Project name: a26a4ed567a67e

Chain sequence(s)	A: APVPVTKLVCDGDTYKCTAYLDYGDGKWVAQWDTAVFHTT; C: APVPVTKLVCDGDTYKCTAYLDYGDGKWVAQWDTAVFHTT; B: APVPVTKLVCDGDTYKCTAYLDYGDGKWVAQWDTAVFHTT
Selected Chain(s)	A,C,B
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:07)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:08)

• Minimal score value: -2.5598
• Maximal score value: 0.5675
• Average score: -0.7041
• Total score value: -84.4942

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.2663
2	P	A	-0.5212
3	V	A	-0.1044
4	P	A	-0.6980
5	V	A	-0.5958
6	T	A	-1.0137
7	K	A	-1.5636
8	L	A	-0.3037
9	V	A	-0.3872
10	C	A	0.0000
11	D	A	-0.8958
12	G	A	-0.7383
13	D	A	-1.8425
14	T	A	-1.1730
15	Y	A	-0.6498
16	K	A	-1.6054
17	C	A	0.0000
18	T	A	-0.4515
19	A	A	0.0000
20	Y	A	-0.3432
21	L	A	0.0000
22	D	A	-1.9075
23	Y	A	-0.3385
24	G	A	-1.3295
25	D	A	-2.4041
26	G	A	-1.8453
27	K	A	-1.6818
28	W	A	-0.5161
29	V	A	0.0000
30	A	A	0.0000
31	Q	A	-0.5117
32	W	A	-1.2234
33	D	A	-1.8574
34	T	A	0.0000
35	A	A	-0.1778
36	V	A	0.1339
37	F	A	0.5675
38	H	A	-0.6552
39	T	A	-0.5147
40	T	A	-0.4566
1	A	B	-0.2876
2	P	B	-0.5689
3	V	B	-0.1703
4	P	B	-0.6643
5	V	B	-0.5672
6	T	B	-1.0348
7	K	B	-1.5711
8	L	B	-0.3285
9	V	B	-0.4312
10	C	B	0.0000
11	D	B	-0.9597
12	G	B	-0.8071
13	D	B	-1.8825
14	T	B	-1.2394
15	Y	B	-0.7882
16	K	B	-1.6634
17	C	B	0.0000
18	T	B	-0.4779
19	A	B	0.0000
20	Y	B	-0.4626
21	L	B	0.0000
22	D	B	-2.0196
23	Y	B	-0.4354
24	G	B	-1.4313
25	D	B	-2.5598
26	G	B	-2.1135
27	K	B	-2.2500
28	W	B	-0.8461
29	V	B	0.0000
30	A	B	0.0000
31	Q	B	-0.5181
32	W	B	-1.2396
33	D	B	-1.8973
34	T	B	0.0000
35	A	B	-0.2150
36	V	B	0.0970
37	F	B	0.5307
38	H	B	-0.6889
39	T	B	-0.5329
40	T	B	-0.4660
1	A	C	-0.2461
2	P	C	-0.4806
3	V	C	-0.0253
4	P	C	-0.5781
5	V	C	-0.3854
6	T	C	-0.7229
7	K	C	-1.0371
8	L	C	-0.1514
9	V	C	0.0000
10	C	C	0.0000
11	D	C	-0.9057
12	G	C	-0.7274
13	D	C	-1.8124
14	T	C	-1.1175
15	Y	C	-0.5681
16	K	C	-1.4969
17	C	C	0.0000
18	T	C	-0.4246
19	A	C	0.0000
20	Y	C	-0.1775
21	L	C	0.0000
22	D	C	-1.8164
23	Y	C	-0.3213
24	G	C	-1.3250
25	D	C	-2.4103
26	G	C	-1.8571
27	K	C	-1.6720
28	W	C	-0.4951
29	V	C	0.0000
30	A	C	0.0000
31	Q	C	-0.4853
32	W	C	-1.1800
33	D	C	-1.7968
34	T	C	0.0000
35	A	C	-0.1697
36	V	C	0.0940
37	F	C	0.3729
38	H	C	-0.9045
39	T	C	-0.7279
40	T	C	-0.5806