Project name: EEEEEEH6HAIGF2

Chain sequence(s)	A: AMEEEEEEQLQLVESGGGLVQPGGSLRLSCAASGFSLDPYVIGWFRQAPGKEREGVSCITSRAASRTSVDSVNERFTISRDNAKNTVDLHINNLKPEDSGVYYCAAVPPAKLPLFSLCRSLPAKYDYWGQGTQVTVSSAHHSEDPSGSYPYDVPDYAGSGASAYRPSRTLCGGELVDTLQLVCGDRGFYFSRPASRVSRRPRGIVEECCFRSCDLALLETYCATPAKSEAAALEHHHHHH
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:03)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:04)

• Minimal score value: -5.185
• Maximal score value: 2.8557
• Average score: -0.8812
• Total score value: -211.4989

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.2173
2	M	A	-0.6601
3	E	A	-3.0073
4	E	A	-4.1328
5	E	A	-4.8407
6	E	A	-5.1850
7	E	A	-4.7875
8	E	A	-4.2277
9	Q	A	-2.9380
10	L	A	0.0000
11	Q	A	-1.0911
12	L	A	0.0000
13	V	A	-0.1577
14	E	A	0.0000
15	S	A	0.0000
16	G	A	-1.6261
17	G	A	-0.7845
18	G	A	0.0624
19	L	A	0.8333
20	V	A	0.0000
21	Q	A	-1.6160
22	P	A	-1.7925
23	G	A	-1.8822
24	G	A	-1.4708
25	S	A	-1.6801
26	L	A	-1.2701
27	R	A	-2.1602
28	L	A	0.0000
29	S	A	0.0000
30	C	A	0.0000
31	A	A	0.0000
32	A	A	0.0000
33	S	A	0.0000
34	G	A	-0.8179
35	F	A	-0.2612
36	S	A	-0.5455
37	L	A	0.0000
38	D	A	-1.5622
39	P	A	-0.8118
40	Y	A	0.0000
41	V	A	0.0000
42	I	A	0.0000
43	G	A	0.0000
44	W	A	0.0000
45	F	A	0.0000
46	R	A	-1.4697
47	Q	A	-2.0314
48	A	A	-1.9680
49	P	A	-1.3675
50	G	A	-1.8929
51	K	A	-3.2894
52	E	A	-3.4698
53	R	A	-2.4588
54	E	A	-2.3110
55	G	A	-1.0973
56	V	A	0.0000
57	S	A	0.0000
58	C	A	0.0000
59	I	A	0.0000
60	T	A	-0.1943
61	S	A	-0.8342
62	R	A	-1.4320
63	A	A	-1.2339
64	A	A	-1.2540
65	S	A	-1.2278
66	R	A	-2.1786
67	T	A	-0.8225
68	S	A	0.0000
69	V	A	1.2273
70	D	A	0.3026
71	S	A	-0.0868
72	V	A	0.9300
73	N	A	-0.9464
74	E	A	-2.2223
75	R	A	-1.8241
76	F	A	0.0000
77	T	A	-0.5336
78	I	A	0.0000
79	S	A	0.0000
80	R	A	0.0000
81	D	A	-1.3759
82	N	A	-1.8918
83	A	A	-1.9351
84	K	A	-2.3096
85	N	A	-1.4986
86	T	A	0.0000
87	V	A	0.0000
88	D	A	-0.5750
89	L	A	0.0000
90	H	A	-1.4008
91	I	A	0.0000
92	N	A	-2.3343
93	N	A	-2.5341
94	L	A	0.0000
95	K	A	-2.4117
96	P	A	-1.8797
97	E	A	-2.2752
98	D	A	0.0000
99	S	A	-0.9902
100	G	A	-1.0431
101	V	A	-0.5088
102	Y	A	0.0000
103	Y	A	-0.4421
104	C	A	0.0000
105	A	A	0.0000
