Project name: afd6f5b0f146f62

Chain sequence(s)	A: QVQLVESGGGSVQAGGSLRLSCTASGFTFSSYGLGWFRQAPGQEREAVAAINSNGGSTYYADSVKGRFTISRDNAKNTVTLQMNNLKPEDTAIYYCASGDYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:15)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:16)

• Minimal score value: -3.692
• Maximal score value: 1.1159
• Average score: -0.8941
• Total score value: -100.1409

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.4898
2	V	A	-0.8381
3	Q	A	-0.9156
4	L	A	0.0000
5	V	A	1.1159
6	E	A	0.0302
7	S	A	-0.6723
8	G	A	-1.3407
9	G	A	-1.2190
10	G	A	-0.9458
11	S	A	-0.7274
12	V	A	-0.8536
13	Q	A	-1.7985
14	A	A	-1.9415
15	G	A	-1.8426
16	G	A	-1.4046
17	S	A	-1.5491
18	L	A	-1.3085
19	R	A	-2.2793
20	L	A	0.0000
21	S	A	-0.5932
22	C	A	0.0000
23	T	A	-0.2700
24	A	A	0.0000
25	S	A	-0.8592
26	G	A	-0.9955
27	F	A	-0.2769
28	T	A	-0.0851
29	F	A	0.0000
30	S	A	-0.7722
31	S	A	-0.2368
32	Y	A	0.3082
33	G	A	-0.4984
34	L	A	0.0000
35	G	A	0.0000
36	W	A	0.0000
37	F	A	-0.2043
38	R	A	0.0000
39	Q	A	-2.2128
40	A	A	-1.9538
41	P	A	-1.3263
42	G	A	-1.7964
43	Q	A	-3.0355
44	E	A	-3.6920
45	R	A	-3.3125
46	E	A	-2.4663
47	A	A	-0.5422
48	V	A	0.0000
49	A	A	0.0000
50	A	A	0.2650
51	I	A	0.0000
52	N	A	-1.0316
53	S	A	-1.0775
54	N	A	-1.9150
55	G	A	-1.6157
56	G	A	-1.2201
57	S	A	-0.7078
58	T	A	0.1210
59	Y	A	0.6746
60	Y	A	-0.2974
61	A	A	-1.0733
62	D	A	-2.2776
63	S	A	-1.6895
64	V	A	0.0000
65	K	A	-2.4362
66	G	A	-1.8600
67	R	A	-1.6510
68	F	A	0.0000
69	T	A	-0.8149
70	I	A	0.0000
71	S	A	-0.6707
72	R	A	-1.4384
73	D	A	-1.8728
74	N	A	-1.9693
75	A	A	-1.4193
76	K	A	-2.3215
77	N	A	-1.7236
78	T	A	-1.1034
79	V	A	0.0000
80	T	A	-0.8874
81	L	A	0.0000
82	Q	A	-1.5370
83	M	A	0.0000
84	N	A	-1.9354
85	N	A	-2.3074
86	L	A	0.0000
87	K	A	-2.6334
88	P	A	-1.8940
89	E	A	-2.3125
90	D	A	0.0000
91	T	A	-1.1459
92	A	A	0.0000
93	I	A	-0.4887
94	Y	A	0.0000
95	Y	A	-0.1080
96	C	A	0.0000
97	A	A	0.0000
98	S	A	0.0000
99	G	A	-0.9077
100	D	A	-1.5529
101	Y	A	-0.2139
102	W	A	0.1296
103	G	A	0.0664
104	Q	A	-0.8469
105	G	A	-0.4369
106	T	A	-0.7131
107	Q	A	-1.3003
108	V	A	0.0000
109	T	A	-1.0005
110	V	A	0.0000
111	S	A	-1.2652
112	S	A	-0.9223