Project name: a86d3dd24e2a54d

Chain sequence(s)	D: EVQLVESGGGLVQPGGSLRLSCAASGFTIGTDVTSMGWFRQAPGKGRELVAYITSSSTYYADSVKGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAAGVAGIFDYWGQGTQVTVSS
Selected Chain(s)	D
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with D chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:57)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:58)

• Minimal score value: -2.9644
• Maximal score value: 1.8149
• Average score: -0.654
• Total score value: -76.5196

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	D	-2.2056
2	V	D	-1.6888
3	Q	D	-1.3025
4	L	D	0.0000
5	V	D	1.2040
6	E	D	0.0000
7	S	D	-0.5222
8	G	D	-1.0326
9	G	D	-0.7699
10	G	D	-0.0496
11	L	D	0.9841
12	V	D	-0.1354
13	Q	D	-1.4787
14	P	D	-1.8749
15	G	D	-1.6143
16	G	D	-1.1033
17	S	D	-1.3914
18	L	D	-0.9387
19	R	D	-2.1352
20	L	D	0.0000
21	S	D	-0.3209
22	C	D	0.0000
23	A	D	-0.1706
24	A	D	0.0000
25	S	D	-1.2140
26	G	D	-1.6607
27	F	D	0.0000
28	T	D	-0.9474
29	I	D	0.0000
30	G	D	-0.8022
31	T	D	-0.7695
32	D	D	-1.2714
33	V	D	0.0000
34	T	D	-0.3087
35	S	D	0.0000
36	M	D	0.0000
37	G	D	0.0000
38	W	D	0.0000
39	F	D	-0.1223
40	R	D	0.0000
41	Q	D	-1.7286
42	A	D	-1.7602
43	P	D	-1.3028
44	G	D	-1.5313
45	K	D	-2.5744
46	G	D	-2.0478
47	R	D	-1.9612
48	E	D	-1.2488
49	L	D	0.0871
50	V	D	0.0000
51	A	D	0.0000
52	Y	D	0.6489
53	I	D	0.0000
54	T	D	-0.1064
55	S	D	-0.5824
56	S	D	-0.4398
57	S	D	-0.0786
58	T	D	0.4332
59	Y	D	0.8815
60	Y	D	-0.2402
61	A	D	-1.0009
62	D	D	-2.3967
63	S	D	-1.8218
64	V	D	0.0000
65	K	D	-2.4922
66	G	D	-1.8067
67	R	D	-1.6373
68	F	D	0.0000
69	T	D	-0.7213
70	I	D	0.0000
71	S	D	-0.3750
72	R	D	-1.0893
73	D	D	-1.6390
74	N	D	-1.9509
75	A	D	-1.5799
76	K	D	-2.5342
77	R	D	-2.3314
78	M	D	-1.1126
79	V	D	0.0000
80	Y	D	-0.5364
81	L	D	0.0000
82	Q	D	-1.2863
83	M	D	0.0000
84	N	D	-1.6802
85	S	D	-1.5077
86	L	D	0.0000
87	R	D	-2.9644
88	A	D	-2.0438
89	E	D	-2.4967
90	D	D	0.0000
91	T	D	-0.9882
92	A	D	0.0000
93	V	D	-0.5367
94	Y	D	0.0000
95	Y	D	-0.1528
96	C	D	0.0000
97	A	D	0.0000
98	A	D	0.0000
99	G	D	0.0000
100	V	D	0.9744
101	A	D	0.9518
102	G	D	0.7689
103	I	D	1.8149
104	F	D	0.6637
105	D	D	-0.7349
106	Y	D	-0.1001
107	W	D	0.0249
108	G	D	-0.0205
109	Q	D	-0.9543
110	G	D	-0.4343
111	T	D	-0.6530
112	Q	D	-1.1002
113	V	D	0.0000
114	T	D	-0.3800
115	V	D	0.0000
116	S	D	-0.8947
117	S	D	-0.5693