| Chain sequence(s) |
A: MNRLQNKVAIITGGTKGIGYGIAKRFLAEGAKVVITGRNAEVGEAAAADLGDPSVVTYLQQDVTDEARWTEVYDQTEALYGPVTTLVNNSGIAIGKNVEDTTTEDWHTLLAINLDAVFFGTRLAIKRMKNKNLGGSIINMSSIEGFIGDPNLAAYNASKGAVRIFSKSAALHCAINDLGVRVNTVHPGYIRTPMVEGLSGFEAAMSERTKTPMGHIGDPDDIGYICVYLASDESKFATGSEFVVDGGYTAQ
C: MNRLQNKVAIITGGTKGIGYGIAKRFLAEGAKVVITGRNAEVGEAAAADLGDPSVVTYLQQDVTDEARWTEVYDQTEALYGPVTTLVNNSGIAIGKNVEDTTTEDWHTLLAINLDAVFFGTRLAIKRMKNKNLGGSIINMSSIEGFIGDPNLAAYNASKGAVRIFSKSAALHCAINDLGVRVNTVHPGYIRTPMVEGLSGFEAAMSERTKTPMGHIGDPDDIGYICVYLASDESKFATGSEFVVDGGYTAQ B: MNRLQNKVAIITGGTKGIGYGIAKRFLAEGAKVVITGRNAEVGEAAAADLGDPSVVTYLQQDVTDEARWTEVYDQTEALYGPVTTLVNNSGIAIGKNVEDTTTEDWHTLLAINLDAVFFGTRLAIKRMKNKNLGGSIINMSSIEGFIGDPNLAAYNASKGAVRIFSKSAALHCAINDLGVRVNTVHPGYIRTPMVEGLSGFEAAMSERTKTPMGHIGDPDDIGYICVYLASDESKFATGSEFVVDGGYTAQ D: MNRLQNKVAIITGGTKGIGYGIAKRFLAEGAKVVITGRNAEVGEAAAADLGDPSVVTYLQQDVTDEARWTEVYDQTEALYGPVTTLVNNSGIAIGKNVEDTTTEDWHTLLAINLDAVFFGTRLAIKRMKNKNLGGSIINMSSIEGFIGDPNLAAYNASKGAVRIFSKSAALHCAINDLGVRVNTVHPGYIRTPMVEGLSGFEAAMSERTKTPMGHIGDPDDIGYICVYLASDESKFATGSEFVVDGGYTAQ input PDB |
| Selected Chain(s) | A,C,B,D |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | No |
| Mutated residues | FN146D |
| Energy difference between WT (input) and mutated protein (by FoldX) | -0.290297 kcal/mol |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with all chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:00)
[INFO] FoldX: Building mutant model (00:05:15)
[INFO] FoldX: Starting FoldX energy minimalization (00:05:42)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:10:31)
[INFO] Main: Simulation completed successfully. (00:10:42)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 1 | M | A | 0.5865 | |
| 2 | N | A | -0.6139 | |
| 3 | R | A | -1.1539 | |
| 4 | L | A | 0.0000 | |
| 5 | Q | A | -2.1606 | |
| 6 | N | A | -2.2210 | |
| 7 | K | A | -1.4369 | |
| 8 | V | A | 0.0000 | |
| 9 | A | A | 0.0000 | |
| 10 | I | A | 0.0000 | |
| 11 | I | A | 0.0000 | |
| 12 | T | A | 0.0000 | |
| 13 | G | A | -0.9738 | |
| 14 | G | A | 0.0000 | |
| 15 | T | A | -1.0768 | |
| 16 | K | A | -0.8583 | |
| 17 | G | A | -0.5341 | |
| 18 | I | A | -0.5449 | |
| 19 | G | A | 0.0000 | |
| 20 | Y | A | -0.5405 | |
| 21 | G | A | -1.0385 | |
| 22 | I | A | 0.0000 | |
| 23 | A | A | 0.0000 | |
| 24 | K | A | -1.9409 | |
| 25 | R | A | -1.0969 | |
| 26 | F | A | 0.0000 | |
| 27 | L | A | -0.8379 | |
| 28 | A | A | -0.7425 | |
| 29 | E | A | -1.1313 | |
| 30 | G | A | -1.2068 | |
| 31 | A | A | 0.0000 | |
| 32 | K | A | -0.8907 | |
| 33 | V | A | 0.0000 | |
| 34 | V | A | 0.0000 | |
| 35 | I | A | 0.0000 | |
| 36 | T | A | 0.0000 | |
| 37 | G | A | -1.9948 | |
| 38 | R | A | -3.0460 | |
| 39 | N | A | -3.0548 | |
| 40 | A | A | -2.5408 | |
| 41 | E | A | -2.6095 | |
| 42 | V | A | -1.4763 | |
| 43 | G | A | 0.0000 | |
| 44 | E | A | -2.6163 | |
| 45 | A | A | -1.4898 | |
| 46 | A | A | 0.0000 | |
| 47 | A | A | 0.0000 | |
| 48 | A | A | -1.7661 | |
| 49 | D | A | -2.4359 | |
| 50 | L | A | -1.4615 | |
| 51 | G | A | -1.6458 | |
| 52 | D | A | -2.0311 | |
| 53 | P | A | -0.9865 | |
| 54 | S | A | -0.5568 | |
| 55 | V | A | -0.3325 | |
| 56 | V | A | 0.0000 | |
| 57 | T | A | -0.5548 | |
| 58 | Y | A | 0.0000 | |
| 59 | L | A | -1.1662 | |
| 60 | Q | A | -2.1006 | |
| 61 | Q | A | 0.0000 | |
| 62 | D | A | -1.6970 | |
| 63 | V | A | 0.0000 | |
| 64 | T | A | -0.9809 | |
| 65 | D | A | -1.6876 | |
| 66 | E | A | -1.8419 | |
| 67 | A | A | -1.4106 | |
