Project name: afffa5d7eec5392

Chain sequence(s)	C: DIQLTQSPASLAVSLGQRATISCKASQSVDYDGDSYLNWYQQIPGQPPKLLIYDASNLVSGIPPRFSGSGSGTDFTLNIHPVEKVDAATYHCQQSTEDPWTFGGGTKLEIKGGGGSGGGGSGGGGSQVQLQQSGAELVRPGSSVKISCKASGYAFSSYWMNWVKQRPGQGLEWIGQIWPGDGDTNYNGKFKGKATLTADESSSTAYMQLSSLASEDSAVYFCARRETTTVGRYYYAMDYWGQGTTVTVSS
Selected Chain(s)	C
Distance of aggregation	10 Å
FoldX usage	No
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with C chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       runJob:   FoldX not utilized. Treating input pdb file as it was already optimized.    (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:01)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:02)

• Minimal score value: -2.9252
• Maximal score value: 1.8264
• Average score: -0.762
• Total score value: -190.5008

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
2	D	C	-2.6974
3	I	C	0.0000
4	Q	C	-2.2472
5	L	C	0.0000
6	T	C	-1.4008
7	Q	C	-1.1516
8	S	C	-0.7401
9	P	C	-0.4635
10	A	C	-0.5281
11	S	C	-0.9170
12	L	C	-0.5405
13	A	C	-1.0410
14	V	C	-1.1297
15	S	C	-1.4380
16	L	C	-0.7945
17	G	C	-1.0588
18	Q	C	-1.9633
19	R	C	-2.4820
20	A	C	0.0000
21	T	C	-0.7784
22	I	C	0.0000
23	S	C	-0.9976
24	C	C	0.0000
25	K	C	-2.9252
26	A	C	-2.1341
27	S	C	-2.0114
28	Q	C	-2.2672
29	S	C	-1.2948
30	V	C	0.0000
31	D	C	-0.8727
32	Y	C	-0.2015
33	D	C	-1.6687
34	G	C	-1.2965
35	D	C	-0.9336
36	S	C	0.0000
37	Y	C	0.0792
38	L	C	0.0000
39	N	C	0.0000
40	W	C	0.0000
41	Y	C	0.0000
42	Q	C	0.0000
43	Q	C	-0.5762
44	I	C	-0.3932
45	P	C	-0.6389
46	G	C	-1.1505
47	Q	C	-1.6072
48	P	C	-0.9308
49	P	C	0.0000
50	K	C	-0.5666
51	L	C	0.0000
52	L	C	0.0000
53	I	C	0.0000
54	Y	C	0.4400
55	D	C	0.0000
56	A	C	0.0000
57	S	C	-0.5773
58	N	C	-0.5769
59	L	C	0.1713
60	V	C	0.1779
61	S	C	-0.3365
62	G	C	-0.7168
63	I	C	-0.1641
64	P	C	-0.2958
65	P	C	-0.4034
66	R	C	-0.9384
67	F	C	0.0000
68	S	C	-0.5287
69	G	C	-0.4776
70	S	C	-0.8939
71	G	C	-1.3715
72	S	C	-1.0472
73	G	C	-1.4730
74	T	C	-2.1004
75	D	C	-2.8398
76	F	C	0.0000
77	T	C	-0.9646
78	L	C	0.0000
79	N	C	-0.9113
80	I	C	0.0000
81	H	C	-1.8343
82	P	C	-1.4809
83	V	C	0.0000
84	E	C	-1.6657
85	K	C	-2.5538
86	V	C	-1.3052
87	D	C	0.0000
88	A	C	-1.3704
89	A	C	0.0000
90	T	C	-0.8235
91	Y	C	0.0000
92	H	C	0.0000
93	C	C	0.0000
94	Q	C	0.0000
95	Q	C	0.0000
96	S	C	0.0000
97	T	C	-0.7697
98	E	C	-2.0066
99	D	C	-2.1091
100	P	C	-1.8301
101	W	C	0.0000
102	T	C	-1.1033
