Project name: b15f55242c56157

Chain sequence(s)	A: QVQLVQSGAEAEVKKPGASVKVSCKASGYTFSMHWVRQAPGQGLEWMGRIDPNSGGTNYRVTSTRDTSISTAYMELSRLRSDDTAVYYCARAAYHCRHNYGQWKWGQGTLVTVSSAAAHHH
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:12)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:12)

• Minimal score value: -3.477
• Maximal score value: 1.4041
• Average score: -0.6372
• Total score value: -77.0991

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	A	-1.3997
2	V	A	-0.6948
3	Q	A	-1.4919
4	L	A	0.0000
5	V	A	-0.1093
6	Q	A	0.0000
7	S	A	-1.0023
8	G	A	-1.3943
9	A	A	-1.1791
10	E	A	-1.9580
11	A	A	-0.8348
12	E	A	-1.1212
13	V	A	-0.1606
14	K	A	-1.3273
15	K	A	-2.4416
16	P	A	-2.5698
17	G	A	-2.3260
18	A	A	-1.7700
19	S	A	-1.8790
20	V	A	0.0000
21	K	A	-2.1401
22	V	A	0.0000
23	S	A	-0.7374
24	C	A	0.0000
25	K	A	-0.8032
26	A	A	0.0000
27	S	A	-0.4475
28	G	A	-0.3849
29	Y	A	1.1452
30	T	A	0.3975
31	F	A	0.5983
32	S	A	-0.3519
33	M	A	0.0000
34	H	A	-0.2298
35	W	A	0.0000
36	V	A	0.0000
37	R	A	-0.0244
38	Q	A	-0.5249
39	A	A	-1.0920
40	P	A	-1.2017
41	G	A	-1.1998
42	Q	A	-1.7168
43	G	A	-0.7818
44	L	A	0.5462
45	E	A	-0.2902
46	W	A	0.7061
47	M	A	0.0000
48	G	A	0.0000
49	R	A	-1.0850
50	I	A	0.0000
51	D	A	-1.3070
52	P	A	-1.2354
53	N	A	-1.7429
54	S	A	-1.4110
55	G	A	-1.4324
56	G	A	-1.3010
57	T	A	-0.9992
58	N	A	-0.9402
59	Y	A	0.3656
60	R	A	-0.7817
61	V	A	0.0000
62	T	A	-0.9536
63	S	A	0.0000
64	T	A	-0.8354
65	R	A	-0.9877
66	D	A	-0.5919
67	T	A	-0.0714
68	S	A	0.4321
69	I	A	1.4041
70	S	A	0.3721
71	T	A	0.0000
72	A	A	0.0000
73	Y	A	-0.8271
74	M	A	0.0000
75	E	A	-1.4796
76	L	A	0.0000
77	S	A	-1.7446
78	R	A	-2.8855
79	L	A	0.0000
80	R	A	-3.4770
81	S	A	-2.3684
82	D	A	-2.5447
83	D	A	0.0000
84	T	A	-0.9600
85	A	A	0.0000
86	V	A	0.6138
87	Y	A	0.0000
88	Y	A	0.3906
89	C	A	0.0000
90	A	A	0.0000
91	R	A	0.0000
92	A	A	0.3181
93	A	A	0.0000
94	Y	A	0.6377
95	H	A	-0.4172
96	C	A	-0.4012
97	R	A	-1.8990
98	H	A	-1.5245
99	N	A	-1.2447
100	Y	A	0.0038
101	G	A	-0.2047
102	Q	A	-0.5136
103	W	A	0.2977
104	K	A	-0.3949
105	W	A	0.0867
106	G	A	-0.5071
107	Q	A	-0.7867
108	G	A	0.0000
109	T	A	0.0000
110	L	A	0.2261
111	V	A	0.0000
112	T	A	-0.4855
113	V	A	0.0000
114	S	A	-1.1201
115	S	A	-1.0215
116	A	A	-0.4395
117	A	A	-0.6515
118	A	A	-0.9812
119	H	A	-1.7554
120	H	A	-1.9504
121	H	A	-1.7933