| 68 | R | A | -2.1541 | |
| 69 | W | A | 0.0000 | |
| 70 | T | A | -1.8682 | |
| 71 | E | A | -2.8804 | |
| 72 | V | A | 0.0000 | |
| 73 | Y | A | 0.0000 | |
| 74 | D | A | -2.7872 | |
| 75 | Q | A | -1.7012 | |
| 76 | T | A | 0.0000 | |
| 77 | E | A | -1.1926 | |
| 78 | A | A | -0.3666 | |
| 79 | L | A | 0.4538 | |
| 80 | Y | A | 0.0672 | |
| 81 | G | A | -0.5646 | |
| 82 | P | A | -0.7417 | |
| 83 | V | A | 0.0000 | |
| 84 | T | A | 0.0000 | |
| 85 | T | A | 0.0000 | |
| 86 | L | A | 0.0000 | |
| 87 | V | A | 0.0000 | |
| 88 | N | A | 0.0000 | |
| 89 | N | A | -0.2251 | |
| 90 | S | A | -0.2960 | |
| 91 | G | A | 0.1639 | |
| 92 | I | A | 0.8766 | |
| 93 | A | A | 0.3248 | |
| 94 | I | A | 0.0000 | |
| 95 | G | A | -1.6375 | |
| 96 | K | A | -2.7509 | |
| 97 | N | A | -2.2980 | |
| 98 | V | A | 0.0000 | |
| 99 | E | A | -1.7861 | |
| 100 | D | A | -2.8304 | |
| 101 | T | A | 0.0000 | |
| 102 | T | A | -1.7896 | |
| 103 | T | A | -1.8048 | |
| 104 | E | A | -2.6527 | |
| 105 | D | A | -2.5599 | |
| 106 | W | A | 0.0000 | |
| 107 | H | A | -1.8171 | |
| 108 | T | A | -1.2164 | |
| 109 | L | A | 0.0000 | |
| 110 | L | A | 0.0000 | |
| 111 | A | A | -0.5293 | |
| 112 | I | A | 0.0000 | |
| 113 | N | A | 0.0000 | |
| 114 | L | A | 0.0000 | |
| 115 | D | A | -0.5441 | |
| 116 | A | A | 0.0000 | |
| 117 | V | A | 0.0000 | |
| 118 | F | A | 0.0000 | |
| 119 | F | A | 0.0000 | |
| 120 | G | A | 0.0000 | |
| 121 | T | A | 0.0000 | |
| 122 | R | A | -0.7286 | |
| 123 | L | A | -0.5185 | |
| 124 | A | A | 0.0000 | |
| 125 | I | A | 0.0000 | |
| 126 | K | A | -1.5296 | |
| 127 | R | A | -1.5619 | |
| 128 | M | A | 0.0000 | |
| 129 | K | A | -2.9674 | |
| 130 | N | A | -3.5080 | |
| 131 | K | A | -3.2603 | |
| 132 | N | A | -2.6582 | |
| 133 | L | A | -1.6571 | |
| 134 | G | A | -1.5724 | |
| 135 | G | A | 0.0000 | |
| 136 | S | A | 0.0000 | |
| 137 | I | A | 0.0000 | |
| 138 | I | A | 0.0000 | |
| 139 | N | A | 0.0000 | |
| 140 | M | A | 0.0000 | |
| 141 | S | A | 0.0000 | |
| 142 | S | A | -0.0866 | |
| 143 | I | A | 0.0000 | |
| 144 | E | A | 0.0000 | |
| 145 | G | A | 0.0000 | |
| 146 | F | A | 0.2287 | |
| 147 | I | A | 0.1446 | |
| 148 | G | A | 0.0000 | |
| 149 | D | A | -0.6555 | |
| 150 | P | A | -1.0613 | |
| 151 | N | A | -2.2858 | |
| 152 | L | A | 0.0000 | |
| 153 | A | A | 0.0000 | |
| 154 | A | A | 0.0000 | |
| 155 | Y | A | -0.0366 | |
| 156 | N | A | 0.0000 | |
| 157 | A | A | 0.0000 | |
| 158 | S | A | 0.0000 | |
| 159 | K | A | -0.2634 | |
| 160 | G | A | 0.0000 | |
| 161 | A | A | 0.0000 | |
| 162 | V | A | 0.0000 | |
| 163 | R | A | -0.2416 | |
| 164 | I | A | 0.0000 | |
| 165 | F | A | 0.0000 | |
| 166 | S | A | 0.0000 | |
| 167 | K | A | 0.0000 | |
| 168 | S | A | 0.0000 | |
| 169 | A | A | 0.0000 | |
| 170 | A | A | 0.0000 | |
| 171 | L | A | 0.0000 | |
| 172 | H | A | 0.0000 | |
| 173 | C | A | 0.0000 | |
| 174 | A | A | 0.0000 | |
| 175 | I | A | -0.8077 | |
| 176 | N | A | -2.1932 | |
| 177 | D | A | -2.6882 | |
| 178 | L | A | 0.0000 | |
| 179 | G | A | -2.5055 | |
| 180 | V | A | 0.0000 | |
| 181 | R | A | -0.7251 | |
| 182 | V | A | 0.0000 | |
| 183 | N | A | 0.0000 | |
| 184 | T | A | 0.0000 | |
| 185 | V | A | 0.0000 | |
| 186 | H | A | 0.0000 | |
| 187 | P | A | 0.0000 | |
| 188 | G | A | -0.2325 | |
| 189 | Y | A | 0.0000 | |
| 190 | I | A | 0.0000 | |
| 191 | R | A | -1.3373 | |
| 192 | T | A | 0.0000 | |
| 193 | P | A | -0.8902 | |
