Project name: afcbfeeb2beda91

Chain sequence(s)	A: AQEVQQSPHCTTVPVGASVNITCSTSGGLRGIYLRQLGPQPQDIIYYEDGVVPTTDRRFRGRIDFSGSQDNLTITMHRLQLSDTGTYTCQAITEVNVYGSGTLVLVTEEQ
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:01)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:02)

• Minimal score value: -3.2455
• Maximal score value: 2.1821
• Average score: -0.7822
• Total score value: -86.045

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	A	-0.3313
2	Q	A	-1.2297
3	E	A	-2.2742
4	V	A	0.0000
5	Q	A	-1.8918
6	Q	A	-1.3298
7	S	A	-1.0009
8	P	A	-0.8772
9	H	A	-0.8624
10	C	A	0.0753
11	T	A	0.0293
12	T	A	0.3458
13	V	A	0.0000
14	P	A	-0.9625
15	V	A	-0.9913
16	G	A	-1.4593
17	A	A	-0.9695
18	S	A	-1.1674
19	V	A	0.0000
20	N	A	-1.5378
21	I	A	0.0000
22	T	A	-1.0995
23	C	A	0.0000
24	S	A	-1.9251
25	T	A	-2.0050
26	S	A	-1.7324
27	G	A	-1.3016
28	G	A	-1.3210
29	L	A	-1.7882
30	R	A	-2.5343
31	G	A	0.0000
32	I	A	0.0000
33	Y	A	0.0954
34	L	A	0.0000
35	R	A	-0.5594
36	Q	A	-0.6026
37	L	A	-0.0127
38	G	A	-0.8320
39	P	A	-0.9822
40	Q	A	-1.4627
41	P	A	-1.0763
42	Q	A	-1.2194
43	D	A	-1.1717
44	I	A	0.0000
45	I	A	0.0000
46	Y	A	0.3666
47	Y	A	-0.0787
48	E	A	-0.9738
49	D	A	-1.8240
50	G	A	-0.1666
51	V	A	1.7718
52	V	A	2.1821
53	P	A	1.0228
54	T	A	-0.0199
55	T	A	-1.3662
56	D	A	-2.1209
57	R	A	-3.0046
58	R	A	-2.1621
59	F	A	0.0000
60	R	A	-3.1849
61	G	A	-2.2737
62	R	A	-2.1130
63	I	A	-1.6417
64	D	A	-1.9931
65	F	A	-0.7223
66	S	A	-0.9610
67	G	A	-1.3199
68	S	A	-1.7712
69	Q	A	-2.1877
70	D	A	-2.8534
71	N	A	-2.4331
72	L	A	0.0000
73	T	A	-1.1870
74	I	A	0.0000
75	T	A	-1.1335
76	M	A	0.0000
77	H	A	-1.9229
78	R	A	-2.4153
79	L	A	0.0000
80	Q	A	-1.1582
81	L	A	0.1661
82	S	A	0.0585
83	D	A	0.0000
84	T	A	0.2704
85	G	A	0.2950
86	T	A	0.1421
87	Y	A	0.0000
88	T	A	0.0000
89	C	A	0.0000
90	Q	A	0.0000
91	A	A	0.0000
92	I	A	-0.5702
93	T	A	0.0000
94	E	A	-1.4788
95	V	A	0.4254
96	N	A	-0.5698
97	V	A	-0.0661
98	Y	A	0.3782
99	G	A	-0.4875
100	S	A	-0.4545
101	G	A	0.0000
102	T	A	0.0000
103	L	A	0.4676
104	V	A	0.0000
105	L	A	0.6228
106	V	A	0.1251
107	T	A	-1.1593
108	E	A	-2.8011
109	E	A	-3.2455
110	Q	A	-2.5526