106	A	A	0.0000
107	V	A	0.0000
108	P	A	-0.7581
109	P	A	-0.6065
110	A	A	-0.8171
111	K	A	-1.7709
112	L	A	0.1690
113	P	A	1.0566
114	L	A	2.2136
115	F	A	2.8557
116	S	A	1.6173
117	L	A	2.1459
118	C	A	1.4395
119	R	A	0.1908
120	S	A	-0.1695
121	L	A	0.1008
122	P	A	-0.7362
123	A	A	-0.4598
124	K	A	-1.2808
125	Y	A	0.0000
126	D	A	-1.4942
127	Y	A	-0.5448
128	W	A	-0.1927
129	G	A	-0.4524
130	Q	A	-1.2384
131	G	A	-0.7879
132	T	A	0.0000
133	Q	A	-1.1612
134	V	A	0.0000
135	T	A	-0.4072
136	V	A	0.0000
137	S	A	-0.8794
138	S	A	-1.0502
139	A	A	-0.8926
140	H	A	-2.0347
141	H	A	-2.2919
142	S	A	-2.5287
143	E	A	-3.4286
144	D	A	-3.2219
145	P	A	-2.0027
146	S	A	-1.2499
147	G	A	-0.9995
148	S	A	0.0137
149	Y	A	1.0609
150	P	A	0.6233
151	Y	A	1.2694
152	D	A	-0.4768
153	V	A	0.9962
154	P	A	-0.0450
155	D	A	-1.0608
156	Y	A	0.5463
157	A	A	-0.2075
158	G	A	-0.4474
159	S	A	-0.4845
160	G	A	-0.6832
161	A	A	-0.1805
162	S	A	-0.2012
163	A	A	-0.1058
164	Y	A	0.3029
165	R	A	-1.6745
166	P	A	-1.5494
167	S	A	-2.0032
168	R	A	-2.6124
169	T	A	-1.2859
170	L	A	0.0000
171	C	A	-0.2786
172	G	A	-0.9806
173	G	A	-1.8632
174	E	A	-2.5241
175	L	A	0.0000
176	V	A	0.0000
177	D	A	-2.1081
178	T	A	-0.6472
179	L	A	0.0000
180	Q	A	-0.8904
181	L	A	0.7979
182	V	A	0.4053
183	C	A	0.0000
184	G	A	-0.9946
185	D	A	-2.4115
186	R	A	-1.9978
187	G	A	-1.2911
188	F	A	0.0000
189	Y	A	-0.1013
190	F	A	0.0000
191	S	A	-1.2371
192	R	A	-1.7909
193	P	A	-2.3547
194	A	A	-2.3468
195	S	A	-1.6859
196	R	A	-1.8122
197	V	A	0.0580
198	S	A	-1.5776
199	R	A	-3.0627
200	R	A	-3.3651
201	P	A	-2.5454
202	R	A	-2.5487
203	G	A	-1.0952
204	I	A	0.0000
205	V	A	0.6197
206	E	A	0.0286
207	E	A	0.0000
208	C	A	0.0000
209	C	A	0.3045
210	F	A	1.0455
211	R	A	-1.2448
212	S	A	-1.5852
213	C	A	0.0000
214	D	A	-1.5713
215	L	A	0.6358
216	A	A	0.1443
217	L	A	-0.0657
218	L	A	0.0000
219	E	A	-0.4026
220	T	A	-0.1956
221	Y	A	0.0000
222	C	A	0.0000
223	A	A	-0.7870
224	T	A	-0.6775
225	P	A	-1.1739
226	A	A	-1.3523
227	K	A	-2.3492
228	S	A	-1.9051
229	E	A	-2.0622
230	A	A	-0.9966
231	A	A	-0.8976
232	A	A	-0.6320
233	L	A	-0.2823
234	E	A	-2.2036
235	H	A	-2.5619
236	H	A	-2.7317
237	H	A	-2.9513
238	H	A	-3.0693
239	H	A	-2.6143
240	H	A	-2.1177