Project name: b154ff2864b3f15

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGFSFGDSDMAWVRQAPGKGLEWVSRITSDGSSTDYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAKTEELLYQNSIDDWGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:30)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:30)

• Minimal score value: -2.777
• Maximal score value: 1.871
• Average score: -0.6759
• Total score value: -81.7899

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.0502
2	V	H	-1.3326
3	Q	H	-1.2748
4	L	H	0.0000
5	V	H	1.2185
6	E	H	0.0000
7	S	H	-0.2193
8	G	H	-0.8033
9	G	H	0.0330
10	G	H	0.5475
11	L	H	1.2961
12	V	H	0.0000
13	Q	H	-1.4556
14	P	H	-1.6900
15	G	H	-1.4941
16	G	H	-1.0878
17	S	H	-1.3111
18	L	H	-1.0053
19	R	H	-2.0724
20	L	H	0.0000
21	S	H	-0.3676
22	C	H	0.0000
23	A	H	-0.0565
24	A	H	0.0000
25	S	H	-0.9786
26	G	H	-1.2396
27	F	H	-0.9862
28	S	H	-1.0429
29	F	H	0.0000
30	G	H	-2.2404
31	D	H	-2.6490
32	S	H	0.0000
33	D	H	0.0000
34	M	H	0.0000
35	A	H	0.0000
36	W	H	0.0000
37	V	H	0.0000
38	R	H	0.0000
39	Q	H	-0.3220
40	A	H	-0.9627
41	P	H	-0.9218
42	G	H	-1.5628
43	K	H	-2.0936
44	G	H	-0.9739
45	L	H	0.6005
46	E	H	-0.2675
47	W	H	0.3898
48	V	H	0.0000
49	S	H	0.0000
50	R	H	-0.5525
51	I	H	0.0000
52	T	H	-1.2138
52A	S	H	-2.0291
53	D	H	-2.6268
54	G	H	-1.5547
55	S	H	-0.9636
56	S	H	-0.8705
57	T	H	-0.7361
58	D	H	-1.4259
59	Y	H	-1.3439
60	A	H	-1.5547
61	D	H	-2.6118
62	S	H	-1.7479
63	V	H	0.0000
64	K	H	-2.7770
65	G	H	-1.7632
66	R	H	-1.5003
67	F	H	0.0000
68	T	H	-0.9280
69	I	H	0.0000
70	S	H	-0.4774
71	R	H	-1.2846
72	D	H	-1.8676
73	N	H	-2.6643
74	S	H	-1.8192
75	K	H	-2.4959
76	N	H	-1.9692
77	T	H	0.0000
78	L	H	0.0000
79	Y	H	-0.4567
80	L	H	0.0000
81	Q	H	-1.1160
82	M	H	0.0000
82A	N	H	-1.3924
82B	S	H	-1.2385
82C	L	H	0.0000
83	R	H	-2.3511
84	A	H	-1.7619
85	E	H	-2.2342
86	D	H	0.0000
87	T	H	-0.4312
88	A	H	0.0000
89	V	H	0.9173
90	Y	H	0.0000
91	Y	H	0.6745
92	C	H	0.0000
93	A	H	0.0000
94	K	H	0.0000
95	T	H	0.0000
96	E	H	-1.9031
97	E	H	-0.9411
98	L	H	0.6270
99	L	H	1.8710
100	Y	H	1.4858
100A	Q	H	-0.1193
100B	N	H	-1.1093
100C	S	H	-0.9592
100D	I	H	-1.0559
101	D	H	-2.0601
102	D	H	-1.3687
103	W	H	-0.2310
104	G	H	-0.1318
105	Q	H	-0.6272
106	G	H	0.1787
107	T	H	0.6299
108	L	H	1.5507
109	V	H	0.0000
110	T	H	0.2654
111	V	H	0.0000
112	S	H	-0.7624
113	S	H	-0.5849