Project name: a6ed84db65a378f

Chain sequence(s)	H: EGQLLESGGALVQPGGSLRLSCAASGFTFTSYAMSWVRQAPGKGLQWVAGINGGGDTTHYADSVKGRFTISRDNSKNTLSLQWNSLRAEDTAMYYCAKPAPLEYGDTSSYYYYGMDVWGQGTTVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:18)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:19)

• Minimal score value: -2.8764
• Maximal score value: 3.3126
• Average score: -0.6661
• Total score value: -85.2554

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.2909
2	G	H	-1.6205
3	Q	H	-1.4706
4	L	H	0.0000
5	L	H	0.9626
6	E	H	0.0000
7	S	H	-0.4933
8	G	H	-0.9306
9	G	H	-0.3540
10	A	H	0.4240
11	L	H	1.1732
12	V	H	0.0000
13	Q	H	-1.4979
14	P	H	-1.8681
15	G	H	-1.6455
16	G	H	-1.1977
17	S	H	-1.6242
18	L	H	-1.0889
19	R	H	-2.3004
20	L	H	0.0000
21	S	H	-0.5511
22	C	H	0.0000
23	A	H	-0.2565
24	A	H	0.0000
25	S	H	-1.1799
26	G	H	-1.3967
27	F	H	-0.6073
28	T	H	-0.2783
29	F	H	0.0000
30	T	H	-0.8403
31	S	H	-0.4939
32	Y	H	-0.4378
33	A	H	-0.4531
34	M	H	0.0000
35	S	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	-0.5242
39	Q	H	-1.0980
40	A	H	-1.4440
41	P	H	-1.1977
42	G	H	-1.5232
43	K	H	-2.3345
44	G	H	-1.3680
45	L	H	-0.3275
46	Q	H	-0.6721
47	W	H	0.1946
48	V	H	0.0000
49	A	H	0.0000
50	G	H	-0.5996
51	I	H	0.0000
52	N	H	-2.1262
53	G	H	0.0000
54	G	H	-1.7376
55	G	H	-1.9858
56	D	H	-2.4118
57	T	H	-1.7117
58	T	H	-1.2304
59	H	H	-1.4459
60	Y	H	-1.1694
61	A	H	-1.4594
62	D	H	-2.6454
63	S	H	-1.7967
64	V	H	0.0000
65	K	H	-2.8368
66	G	H	-1.9883
67	R	H	-2.0269
68	F	H	0.0000
69	T	H	-1.1761
70	I	H	0.0000
71	S	H	-0.9159
72	R	H	-1.5661
73	D	H	-1.7758
74	N	H	-1.9403
75	S	H	-1.7077
76	K	H	-2.5147
77	N	H	-1.9835
78	T	H	-1.1798
79	L	H	0.0000
80	S	H	-0.8376
81	L	H	0.0000
82	Q	H	-1.5466
83	W	H	0.0000
84	N	H	-2.2646
85	S	H	-1.6956
86	L	H	0.0000
87	R	H	-2.8764
88	A	H	-1.9891
89	E	H	-2.4277
90	D	H	0.0000
91	T	H	-0.8470
92	A	H	0.0000
93	M	H	-0.0856
94	Y	H	0.0000
95	Y	H	0.1292
96	C	H	0.0000
97	A	H	0.0000
98	K	H	0.0000
99	P	H	0.0000
100	A	H	-0.2265
101	P	H	-0.5835
102	L	H	0.4691
103	E	H	-1.3522
104	Y	H	-0.0708
105	G	H	-1.0026
106	D	H	-1.4265
107	T	H	-0.5575
108	S	H	0.1747
109	S	H	1.1775
110	Y	H	2.7155
111	Y	H	2.7687
112	Y	H	3.3126
113	Y	H	2.4655
114	G	H	0.6454
115	M	H	-0.0633
116	D	H	-1.4031
117	V	H	-0.6087
118	W	H	-0.0960
119	G	H	-0.0830
120	Q	H	-0.8572
121	G	H	0.0000
122	T	H	-0.1740
123	T	H	-0.0445
124	V	H	0.0000
125	T	H	-0.0763
126	V	H	0.0000
127	S	H	-0.8449
128	S	H	-0.5287