Project name: ad2aae5ea5f4beb

Chain sequence(s)	A: IVIVKGH; C: IVIVKGH; B: IVIVKGH; E: IVIVKGH; D: IVIVKGH; G: IVIVKGH; F: IVIVKGH; I: IVIVKGH; H: IVIVKGH; K: IVIVKGH; J: IVIVKGH; L: IVIVKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:32)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:35)

• Minimal score value: -2.5205
• Maximal score value: 4.3912
• Average score: 0.5157
• Total score value: 43.3209

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	I	A	2.7417
2	V	A	0.0000
3	I	A	1.5949
4	V	A	0.0000
5	K	A	-1.7065
6	G	A	-1.7029
7	H	A	-2.5006
1	I	B	3.0835
2	V	B	3.0383
3	I	B	2.0521
4	V	B	1.2996
5	K	B	-1.4054
6	G	B	-1.6273
7	H	B	-2.1932
1	I	C	3.4887
2	V	C	4.0716
3	I	C	3.2719
4	V	C	2.3471
5	K	C	0.4245
6	G	C	-1.0951
7	H	C	-1.8227
1	I	D	2.8517
2	V	D	3.4685
3	I	D	0.0000
4	V	D	2.0225
5	K	D	0.0000
6	G	D	-1.0923
7	H	D	-2.1625
1	I	E	2.3759
2	V	E	2.7629
3	I	E	0.0000
4	V	E	1.9232
5	K	E	0.0000
6	G	E	-1.0648
7	H	E	-2.1413
1	I	F	2.7629
2	V	F	3.3116
3	I	F	0.0000
4	V	F	2.0870
5	K	F	0.0000
6	G	F	-0.9577
7	H	F	-2.1500
1	I	G	3.1744
2	V	G	3.8102
3	I	G	2.8628
4	V	G	2.4071
5	K	G	0.9532
6	G	G	-0.7516
7	H	G	-1.6542
1	I	H	4.0657
2	V	H	4.3912
3	I	H	3.7061
4	V	H	1.8182
5	K	H	-1.3549
6	G	H	-1.8495
7	H	H	-2.2051
1	I	I	3.8262
2	V	I	0.0000
3	I	I	2.5512
4	V	I	1.1724
5	K	I	-1.3932
6	G	I	-1.7614
7	H	I	-2.5205
1	I	J	3.1640
2	V	J	0.0000
3	I	J	1.5272
4	V	J	0.0000
5	K	J	-1.7486
6	G	J	-1.6780
7	H	J	-2.3844
1	I	K	2.8319
2	V	K	0.0000
3	I	K	1.0537
4	V	K	0.0000
5	K	K	-1.6665
6	G	K	-1.7790
7	H	K	-2.3817
1	I	L	2.5492
2	V	L	0.0000
3	I	L	1.0483
4	V	L	0.0000
5	K	L	-1.6582
6	G	L	-1.7746
7	H	L	-2.3885