K | A | -2.7258 | |
| 292 | N | A | -1.6700 | |
| 293 | P | A | 0.0000 | |
| 294 | L | A | 0.0000 | |
| 295 | G | A | 0.0000 | |
| 296 | Y | A | 0.0000 | |
| 297 | I | A | 0.0000 | |
| 298 | S | A | -0.2937 | |
| 299 | S | A | -0.5108 | |
| 300 | V | A | 0.0000 | |
| 301 | S | A | -0.3169 | |
| 302 | Y | A | 0.0000 | |
| 303 | G | A | 0.0000 | |
| 304 | R | A | 0.0000 | |
| 305 | Q | A | 0.0000 | |
| 306 | I | A | 0.0000 | |
| 307 | F | A | 0.0000 | |
| 308 | V | A | 0.0000 | |
| 309 | K | A | 0.0000 | |
| 310 | L | A | 0.0000 | |
| 311 | E | A | -1.2621 | |
| 312 | T | A | 0.0000 | |
| 313 | T | A | -1.4086 | |
| 314 | F | A | -1.2658 | mutated: SF314A |
| 315 | T | A | -0.8271 | |
| 316 | S | A | -1.3685 | |
| 317 | N | A | -1.9636 | |
| 318 | D | A | -2.2185 | |
| 319 | V | A | 0.0000 | |
| 320 | Q | A | -1.7870 | |
| 321 | A | A | -1.1141 | |
| 322 | A | A | 0.0000 | |
| 323 | F | A | 0.0000 | |
| 324 | S | A | -1.0673 | |
| 325 | G | A | -0.9301 | |
| 326 | L | A | 0.0000 | |
| 327 | F | A | 0.0000 | |
| 328 | K | A | -2.1172 | |
| 329 | A | A | -1.6803 | |
| 330 | K | A | -2.2834 | |
| 331 | F | A | 0.0000 | |
| 332 | G | A | -1.9872 | |
| 333 | N | A | -1.4096 | |
| 334 | L | A | -1.2415 | |
| 335 | S | A | -1.1362 | |
| 336 | T | A | -1.6111 | |
| 337 | E | A | -2.4961 | |
| 338 | F | A | -1.6833 | |
| 339 | K | A | -2.2330 | |
| 340 | A | A | -2.0132 | |
| 341 | K | A | -2.7149 | |
| 342 | Y | A | 0.0000 | |
| 343 | A | A | -2.0566 | |
| 344 | D | A | -2.2874 | |
| 345 | I | A | 0.0000 | |
| 346 | L | A | 0.0000 | |
| 347 | N | A | -2.8293 | |
| 348 | K | A | -2.7756 | |
| 349 | T | A | 0.0000 | |
| 350 | R | A | -2.8273 | |
| 351 | A | A | 0.0000 | |
| 352 | T | A | 0.0000 | |
| 353 | V | A | 0.0000 | |
| 354 | Y | A | 0.0000 | |
| 355 | A | A | 0.0000 | |
| 356 | V | A | 0.0000 | |
| 357 | S | A | 0.0000 | mutated: GS357A |
| 358 | G | A | 0.0000 | |
| 359 | S | A | 0.0000 | |
| 360 | A | A | -1.2962 | |
| 361 | R | A | -1.6302 | |
| 362 | G | A | -1.1782 | |
| 363 | G | A | -0.6739 | |
| 364 | V | A | 0.4840 | |
| 365 | E | A | -0.1394 | |
| 366 | V | A | 0.5145 | |
| 367 | A | A | 0.2636 | |
| 368 | T | A | -0.5679 | |
| 369 | G | A | -1.5418 | |
| 370 | N | A | -2.8183 | |
| 371 | I | A | -2.3084 | |
| 372 | D | A | -2.5727 | |
| 373 | A | A | -1.7696 | |
| 374 | L | A | 0.0000 | |
| 375 | K | A | -2.8101 | |
| 376 | K | A | -3.2455 | |
| 377 | I | A | -2.0818 | |
| 378 | I | A | 0.0000 | |
| 379 | K | A | -3.4447 | |
| 380 | E | A | -3.0933 | |
| 381 | E | A | 0.0000 | |
| 382 | S | A | -1.5550 | |
| 383 | T | A | -1.0260 | |
| 384 | Y | A | -0.5795 | |
| 385 | S | A | -0.8523 | |
| 386 | T | A | -1.0614 | |
| 387 | K | A | -1.6687 | |
| 388 | V | A | -0.9162 | |
| 389 | P | A | -0.6485 | |
| 390 | A | A | -0.0870 | |
| 391 | V | A | -0.1868 | |
| 392 | P | A | 0.0000 | |
| 393 | V | A | 0.0000 | |
| 394 | S | A | 0.0000 | |
| 395 | Y | A | 0.0000 | |
| 396 | A | A | -0.5172 | |
| 397 | V | A | 0.0000 | |
| 398 | N | A | -0.3668 | |
| 399 | F | A | 0.0000 | |
| 400 | L | A | 0.0000 | |
| 401 | K | A | -1.8123 | |
| 402 | D | A | -1.9415 | |
| 403 | N | A | -1.2452 | |
| 404 | Q | A | -1.0657 | |
| 405 | L | A | 0.1798 | |
| 406 | A | A | 0.0000 | |
| 407 | A | A | -0.3371 | |
| 408 | V | A | 0.0000 | |
| 409 | R | A | -1.2364 | |
| 410 | S | A | 0.0000 | |
| 411 | S | A | -1.5560 | |
| 412 | G | A | -1.5412 | |
| 413 | D | A | 0.0000 | |