103	F	C	0.0000
104	G	C	0.0000
105	G	C	-1.1523
106	G	C	-0.9325
107	T	C	0.0000
108	K	C	-1.7178
109	L	C	0.0000
110	E	C	-2.3504
111	I	C	0.0000
112	K	C	-2.4565
113	G	C	-1.8100
114	G	C	-1.5770
115	G	C	-2.0283
116	G	C	-1.9567
117	S	C	-1.2266
118	G	C	-1.2496
119	G	C	-1.4383
120	G	C	-1.3085
121	G	C	-1.3266
122	S	C	-0.8233
123	G	C	-1.1315
124	G	C	-1.1180
125	G	C	-1.2480
126	G	C	-1.4002
127	S	C	-1.3106
128	Q	C	-1.8144
129	V	C	-1.2952
130	Q	C	-2.1672
131	L	C	0.0000
132	Q	C	-2.3248
133	Q	C	0.0000
134	S	C	-1.2152
135	G	C	-0.9259
136	A	C	-0.2305
137	E	C	-0.3447
138	L	C	0.8092
139	V	C	-0.3240
140	R	C	-1.8332
141	P	C	-1.5163
142	G	C	-1.1858
143	S	C	-0.9991
144	S	C	-1.1825
145	V	C	0.0000
146	K	C	-1.9796
147	I	C	0.0000
148	S	C	-1.0933
149	C	C	0.0000
150	K	C	-2.3929
151	A	C	0.0000
152	S	C	-1.3598
153	G	C	-1.0788
154	Y	C	-0.5159
155	A	C	-0.2147
156	F	C	0.0000
157	S	C	-1.0466
158	S	C	-0.6300
159	Y	C	0.0000
160	W	C	-0.0471
161	M	C	0.0000
162	N	C	0.0000
163	W	C	0.0000
164	V	C	0.0000
165	K	C	0.0000
166	Q	C	-0.9997
167	R	C	-1.6711
168	P	C	-1.1606
169	G	C	-1.3972
170	Q	C	-1.9990
171	G	C	-1.3412
172	L	C	0.0000
173	E	C	-1.0024
174	W	C	0.0000
175	I	C	0.0000
176	G	C	0.0000
177	Q	C	0.0000
178	I	C	0.0000
179	W	C	-0.7464
180	P	C	0.0000
181	G	C	-1.9121
182	D	C	-2.7973
183	G	C	-2.1469
184	D	C	-2.4249
185	T	C	-1.2305
186	N	C	-1.2037
187	Y	C	-1.2143
188	N	C	0.0000
189	G	C	-2.3529
190	K	C	-2.5374
191	F	C	0.0000
192	K	C	-2.7506
193	G	C	-1.8376
194	K	C	-1.7160
195	A	C	0.0000
196	T	C	-0.9088
197	L	C	0.0000
198	T	C	-0.7988
199	A	C	-1.4388
200	D	C	-2.0413
201	E	C	-2.6215
202	S	C	-1.3450
203	S	C	-1.2893
204	S	C	-1.4810
205	T	C	0.0000
206	A	C	0.0000
207	Y	C	-0.6007
208	M	C	0.0000
209	Q	C	-1.3282
210	L	C	0.0000
211	S	C	-0.9618
212	S	C	-0.8486
213	L	C	0.0000
214	A	C	-1.2912
215	S	C	-1.4796
216	E	C	-2.0491
217	D	C	0.0000
218	S	C	-0.7262
219	A	C	0.0000
220	V	C	-0.0413
221	Y	C	0.0000
222	F	C	0.0000
223	C	C	0.0000
224	A	C	0.0000
225	R	C	0.0000
226	R	C	0.0000
227	E	C	-0.7284
228	T	C	-0.2555
229	T	C	0.2944
230	T	C	0.8342
231	V	C	1.8264
232	G	C	0.9688
233	R	C	0.2968
234	Y	C	1.0318
235	Y	C	0.7603
236	Y	C	0.5826
237	A	C	0.0000
238	M	C	0.0000
239	D	C	-0.4453
240	Y	C	-0.4040
241	W	C	-0.5962
242	G	C	0.0000
243	Q	C	-1.5487
244	G	C	-0.8490
245	T	C	0.0000
246	T	C	-0.1714
247	V	C	0.0000
248	T	C	-0.1583
249	V	C	0.0000
250	S	C	-0.6199
251	S	C	-0.7154