| 194 | M | A | -0.0920 | |
| 195 | V | A | 0.0000 | |
| 196 | E | A | -2.1012 | |
| 197 | G | A | -1.1617 | |
| 198 | L | A | -0.6910 | |
| 199 | S | A | -0.8568 | |
| 200 | G | A | -0.9306 | |
| 201 | F | A | -0.6082 | |
| 202 | E | A | -1.5779 | |
| 203 | A | A | -1.1055 | |
| 204 | A | A | -0.8924 | |
| 205 | M | A | 0.0000 | |
| 206 | S | A | -1.6892 | |
| 207 | E | A | -2.4721 | |
| 208 | R | A | -1.6074 | |
| 209 | T | A | -1.0890 | |
| 210 | K | A | -1.3206 | |
| 211 | T | A | 0.0000 | |
| 212 | P | A | 0.0000 | |
| 213 | M | A | -1.0787 | |
| 214 | G | A | -1.6023 | |
| 215 | H | A | -1.6322 | |
| 216 | I | A | 0.0000 | |
| 217 | G | A | 0.0000 | |
| 218 | D | A | -1.7583 | |
| 219 | P | A | -1.1882 | |
| 220 | D | A | -1.6060 | |
| 221 | D | A | 0.0000 | |
| 222 | I | A | 0.0000 | |
| 223 | G | A | 0.0000 | |
| 224 | Y | A | -0.4248 | |
| 225 | I | A | 0.0000 | |
| 226 | C | A | 0.0000 | |
| 227 | V | A | 0.0000 | |
| 228 | Y | A | 0.0000 | |
| 229 | L | A | 0.0000 | |
| 230 | A | A | 0.0000 | |
| 231 | S | A | 0.0000 | |
| 232 | D | A | -2.2420 | |
| 233 | E | A | -1.4169 | |
| 234 | S | A | 0.0000 | |
| 235 | K | A | -1.7612 | |
| 236 | F | A | 0.0000 | |
| 237 | A | A | 0.0000 | |
| 238 | T | A | 0.0000 | |
| 239 | G | A | 0.0000 | |
| 240 | S | A | 0.0000 | |
| 241 | E | A | -0.3471 | |
| 242 | F | A | 0.0000 | |
| 243 | V | A | 0.0000 | |
| 244 | V | A | 0.0000 | |
| 245 | D | A | 0.0000 | |
| 246 | G | A | 0.0000 | |
| 247 | G | A | 0.0000 | |
| 248 | Y | A | 0.0000 | |
| 249 | T | A | -0.1561 | |
| 250 | A | A | 0.0000 | |
| 251 | Q | A | -0.4794 | |
| 1 | M | B | 0.6400 | |
| 2 | N | B | -0.4741 | |
| 3 | R | B | -0.9874 | |
| 4 | L | B | 0.0000 | |
| 5 | Q | B | -1.8109 | |
| 6 | N | B | -2.0581 | |
| 7 | K | B | -1.3534 | |
| 8 | V | B | 0.0000 | |
| 9 | A | B | 0.0000 | |
| 10 | I | B | 0.0000 | |
| 11 | I | B | 0.0000 | |
| 12 | T | B | 0.0000 | |
| 13 | G | B | -0.9771 | |
| 14 | G | B | 0.0000 | |
| 15 | T | B | -1.4153 | |
| 16 | K | B | -1.4913 | |
| 17 | G | B | -1.0539 | |
| 18 | I | B | -0.7423 | |
| 19 | G | B | 0.0000 | |
| 20 | Y | B | -1.0187 | |
| 21 | G | B | 0.0000 | |
| 22 | I | B | 0.0000 | |
| 23 | A | B | 0.0000 | |
| 24 | K | B | -1.5331 | |
| 25 | R | B | -0.9065 | |
| 26 | F | B | 0.0000 | |
| 27 | L | B | -0.6053 | |
| 28 | A | B | -0.6248 | |
| 29 | E | B | -1.0194 | |
| 30 | G | B | -1.0743 | |
| 31 | A | B | 0.0000 | |
| 32 | K | B | -0.8568 | |
| 33 | V | B | 0.0000 | |
| 34 | V | B | 0.0000 | |
| 35 | I | B | 0.0000 | |
| 36 | T | B | 0.0000 | |
| 37 | G | B | -2.0165 | |
| 38 | R | B | -2.9184 | |
| 39 | N | B | -2.7797 | |
| 40 | A | B | -2.4175 | |
| 41 | E | B | -2.7171 | |
| 42 | V | B | -1.6203 | |
| 43 | G | B | 0.0000 | |
| 44 | E | B | -2.6252 | |
| 45 | A | B | -1.5507 | |
| 46 | A | B | 0.0000 | |
| 47 | A | B | -1.4153 | |
| 48 | A | B | -1.6810 | |
| 49 | D | B | -2.3575 | |
| 50 | L | B | -1.5396 | |
| 51 | G | B | -1.5490 | |
| 52 | D | B | -1.9548 | |
| 53 | P | B | -0.9080 | |
| 54 | S | B | -0.5148 | |
| 55 | V | B | -0.2757 | |
| 56 | V | B | 0.0000 | |
| 57 | T | B | -0.5246 | |
| 58 | Y | B | -0.5614 | |
| 59 | L | B | -1.3723 | |
| 60 | Q | B | -2.6675 | |
| 61 | Q | B | 0.0000 | |
| 62 | D | B | -1.6612 | |
| 63 | V | B | 0.0000 | |
| 64 | T | B | -0.7571 | |
| 65 | D | B | -1.3758 | |
| 66 | E | B | -1.7092 | |
| 67 | A | B | -1.5001 | |
| 68 | R | B | -2.1987 | |
| 69 | W | B | 0.0000 | |
| 70 | T | B | -1.9403 | |
| 71 | E | B | -3.1732 | |
| 72 | V | B | 0.0000 | |
| 73 | Y | B | 0.0000 | |
| 74 | D | B | -2.7202 | |
| 75 | Q | B | -1.5990 | |
| 76 | T | B | 0.0000 | |
| 77 | E | B | -1.2458 | |
| 78 | A | B | -0.3559 | |
| 79 | L | B | 0.5150 | |
| 80 | Y | B | 0.0547 | |
| 81 | G | B | -0.6335 | |
| 82 | P | B | -0.8005 | |
| 83 | V | B | 0.0000 | |
| 84 | T | B | 0.0000 | |
| 85 | T | B | 0.0000 | |
| 86 | L | B | 0.0000 | |
| 87 | V | B | 0.0000 | |
| 88 | N | B | 0.0000 | |
| 89 | N | B | -0.3622 | |
| 90 | S | B | -0.4017 | |
| 91 | G | B | -0.0279 | |
| 92 | I | B | 0.5692 | |
| 93 | A | B | 0.2556 | |
| 94 | I | B | -0.0650 | |
| 95 | G | B | -0.9825 | |
| 96 | K | B | -1.6089 | |
| 97 | N | B | -1.5892 | |
| 98 | V | B | 0.0000 | |
| 99 | E | B | -1.6217 | |
| 100 | D | B | -2.3695 | |
| 101 | T | B | 0.0000 | |
| 102 | T | B | -1.5045 | |
| 103 | T | B | -1.5209 | |
| 104 | E | B | -2.2829 | |
| 105 | D | B | -1.6891 | |
| 106 | W | B | 0.0000 | |
| 107 | H | B | -1.6698 | |
| 108 | T | B | -0.9615 | |
| 109 | L | B | 0.0000 | |
| 110 | L | B | 0.0000 | |
| 111 | A | B | -0.3959 | |
| 112 | I | B | 0.0000 | |
| 113 | N | B | 0.0000 | |
| 114 | L | B | 0.0000 | |
| 115 | D | B | -0.5169 | |
| 116 | A | B | 0.0000 | |
| 117 | V | B | 0.0000 | |
| 118 | F | B | 0.0000 | |
| 119 | F | B | 0.0000 | |
| 120 | G | B | 0.0000 | |
| 121 | T | B | 0.0000 | |
| 122 | R | B | -0.8340 | |
| 123 | L | B | -0.5624 | |
| 124 | A | B | 0.0000 | |
| 125 | I | B | 0.0000 | |
| 126 | K | B | -1.7159 | |
| 127 | R | B | -1.6980 | |
| 128 | M | B | 0.0000 | |
| 129 | K | B | -2.7630 | |
| 130 | N | B | -3.3315 | |
| 131 | K | B | -2.9800 | |
| 132 | N | B | -2.4779 | |
| 133 | L | B | -1.4270 | |
| 134 | G | B | -1.5337 | |
| 135 | G | B | 0.0000 | |
| 136 | S | B | 0.0000 | |
| 137 | I | B | 0.0000 | |
| 138 | I | B | 0.0000 | |
| 139 | N | B | 0.0000 | |
| 140 | M | B | 0.0000 | |
| 141 | S | B | 0.0000 | |
| 142 | S | B | 0.0000 | |
| 143 | I | B | 0.0000 | |
| 144 | E | B | 0.0000 | |
| 145 | G | B | 0.0000 | |
| 146 | F | B | 0.4866 | |
| 147 | I | B | 0.2784 | |
| 148 | G | B | 0.0000 | |
| 149 | D | B | 0.0000 | |
| 150 | P | B | -0.5095 | |
| 151 | N | B | -1.3191 | |
| 152 | L | B | 0.0000 | |
| 153 | A | B | 0.0000 | |
| 154 | A | B | 0.0000 | |
| 155 | Y | B | 0.0000 | |
| 156 | N | B | 0.0000 | |
| 157 | A | B | 0.0000 | |
| 158 | S | B | 0.0000 | |
| 159 | K | B | 0.0000 | |
| 160 | G | B | 0.0000 | |
| 161 | A | B | 0.0000 | |
| 162 | V | B | 0.0000 | |
| 163 | R | B | -0.1924 | |
| 164 | I | B | 0.0000 | |
| 165 | F | B | 0.0000 | |
| 166 | S | B | 0.0000 | |
| 167 | K | B | 0.0000 | |
| 168 | S | B | 0.0000 | |
| 169 | A | B | 0.0000 | |
| 170 | A | B | 0.0000 | |
| 171 | L | B | 0.0000 | |
| 172 | H | B | 0.0000 | |
| 173 | C | B | 0.0000 | |
| 174 | A | B | 0.0000 | |
| 175 | I | B | -0.5844 | |
| 176 | N | B | -1.9884 | |
| 177 | D | B | -2.5432 | |
| 178 | L | B | 0.0000 | |
| 179 | G | B | -2.2622 | |
| 180 | V | B | 0.0000 | |
| 181 | R | B | 0.0000 | |
| 182 | V | B | 0.0000 | |
| 183 | N | B | 0.0000 | |
| 184 | T | B | 0.0000 | |
| 185 | V | B | 0.0000 | |
| 186 | H | B | 0.0000 | |
| 187 | P | B | 0.0000 | |
| 188 | G | B | 0.0000 | |
| 189 | Y | B | 0.0000 | |
| 190 | I | B | 0.0000 | |
| 191 | R | B | -2.2161 | |
| 192 | T | B | -1.6720 | |
| 193 | P | B | -1.3301 | |
| 194 | M | B | -0.9451 | |
| 195 | V | B | 0.0000 | |
| 196 | E | B | -2.6894 | |
| 197 | G | B | -1.4898 | |
| 198 | L | B | 0.0000 | |
| 199 | S | B | -1.1653 | |
| 200 | G | B | -1.3478 | |
| 201 | F | B | -1.3580 | |
| 202 | E | B | -2.7747 | |
| 203 | A | B | -1.3725 | |
| 204 | A | B | -1.2407 | |
| 205 | M | B | 0.0000 | |
| 206 | S | B | -1.7315 | |
| 207 | E | B | -2.4080 | |
| 208 | R | B | -1.6180 | |
| 209 | T | B | -1.1755 | |
| 210 | K | B | -1.3306 | |
| 211 | T | B | 0.0000 | |
| 212 | P | B | 0.0000 | |
| 213 | M | B | -0.9154 | |
| 214 | G | B | -1.3608 | |
| 215 | H | B | -1.4408 | |
| 216 | I | B | 0.0000 | |
| 217 | G | B | 0.0000 | |
| 218 | D | B | -1.2766 | |
| 219 | P | B | -1.1236 | |
| 220 | D | B | -1.0206 | |
| 221 | D | B | 0.0000 | |
| 222 | I | B | 0.0000 | |
| 223 | G | B | 0.0000 | |
| 224 | Y | B | -0.3705 | |
| 225 | I | B | 0.0000 | |
| 226 | C | B | 0.0000 | |
| 227 | V | B | 0.0000 | |
| 228 | Y | B | 0.0000 | |
| 229 | L | B | 0.0000 | |
| 230 | A | B | 0.0000 | |
| 231 | S | B | 0.0000 | |
| 232 | D | B | -2.2469 | |
| 233 | E | B | 0.0000 | |
| 234 | S | B | 0.0000 | |
| 235 | K | B | -2.0905 | |
| 236 | F | B | 0.0000 | |
| 237 | A | B | 0.0000 | |
| 238 | T | B | 0.0000 | |
| 239 | G | B | 0.0000 | |
| 240 | S | B | 0.0000 | |
| 241 | E | B | -0.3193 | |
| 242 | F | B | 0.0000 | |
| 243 | V | B | 0.0000 | |
| 244 | V | B | 0.0000 | |
| 245 | D | B | 0.0000 | |
| 246 | G | B | 0.0000 | |
| 247 | G | B | 0.0000 | |
| 248 | Y | B | 0.0000 | |
| 249 | T | B | -0.1802 | |
| 250 | A | B | 0.0000 | |
| 251 | Q | B | -0.5943 | |
| 1 | M | C | 0.0906 | |
| 2 | N | C | -1.1479 | |
| 3 | R | C | 0.0000 | |
| 4 | L | C | 0.0000 | |
| 5 | Q | C | -2.2265 | |
| 6 | N | C | -2.1358 | |
| 7 | K | C | 0.0000 | |
| 8 | V | C | 0.0000 | |
| 9 | A | C | 0.0000 | |
| 10 | I | C | 0.0000 | |
| 11 | I | C | 0.0000 | |
| 12 | T | C | 0.0000 | |
| 13 | G | C | -1.0802 | |
| 14 | G | C | 0.0000 | |
| 15 | T | C | -1.1634 | |
| 16 | K | C | -1.4244 | |
| 17 | G | C | -1.0764 | |
| 18 | I | C | -0.6885 | |
| 19 | G | C | 0.0000 | |
| 20 | Y | C | -0.8679 | |
| 21 | G | C | 0.0000 | |
| 22 | I | C | 0.0000 | |
| 23 | A | C | 0.0000 | |
| 24 | K | C | -1.3620 | |
| 25 | R | C | -0.9098 | |
| 26 | F | C | 0.0000 | |
| 27 | L | C | -0.5818 | |
| 28 | A | C | -0.7689 | |
| 29 | E | C | -1.1090 | |
| 30 | G | C | -1.3545 | |
| 31 | A | C | 0.0000 | |
| 32 | K | C | -0.8388 | |
| 33 | V | C | 0.0000 | |
| 34 | V | C | 0.0000 | |
| 35 | I | C | 0.0000 | |
| 36 | T | C | 0.0000 | |
| 37 | G | C | -1.8400 | |
| 38 | R | C | -2.9841 | |
| 39 | N | C | -2.9282 | |
| 40 | A | C | -2.3800 | |
| 41 | E | C | -2.7084 | |
| 42 | V | C | -1.5945 | |
| 43 | G | C | 0.0000 | |
| 44 | E | C | -2.6096 | |
| 45 | A | C | -1.5484 | |
| 46 | A | C | 0.0000 | |
| 47 | A | C | -1.3935 | |
| 48 | A | C | -1.6703 | |
| 49 | D | C | -2.3201 | |
| 50 | L | C | -1.4816 | |
| 51 | G | C | -1.4777 | |
| 52 | D | C | -1.8927 | |
| 53 | P | C | -0.8793 | |
| 54 | S | C | -0.5139 | |
| 55 | V | C | -0.2504 | |
| 56 | V | C | 0.0000 | |
| 57 | T | C | -0.5154 | |
| 58 | Y | C | -0.5123 | |
| 59 | L | C | -1.1365 | |
| 60 | Q | C | -2.3566 | |
| 61 | Q | C | 0.0000 | |
| 62 | D | C | -2.1723 | |
| 63 | V | C | 0.0000 | |
| 64 | T | C | -1.2491 | |
| 65 | D | C | -2.1644 | |
| 66 | E | C | -2.0003 | |
| 67 | A | C | -1.4293 | |
| 68 | R | C | -2.2198 | |
| 69 | W | C | 0.0000 | |
| 70 | T | C | -1.9530 | |
| 71 | E | C | -2.6266 | |
| 72 | V | C | 0.0000 | |
| 73 | Y | C | 0.0000 | |
| 74 | D | C | -2.7903 | |
| 75 | Q | C | -1.7987 | |
| 76 | T | C | 0.0000 | |
| 77 | E | C | -1.2048 | |
| 78 | A | C | -0.5133 | |
| 79 | L | C | 0.2495 | |
| 80 | Y | C | -0.0771 | |
| 81 | G | C | -0.6696 | |
| 82 | P | C | -0.9874 | |
| 83 | V | C | 0.0000 | |
| 84 | T | C | 0.0000 | |
| 85 | T | C | 0.0000 | |
| 86 | L | C | 0.0000 | |
| 87 | V | C | 0.0000 | |
| 88 | N | C | 0.0000 | |
| 89 | N | C | -0.3411 | |
| 90 | S | C | -0.5817 | |
| 91 | G | C | 0.0671 | |
| 92 | I | C | 0.7324 | |
| 93 | A | C | 0.3334 | |
| 94 | I | C | -0.1412 | |
| 95 | G | C | -1.1392 | |
| 96 | K | C | -1.7102 | |
| 97 | N | C | -1.6550 | |
| 98 | V | C | 0.0000 | |
| 99 | E | C | -1.6437 | |
| 100 | D | C | -2.3967 | |
| 101 | T | C | 0.0000 | |
| 102 | T | C | -1.4866 | |
| 103 | T | C | -1.5863 | |
| 104 | E | C | -2.3026 | |
| 105 | D | C | -1.7227 | |
| 106 | W | C | 0.0000 | |
| 107 | H | C | -1.6289 | |
| 108 | T | C | -1.0014 | |
| 109 | L | C | 0.0000 | |
| 110 | L | C | 0.0000 | |
| 111 | A | C | -0.4692 | |
| 112 | I | C | 0.0000 | |
| 113 | N | C | 0.0000 | |
| 114 | L | C | 0.0000 | |
| 115 | D | C | -0.6844 | |
| 116 | A | C | 0.0000 | |
| 117 | V | C | 0.0000 | |
| 118 | F | C | 0.0000 | |
| 119 | F | C | 0.0000 | |
| 120 | G | C | 0.0000 | |
| 121 | T | C | 0.0000 | |
| 122 | R | C | -0.8466 | |
| 123 | L | C | -0.7403 | |
| 124 | A | C | 0.0000 | |
| 125 | I | C | 0.0000 | |
| 126 | K | C | -2.1154 | |
| 127 | R | C | -2.4533 | |
| 128 | M | C | 0.0000 | |
| 129 | K | C | -3.2625 | |
| 130 | N | C | -3.6929 | |
| 131 | K | C | -3.3942 | |
| 132 | N | C | -2.8488 | |
| 133 | L | C | -1.7511 | |
| 134 | G | C | -1.6092 | |
| 135 | G | C | 0.0000 | |
| 136 | S | C | 0.0000 | |
| 137 | I | C | 0.0000 | |
| 138 | I | C | 0.0000 | |
| 139 | N | C | 0.0000 | |
| 140 | M | C | 0.0000 | |
| 141 | S | C | 0.0000 | |
| 142 | S | C | 0.0000 | |
| 143 | I | C | 0.0000 | |
| 144 | E | C | 0.0000 | |
| 145 | G | C | 0.0000 | |
| 146 | F | C | 0.4848 | |
| 147 | I | C | 0.0000 | |
| 148 | G | C | 0.0000 | |
| 149 | D | C | -0.6478 | |
| 150 | P | C | -0.9300 | |
| 151 | N | C | -1.6264 | |
| 152 | L | C | 0.0000 | |
| 153 | A | C | 0.0000 | |
| 154 | A | C | 0.0000 | |
| 155 | Y | C | -0.0376 | |
| 156 | N | C | 0.0000 | |
| 157 | A | C | 0.0000 | |
| 158 | S | C | 0.0000 | |
| 159 | K | C | 0.0000 | |
| 160 | G | C | 0.0000 | |
| 161 | A | C | 0.0000 | |
| 162 | V | C | 0.0000 | |
| 163 | R | C | 0.0000 | |
| 164 | I | C | 0.0000 | |
| 165 | F | C | 0.0000 | |
| 166 | S | C | 0.0000 | |
| 167 | K | C | 0.0000 | |
| 168 | S | C | 0.0000 | |
| 169 | A | C | 0.0000 | |
| 170 | A | C | 0.0000 | |
| 171 | L | C | 0.0000 | |
| 172 | H | C | 0.0000 | |
| 173 | C | C | 0.0000 | |
| 174 | A | C | 0.0000 | |
| 175 | I | C | -0.8362 | |
| 176 | N | C | -2.2181 | |
| 177 | D | C | -2.8276 | |
| 178 | L | C | 0.0000 | |
| 179 | G | C | -2.4446 | |
| 180 | V | C | 0.0000 | |
| 181 | R | C | 0.0000 | |
| 182 | V | C | 0.0000 | |
| 183 | N | C | 0.0000 | |
| 184 | T | C | 0.0000 | |
| 185 | V | C | 0.0000 | |
| 186 | H | C | 0.0000 | |
| 187 | P | C | 0.0000 | |
| 188 | G | C | -0.2035 | |
| 189 | Y | C | 0.0000 | |
| 190 | I | C | 0.0000 | |
| 191 | R | C | -2.6860 | |
| 192 | T | C | 0.0000 | |
| 193 | P | C | -1.3761 | |
| 194 | M | C | -0.7270 | |
| 195 | V | C | 0.0000 | |
| 196 | E | C | -2.8354 | |
| 197 | G | C | -1.4143 | |
| 198 | L | C | -1.0044 | |
| 199 | S | C | -1.1001 | |
| 200 | G | C | -1.2515 | |
| 201 | F | C | -1.5226 | |
| 202 | E | C | -2.8211 | |
| 203 | A | C | -1.5243 | |
| 204 | A | C | -1.2674 | |
| 205 | M | C | 0.0000 | |
| 206 | S | C | -1.7966 | |
| 207 | E | C | -2.5855 | |
| 208 | R | C | -1.5961 | |
| 209 | T | C | -1.2208 | |
| 210 | K | C | -1.4342 | |
| 211 | T | C | 0.0000 | |
| 212 | P | C | 0.0000 | |
| 213 | M | C | -0.9477 | |
| 214 | G | C | -1.4913 | |
| 215 | H | C | -1.6195 | |
| 216 | I | C | 0.0000 | |
| 217 | G | C | 0.0000 | |
| 218 | D | C | -1.2617 | |
| 219 | P | C | -1.0881 | |
| 220 | D | C | -0.9343 | |
| 221 | D | C | 0.0000 | |
| 222 | I | C | 0.0000 | |
| 223 | G | C | 0.0000 | |
| 224 | Y | C | -0.3349 | |
| 225 | I | C | 0.0000 | |
| 226 | C | C | 0.0000 | |
| 227 | V | C | 0.0000 | |
| 228 | Y | C | 0.0000 | |
| 229 | L | C | 0.0000 | |
| 230 | A | C | 0.0000 | |
| 231 | S | C | 0.0000 | |
| 232 | D | C | -2.1704 | |
| 233 | E | C | 0.0000 | |
| 234 | S | C | 0.0000 | |
| 235 | K | C | -1.9587 | |
| 236 | F | C | 0.0000 | |
| 237 | A | C | 0.0000 | |
| 238 | T | C | 0.0000 | |
| 239 | G | C | 0.0000 | |
| 240 | S | C | 0.0000 | |
| 241 | E | C | -0.2035 | |
| 242 | F | C | 0.0000 | |
| 243 | V | C | 0.1289 | |
| 244 | V | C | 0.0000 | |
| 245 | D | C | 0.0000 | |
| 246 | G | C | 0.0000 | |
| 247 | G | C | 0.0000 | |
| 248 | Y | C | -0.1843 | |
| 249 | T | C | 0.0000 | |
| 250 | A | C | 0.0000 | |
| 251 | Q | C | -0.4585 | |
| 1 | M | D | 0.3470 | |
| 2 | N | D | -0.9911 | |
| 3 | R | D | -1.0893 | |
| 4 | L | D | 0.0000 | |
| 5 | Q | D | -2.2489 | |
| 6 | N | D | -2.3166 | |
| 7 | K | D | -1.6471 | |
| 8 | V | D | 0.0000 | |
| 9 | A | D | 0.0000 | |
| 10 | I | D | 0.0000 | |
| 11 | I | D | 0.0000 | |
| 12 | T | D | 0.0000 | |
| 13 | G | D | -1.0893 | |
| 14 | G | D | 0.0000 | |
| 15 | T | D | -1.3344 | |
| 16 | K | D | -1.3930 | |
| 17 | G | D | -1.1417 | |
| 18 | I | D | -0.7403 | |
| 19 | G | D | 0.0000 | |
| 20 | Y | D | -0.7561 | |
| 21 | G | D | 0.0000 | |
| 22 | I | D | 0.0000 | |
| 23 | A | D | 0.0000 | |
| 24 | K | D | -1.3271 | |
| 25 | R | D | -0.7883 | |
| 26 | F | D | 0.0000 | |
| 27 | L | D | -0.7329 | |
| 28 | A | D | -0.5042 | |
| 29 | E | D | 0.0000 | |
| 30 | G | D | -1.2312 | |
| 31 | A | D | 0.0000 | |
| 32 | K | D | -0.8784 | |
| 33 | V | D | 0.0000 | |
| 34 | V | D | 0.0000 | |
| 35 | I | D | 0.0000 | |
| 36 | T | D | 0.0000 | |
| 37 | G | D | -1.9174 | |
| 38 | R | D | -2.8421 | |
| 39 | N | D | -2.5809 | |
| 40 | A | D | -2.2779 | |
| 41 | E | D | -2.6534 | |
| 42 | V | D | -1.5806 | |
| 43 | G | D | 0.0000 | |
| 44 | E | D | -2.5764 | |
| 45 | A | D | -1.5287 | |
| 46 | A | D | 0.0000 | |
| 47 | A | D | 0.0000 | |
| 48 | A | D | -1.7766 | |
| 49 | D | D | -2.3826 | |
| 50 | L | D | -1.5507 | |
| 51 | G | D | -1.6709 | |
| 52 | D | D | -2.1370 | |
| 53 | P | D | -1.0131 | |
| 54 | S | D | -0.6225 | |
| 55 | V | D | -0.5351 | |
| 56 | V | D | 0.0000 | |
| 57 | T | D | -0.5289 | |
| 58 | Y | D | -0.4787 | |
| 59 | L | D | -1.0256 | |
| 60 | Q | D | -2.1751 | |
| 61 | Q | D | 0.0000 | |
| 62 | D | D | -1.9974 | |
| 63 | V | D | 0.0000 | |
| 64 | T | D | -1.0527 | |
| 65 | D | D | -1.8390 | |
| 66 | E | D | -1.5572 | |
| 67 | A | D | -1.2642 | |
| 68 | R | D | -2.2445 | |
| 69 | W | D | 0.0000 | |
| 70 | T | D | -2.0583 | |
| 71 | E | D | -2.9567 | |
| 72 | V | D | 0.0000 | |
| 73 | Y | D | 0.0000 | |
| 74 | D | D | -2.8698 | |
| 75 | Q | D | -1.8073 | |
