Project name: 5WUV

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGYVFTDYGMNWVRQAPGKGLEWMGWINTYIGEPIYADSVKGRFTFSLDTSKSTAYLQMNSLRAEDTAVYYCARGYRSYAMDYWGQGTLVTVSS; L: DIQMTQSPSSLSASVGDRVTITCKASQNVGTNVAWYQQKPGKAPKALIYSASFLYSGVPYRFSGSGSGTDFTLTISSLQPEDFATYYCQQYNIYPLTFGQGTKVEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:57)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:59)

• Minimal score value: -2.6678
• Maximal score value: 2.1168
• Average score: -0.4741
• Total score value: -106.6635

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.1768
2	V	H	-1.1338
3	Q	H	-1.3098
4	L	H	0.0000
5	V	H	1.1230
6	E	H	0.0000
7	S	H	-0.1995
8	G	H	-0.5722
9	G	H	0.1179
11	G	H	0.8099
12	L	H	1.3608
13	V	H	-0.0604
14	Q	H	-1.3302
15	P	H	-1.5992
16	G	H	-1.3535
17	G	H	-1.1444
18	S	H	-1.1971
19	L	H	-0.9364
20	R	H	-1.9767
21	L	H	0.0000
22	S	H	-0.2230
23	C	H	0.0000
24	A	H	0.0832
25	A	H	0.0000
26	S	H	-0.6421
27	G	H	-0.9391
28	Y	H	0.0926
29	V	H	1.2687
30	F	H	0.0000
35	T	H	0.4806
36	D	H	-0.7399
37	Y	H	-0.1120
38	G	H	-0.1306
39	M	H	0.0000
40	N	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	0.0000
44	Q	H	-0.6259
45	A	H	-1.0082
46	P	H	-0.8198
47	G	H	-1.4784
48	K	H	-2.3449
49	G	H	-1.5831
50	L	H	0.0000
51	E	H	-0.9813
52	W	H	0.0000
53	M	H	0.0000
54	G	H	0.0000
55	W	H	0.1018
56	I	H	0.0000
57	N	H	0.2433
58	T	H	0.0000
59	Y	H	1.6620
62	I	H	2.1168
63	G	H	0.5207
64	E	H	-0.3677
65	P	H	-0.1919
66	I	H	-0.1124
67	Y	H	-0.5741
68	A	H	0.0000
69	D	H	-2.6559
70	S	H	-1.6885
71	V	H	0.0000
72	K	H	-2.6678
74	G	H	-1.8334
75	R	H	-1.6163
76	F	H	0.0000
77	T	H	-0.7921
78	F	H	0.0000
79	S	H	-0.1657
80	L	H	-0.0740
81	D	H	-0.8346
82	T	H	-0.4864
83	S	H	-1.1454
84	K	H	-1.9370
85	S	H	-0.7507
86	T	H	0.0000
87	A	H	0.0000
88	Y	H	-0.1685
89	L	H	0.0000
90	Q	H	-1.0938
91	M	H	0.0000
92	N	H	-1.3096
93	S	H	-1.1966
94	L	H	0.0000
95	R	H	-2.3692
96	A	H	-1.7254
97	E	H	-2.2538
98	D	H	0.0000
99	T	H	-0.3833
100	A	H	0.0000
101	V	H	0.7060
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	A	H	0.0000
106	R	H	0.0000
107	G	H	-0.1263
108	Y	H	-0.2983
109	R	H	-1.4770
110	S	H	-0.7682
113	Y	H	-0.2616
114	A	H	0.0000
115	M	H	0.0000
116	D	H	-0.0505
117	Y	H	0.0716
118	W	H	-0.2541
119	G	H	0.0000
120	Q	H	-1.2603
121	G	H	-0.3101
122	T	H	0.0000
123	L	H	1.6540
124	V	H	0.0000
125	T	H	0.3295
126	V	H	0.0000
127	S	H	-0.5509
128	S	H	-0.5606
1	D	L	-2.0837
2	I	L	0.0000
3	Q	L	-2.2561
4	M	L	0.0000
5	T	L	-1.3555
6	Q	L	0.0000
7	S	L	-0.6575
8	P	L	-0.6053
9	S	L	-1.0079
10	S	L	-1.1836
11	L	L	-0.8677
12	S	L	-0.9453
13	A	L	-0.9251
14	S	L	-0.8427
15	V	L	-0.0946
16	G	L	-0.7055
17	D	L	-1.8019
18	R	L	-2.2771
19	V	L	0.0000
20	T	L	-0.6353
21	I	L	0.0000
22	T	L	-0.8242
23	C	L	0.0000
24	K	L	-2.6181
25	A	L	0.0000
26	S	L	-2.1430
27	Q	L	-2.6436
28	N	L	-2.3968
29	V	L	0.0000
36	G	L	-1.3641
37	T	L	-0.7523
38	N	L	-0.6895
39	V	L	0.0000
40	A	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	0.0000
45	K	L	-1.5934
46	P	L	-1.1562
47	G	L	-1.6455
48	K	L	-2.5588
49	A	L	-1.5258
50	P	L	0.0000
51	K	L	-1.1646
52	A	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	0.7745
56	S	L	0.2113
57	A	L	0.0000
65	S	L	0.7201
66	F	L	2.1030
67	L	L	1.5065
68	Y	L	0.7316
69	S	L	-0.0392
70	G	L	-0.3083
71	V	L	0.0000
72	P	L	0.3616
74	Y	L	1.1074
75	R	L	-0.0263
76	F	L	0.0000
77	S	L	0.3232
78	G	L	0.1668
79	S	L	-0.4385
80	G	L	-1.1454
83	S	L	-1.3778
84	G	L	-1.7516
85	T	L	-2.1702
86	D	L	-2.6210
87	F	L	0.0000
88	T	L	-0.7790
89	L	L	0.0000
90	T	L	-0.6124
91	I	L	0.0000
92	S	L	-1.0936
93	S	L	-1.0262
94	L	L	0.0000
95	Q	L	-0.7170
96	P	L	-0.9668
97	E	L	-1.6596
98	D	L	0.0000
99	F	L	-0.1773
100	A	L	0.0000
101	T	L	-0.9808
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	Q	L	0.0000
107	Y	L	0.0000
108	N	L	-0.3749
109	I	L	0.5401
114	Y	L	0.6159
115	P	L	-0.1807
116	L	L	0.0000
117	T	L	-0.6372
118	F	L	0.0000
119	G	L	0.0000
120	Q	L	-1.7550
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-2.0104
124	V	L	0.0000
125	E	L	-1.2513
126	I	L	-0.6556
127	K	L	-1.5608