| 414 | Y | A | 0.0000 | |
| 415 | I | A | -1.1980 | |
| 416 | E | A | -1.5122 | |
| 417 | T | A | -1.3622 | |
| 418 | T | A | -0.9939 | |
| 419 | A | A | -0.7558 | |
| 420 | T | A | -0.5734 | |
| 421 | T | A | -0.4432 | |
| 422 | Y | A | -0.3680 | |
| 423 | K | A | -1.6775 | |
| 424 | S | A | -1.2861 | |
| 425 | G | A | 0.0000 | |
| 426 | E | A | -1.0151 | |
| 427 | I | A | 0.0000 | |
| 428 | T | A | -1.3309 | |
| 429 | F | A | 0.0000 | |
| 430 | R | A | -1.6393 | |
| 431 | H | A | 0.0000 | |
| 432 | G | A | -0.2774 | |
| 433 | G | A | 0.0000 | |
| 434 | G | A | -0.3960 | |
| 435 | Y | A | 0.0000 | |
| 436 | V | A | 0.9306 | |
| 437 | A | A | 0.0000 | |
| 438 | K | A | 0.0003 | |
| 439 | F | A | 0.0000 | |
| 440 | R | A | -1.0337 | |
| 441 | L | A | 0.0000 | |
| 442 | K | A | -1.7138 | |
| 443 | W | A | 0.0000 | |
| 444 | D | A | -1.6118 | |
| 445 | E | A | -1.3198 | |
| 446 | I | A | 0.0000 | |
| 447 | S | A | -1.2645 | |
| 448 | Y | A | -1.9969 | |
| 449 | D | A | -1.7608 | |
| 450 | P | A | -1.6665 | |
| 451 | Q | A | -2.3579 | |
| 452 | G | A | -2.4974 | |
| 453 | K | A | -3.1384 | |
| 454 | E | A | -2.9254 | |
| 455 | I | A | -1.1650 | |
| 456 | R | A | -2.3261 | |
| 457 | T | A | -1.4244 | |
| 458 | P | A | -1.4833 | |
| 459 | K | A | -1.7019 | |
| 460 | T | A | -1.1458 | |
| 461 | W | A | 0.0000 | |
| 462 | S | A | -0.5079 | |
| 463 | G | A | -0.3755 | |
| 464 | N | A | -0.4685 | |
| 465 | W | A | 0.1171 | |
| 466 | A | A | 0.0494 | |
| 467 | A | A | 0.1454 | |
| 468 | R | A | -0.0785 | |
| 469 | T | A | 0.4148 | |
| 470 | L | A | 1.0146 | |
| 471 | G | A | -0.1653 | |
| 472 | F | A | -0.8021 | |
| 473 | R | A | -2.2920 | |
| 474 | E | A | -1.7773 | |
| 475 | T | A | -1.2740 | |
| 476 | I | A | 0.0000 | |
| 477 | Q | A | -1.5237 | |
| 478 | L | A | 0.0000 | |
| 479 | P | A | -0.7858 | |
| 480 | A | A | 0.0000 | |
| 481 | N | A | -0.7634 | |
| 482 | A | A | 0.0000 | |
| 483 | R | A | -1.2933 | |
| 484 | N | A | -1.8445 | |
| 485 | I | A | 0.0000 | |
| 486 | H | A | -2.1947 | |
| 487 | V | A | 0.0000 | |
| 488 | E | A | -1.5194 | |
| 489 | A | A | 0.0000 | |
| 490 | G | A | 0.0000 | |
| 491 | E | A | 0.0000 | |
| 492 | A | A | 0.3801 | |
| 493 | T | A | 0.0137 | |
| 494 | G | A | -0.0142 | |
| 495 | L | A | 0.4354 | |
| 496 | A | A | 0.3420 | |
| 497 | W | A | 0.5430 | |
| 498 | D | A | -0.7846 | |
| 499 | P | A | -0.1262 | |
| 500 | W | A | 0.6932 | |
| 501 | W | A | 0.8286 | |
| 502 | T | A | 0.2870 | |
| 503 | V | A | 0.3462 | |
| 504 | I | A | 0.0000 | |
| 505 | N | A | -2.1830 | |
| 506 | K | A | -2.5455 | |
| 507 | K | A | -3.2056 | |
| 508 | N | A | -2.4514 | |
| 509 | L | A | -1.3529 | |
| 510 | P | A | -0.6730 | |
| 511 | L | A | -0.3832 | |
| 512 | V | A | -0.2395 | |
| 513 | P | A | -0.9427 | |
| 514 | H | A | -0.8034 | |
| 515 | R | A | 0.0000 | |
| 516 | E | A | -1.2349 | |
| 517 | I | A | 0.0000 | |
| 518 | V | A | 0.0000 | |
| 519 | L | A | 0.0000 | |
| 520 | K | A | -0.4695 | |
| 521 | G | A | -0.7904 | |
| 522 | T | A | -1.0398 | |
| 523 | T | A | -0.9848 | |
| 524 | N | A | -1.9092 | mutated: LN524A |
| 525 | N | A | -1.8428 | |
| 526 | P | A | -0.5373 | |
| 527 | W | A | 0.3623 | |
| 528 | V | A | 0.0772 | |
| 529 | E | A | -1.0843 | |
| 530 | D | A | -1.1120 | |
| 531 | N | A | -1.0937 | |
| 532 | V | A | -0.0748 | |
| 533 | K | A | -1.2146 | |
| 534 | S | A | -0.6459 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine