Project name: design-26-s06

Chain sequence(s)	H: QVQLVESGGGLVQPGGSLRLSCAASGASRPISSYSWAWFRQAPGQGLEAVAAIGGDGSYSVYHPAVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAAGGGGPSDGKEYWGQGTLVTVS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:43)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:44)

• Minimal score value: -2.7568
• Maximal score value: 1.6993
• Average score: -0.6283
• Total score value: -76.0201

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5861
2	V	H	-1.3019
3	Q	H	-1.2494
4	L	H	0.0000
5	V	H	0.9110
6	E	H	0.0000
7	S	H	-0.1865
8	G	H	-0.5054
9	G	H	0.2047
10	G	H	0.8771
11	L	H	1.3862
12	V	H	-0.0590
13	Q	H	-1.3563
14	P	H	-1.6753
15	G	H	-1.4641
16	G	H	-0.9688
17	S	H	-1.1046
18	L	H	-0.6831
19	R	H	-1.6918
20	L	H	0.0000
21	S	H	-0.2961
22	C	H	0.0000
23	A	H	-0.2037
24	A	H	0.0000
25	S	H	-0.7465
26	G	H	-1.3633
27	A	H	-1.3407
28	S	H	-1.2574
29	R	H	-1.6658
30	P	H	-1.1405
31	I	H	-1.1467
32	S	H	-1.3572
33	S	H	-0.9691
34	Y	H	0.0000
35	S	H	-0.6294
36	W	H	0.0000
37	A	H	0.0000
38	W	H	0.0000
39	F	H	0.0000
40	R	H	0.0000
41	Q	H	-0.4398
42	A	H	-0.8494
43	P	H	-0.9915
44	G	H	-1.2220
45	Q	H	-1.6516
46	G	H	-0.8286
47	L	H	0.3831
48	E	H	-0.3668
49	A	H	-0.0761
50	V	H	0.0000
51	A	H	0.0000
52	A	H	0.4233
53	I	H	0.0000
54	G	H	-0.3958
55	G	H	-1.1687
56	D	H	-1.9864
57	G	H	-1.1335
58	S	H	-0.3061
59	Y	H	0.9972
60	S	H	1.0325
61	V	H	1.1023
62	Y	H	-0.0188
63	H	H	-0.5988
64	P	H	-0.8173
65	A	H	-0.8724
66	V	H	0.0000
67	K	H	-1.8510
68	G	H	-1.4277
69	R	H	0.0000
70	F	H	0.0000
71	T	H	-0.5929
72	I	H	0.0000
73	S	H	-0.3756
74	R	H	-1.4472
75	D	H	-1.8863
76	N	H	-2.4224
77	S	H	-1.8359
78	K	H	-2.5576
79	N	H	-1.9394
80	T	H	-1.1346
81	L	H	0.0000
82	Y	H	-0.5396
83	L	H	0.0000
84	Q	H	-0.9722
85	M	H	0.0000
86	N	H	-1.2683
87	S	H	-1.2193
88	L	H	0.0000
89	R	H	-2.3685
90	A	H	-1.7814
91	E	H	-2.2524
92	D	H	0.0000
93	T	H	-0.4332
94	A	H	0.0000
95	V	H	0.8315
96	Y	H	0.0000
97	Y	H	0.4390
98	C	H	0.0000
99	A	H	0.0000
100	A	H	0.0000
101	G	H	-1.0537
102	G	H	-1.4787
103	G	H	-1.1390
104	G	H	-1.3397
105	P	H	-1.3429
106	S	H	-1.6807
107	D	H	-2.7568
108	G	H	-2.4462
109	K	H	-2.5188
110	E	H	-1.4908
111	Y	H	-0.4740
112	W	H	0.0738
113	G	H	-0.0755
114	Q	H	-0.8560
115	G	H	0.0812
116	T	H	0.6011
117	L	H	1.6993
118	V	H	0.0000
119	T	H	0.3433
120	V	H	0.0000
121	S	H	-0.7761