Project name: a87ea3c4001f1c7

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGFTFSSYAMAWFRQAPGKGRELVAAISSSGGYTYYADSVKGRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAARSGGLTKESAFDESKYDYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:57)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:58)

• Minimal score value: -2.6688
• Maximal score value: 0.8994
• Average score: -0.7598
• Total score value: -96.4906

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.1290
2	V	A	-1.1540
3	Q	A	-1.3339
4	L	A	0.0000
5	V	A	0.8330
6	E	A	0.0000
7	S	A	-0.4523
8	G	A	-0.9612
9	G	A	-0.7410
10	G	A	0.0973
11	L	A	0.8994
12	V	A	0.0000
13	Q	A	-1.3830
14	P	A	-1.5188
15	G	A	-1.3373
16	G	A	-0.9195
17	S	A	-1.3143
18	L	A	-1.0166
19	R	A	-2.2643
20	L	A	0.0000
21	S	A	-0.4465
22	C	A	0.0000
23	A	A	-0.1383
24	A	A	0.0000
25	S	A	-0.9032
26	G	A	-1.2794
27	F	A	-0.5628
28	T	A	-0.2677
29	F	A	0.0000
30	S	A	-0.6309
31	S	A	-0.4610
32	Y	A	-0.4891
33	A	A	0.0000
34	M	A	0.0000
35	A	A	0.0000
36	W	A	0.0000
37	F	A	0.0000
38	R	A	0.0000
39	Q	A	-1.6655
40	A	A	-1.6535
41	P	A	-1.1710
42	G	A	-1.6538
43	K	A	-2.6688
44	G	A	-2.1829
45	R	A	-2.1301
46	E	A	-2.0013
47	L	A	0.0000
48	V	A	0.0000
49	A	A	0.0000
50	A	A	0.0000
51	I	A	0.0000
52	S	A	0.0000
53	S	A	-0.4509
54	S	A	-0.4793
55	G	A	-0.3944
56	G	A	-0.0203
57	Y	A	0.7562
58	T	A	0.3359
59	Y	A	-0.3079
60	Y	A	-0.8032
61	A	A	0.0000
62	D	A	-2.3878
63	S	A	-1.7382
64	V	A	0.0000
65	K	A	-2.5514
66	G	A	-1.7343
67	R	A	-1.3795
68	F	A	0.0000
69	T	A	-0.9599
70	I	A	0.0000
71	S	A	-0.5410
72	R	A	-1.0466
73	D	A	-1.6363
74	N	A	-1.6474
75	A	A	-1.3750
76	K	A	-2.2701
77	R	A	-1.7553
78	M	A	-0.9057
79	V	A	0.0000
80	Y	A	-0.6859
81	L	A	0.0000
82	Q	A	-1.6527
83	M	A	0.0000
84	N	A	-1.3967
85	S	A	-1.0960
86	L	A	0.0000
87	R	A	-2.1108
88	A	A	-1.6761
89	E	A	-2.1835
90	D	A	0.0000
91	T	A	-0.8308
92	A	A	0.0000
93	V	A	-0.3048
94	Y	A	0.0000
95	Y	A	-0.2070
96	C	A	0.0000
97	A	A	0.0000
98	A	A	0.0000
99	R	A	-1.2887
100	S	A	-1.0379
101	G	A	-0.9435
102	G	A	-0.6375
103	L	A	0.0000
104	T	A	-1.2696
105	K	A	-2.1709
106	E	A	-2.3948
107	S	A	-1.8223
108	A	A	0.0000
109	F	A	-0.5815
110	D	A	-1.5611
111	E	A	-1.6953
112	S	A	-1.4869
113	K	A	-2.0843
114	Y	A	0.0000
115	D	A	-1.8942
116	Y	A	-0.6434
117	W	A	-0.2272
118	G	A	-0.1750
119	Q	A	-0.8895
120	G	A	0.0000
121	T	A	-0.6280
122	Q	A	-0.9149
123	V	A	0.0000
124	T	A	-0.3114
125	V	A	0.0000
126	S	A	-0.8174
127	S	A	-0.5773