Project name: a9260d97d5ec8ae

Chain sequence(s)	A: FEFEFEGSKGH; C: FEFEFEGSKGH; B: FEFEFEGSKGH; E: FEFEFEGSKGH; D: FEFEFEGSKGH; G: FEFEFEGSKGH; F: FEFEFEGSKGH; I: FEFEFEGSKGH; H: FEFEFEGSKGH; K: FEFEFEGSKGH; J: FEFEFEGSKGH; L: FEFEFEGSKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:06:19)
[INFO]       Main:     Simulation completed successfully.                                          (00:06:22)

• Minimal score value: -3.88
• Maximal score value: 1.1249
• Average score: -1.635
• Total score value: -215.8215

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	-1.4092
2	E	A	-2.6293
3	F	A	0.0000
4	E	A	-2.8030
5	F	A	0.0000
6	E	A	-3.3825
7	G	A	0.0000
8	S	A	-2.4906
9	K	A	0.0000
10	G	A	-1.9741
11	H	A	-1.3027
1	F	B	-1.3131
2	E	B	-2.8434
3	F	B	0.0000
4	E	B	-3.2283
5	F	B	0.0000
6	E	B	-3.8800
7	G	B	0.0000
8	S	B	-2.5595
9	K	B	0.0000
10	G	B	-1.6903
11	H	B	-1.1181
1	F	C	0.4372
2	E	C	-1.6962
3	F	C	-1.6170
4	E	C	-2.8980
5	F	C	-2.6051
6	E	C	-3.2204
7	G	C	-2.3644
8	S	C	-1.6178
9	K	C	-2.0842
10	G	C	-1.6452
11	H	C	-1.3209
1	F	D	0.5420
2	E	D	-1.8278
3	F	D	-1.1729
4	E	D	-2.4540
5	F	D	-1.0324
6	E	D	-2.5638
7	G	D	-2.5280
8	S	D	-2.1594
9	K	D	-2.6673
10	G	D	-2.1884
11	H	D	-2.1067
1	F	E	-0.8274
2	E	E	-2.7466
3	F	E	0.0000
4	E	E	-3.4025
5	F	E	0.0000
6	E	E	-3.6631
7	G	E	0.0000
8	S	E	-2.5249
9	K	E	-2.3454
10	G	E	-2.5197
11	H	E	-2.3035
1	F	F	-1.6680
2	E	F	-3.2170
3	F	F	0.0000
4	E	F	-3.1397
5	F	F	0.0000
6	E	F	-3.7519
7	G	F	0.0000
8	S	F	-2.5596
9	K	F	0.0000
10	G	F	-1.9701
11	H	F	-1.5687
1	F	G	-1.4941
2	E	G	-2.9104
3	F	G	0.0000
4	E	G	-2.8862
5	F	G	0.0000
6	E	G	-3.8417
7	G	G	0.0000
8	S	G	-2.6385
9	K	G	0.0000
10	G	G	-2.5528
11	H	G	-2.0522
1	F	H	-1.4109
2	E	H	-2.8109
3	F	H	0.0000
4	E	H	-2.9830
5	F	H	0.0000
6	E	H	-3.8037
7	G	H	0.0000
8	S	H	-2.7316
9	K	H	0.0000
10	G	H	-2.3230
11	H	H	-1.9415
1	F	I	-1.4431
2	E	I	-3.0450
3	F	I	0.0000
4	E	I	-3.4254
5	F	I	0.0000
6	E	I	-3.7744
7	G	I	0.0000
8	S	I	-2.3587
9	K	I	0.0000
10	G	I	-1.7488
11	H	I	-1.0861
1	F	J	0.4556
2	E	J	-1.6454
3	F	J	-1.3395
4	E	J	-2.3069
5	F	J	-1.3918
6	E	J	-2.7351
7	G	J	-2.4302
8	S	J	-1.9802
9	K	J	-2.0693
10	G	J	-1.8768
11	H	J	-1.5885
1	F	K	1.1249
2	E	K	-1.1426
3	F	K	-0.9350
4	E	K	-2.7426
5	F	K	-1.9258
6	E	K	-2.6502
7	G	K	-1.7955
8	S	K	-1.1026
9	K	K	-1.3019
10	G	K	-1.5635
11	H	K	-1.6190
1	F	L	-0.0714
2	E	L	-2.0371
3	F	L	0.0000
4	E	L	-3.0423
5	F	L	0.0000
6	E	L	-3.2535
7	G	L	-2.1443
8	S	L	-1.8533
9	K	L	0.0000
10	G	L	-1.9396
11	H	L	-2.0332