| 76 | T | D | 0.0000 | |
| 77 | E | D | -1.3321 | |
| 78 | A | D | -0.4933 | |
| 79 | L | D | 0.2578 | |
| 80 | Y | D | 0.0000 | |
| 81 | G | D | -0.6991 | |
| 82 | P | D | -0.9610 | |
| 83 | V | D | 0.0000 | |
| 84 | T | D | 0.0000 | |
| 85 | T | D | 0.0000 | |
| 86 | L | D | 0.0000 | |
| 87 | V | D | 0.0000 | |
| 88 | N | D | 0.0000 | |
| 89 | N | D | -0.1786 | |
| 90 | S | D | -0.3883 | |
| 91 | G | D | 0.0169 | |
| 92 | I | D | 0.6297 | |
| 93 | A | D | 0.1823 | |
| 94 | I | D | -0.1634 | |
| 95 | G | D | -1.0758 | |
| 96 | K | D | -1.7816 | |
| 97 | N | D | -1.7722 | |
| 98 | V | D | 0.0000 | |
| 99 | E | D | -1.7394 | |
| 100 | D | D | -2.4516 | |
| 101 | T | D | 0.0000 | |
| 102 | T | D | -1.5409 | |
| 103 | T | D | -1.5929 | |
| 104 | E | D | -2.3234 | |
| 105 | D | D | -1.7245 | |
| 106 | W | D | 0.0000 | |
| 107 | H | D | -1.7594 | |
| 108 | T | D | -0.9933 | |
| 109 | L | D | 0.0000 | |
| 110 | L | D | 0.0000 | |
| 111 | A | D | -0.4672 | |
| 112 | I | D | 0.0000 | |
| 113 | N | D | 0.0000 | |
| 114 | L | D | 0.0000 | |
| 115 | D | D | -0.5974 | |
| 116 | A | D | 0.0000 | |
| 117 | V | D | 0.0000 | |
| 118 | F | D | 0.0000 | |
| 119 | F | D | 0.0000 | |
| 120 | G | D | 0.0000 | |
| 121 | T | D | 0.0000 | |
| 122 | R | D | -0.8869 | |
| 123 | L | D | -0.7312 | |
| 124 | A | D | 0.0000 | |
| 125 | I | D | 0.0000 | |
| 126 | K | D | -2.0620 | |
| 127 | R | D | -2.8394 | |
| 128 | M | D | 0.0000 | |
| 129 | K | D | -3.3082 | |
| 130 | N | D | -3.6842 | |
| 131 | K | D | -3.4364 | |
| 132 | N | D | -2.6379 | |
| 133 | L | D | -1.4643 | |
| 134 | G | D | -1.6315 | |
| 135 | G | D | 0.0000 | |
| 136 | S | D | 0.0000 | |
| 137 | I | D | 0.0000 | |
| 138 | I | D | 0.0000 | |
| 139 | N | D | 0.0000 | |
| 140 | M | D | 0.0000 | |
| 141 | S | D | 0.0000 | |
| 142 | S | D | 0.0000 | |
| 143 | I | D | 0.0000 | |
| 144 | E | D | 0.0000 | |
| 145 | G | D | 0.0000 | |
| 146 | N | D | -0.4008 | mutated: FN146D |
| 147 | I | D | -0.1445 | |
| 148 | G | D | 0.0000 | |
| 149 | D | D | 0.0000 | |
| 150 | P | D | -0.5534 | |
| 151 | N | D | -1.3586 | |
| 152 | L | D | 0.0000 | |
| 153 | A | D | 0.0000 | |
| 154 | A | D | 0.0000 | |
| 155 | Y | D | 0.0000 | |
| 156 | N | D | 0.0000 | |
| 157 | A | D | 0.0000 | |
| 158 | S | D | 0.0000 | |
| 159 | K | D | 0.0000 | |
| 160 | G | D | 0.0000 | |
| 161 | A | D | 0.0000 | |
| 162 | V | D | 0.0000 | |
| 163 | R | D | -0.2029 | |
| 164 | I | D | 0.0000 | |
| 165 | F | D | 0.0000 | |
| 166 | S | D | 0.0000 | |
| 167 | K | D | 0.0000 | |
| 168 | S | D | 0.0000 | |
| 169 | A | D | 0.0000 | |
| 170 | A | D | 0.0000 | |
| 171 | L | D | 0.0000 | |
| 172 | H | D | 0.0000 | |
| 173 | C | D | 0.0000 | |
| 174 | A | D | 0.0000 | |
| 175 | I | D | -0.4871 | |
| 176 | N | D | -1.9705 | |
| 177 | D | D | -2.5263 | |
| 178 | L | D | 0.0000 | |
| 179 | G | D | -2.3175 | |
| 180 | V | D | 0.0000 | |
| 181 | R | D | 0.0000 | |
| 182 | V | D | 0.0000 | |
| 183 | N | D | 0.0000 | |
| 184 | T | D | 0.0000 | |
| 185 | V | D | 0.0000 | |
| 186 | H | D | 0.0000 | |
| 187 | P | D | 0.0000 | |
| 188 | G | D | 0.0000 | |
| 189 | Y | D | 0.0000 | |
| 190 | I | D | 0.0000 | |
| 191 | R | D | -2.3472 | |
| 192 | T | D | 0.0000 | |
| 193 | P | D | -1.3856 | |
| 194 | M | D | -0.9218 | |
| 195 | V | D | 0.0000 | |
| 196 | E | D | -2.7064 | |
| 197 | G | D | -1.5458 | |
| 198 | L | D | -1.1605 | |
| 199 | S | D | -1.1959 | |
| 200 | G | D | -1.4218 | |
| 201 | F | D | 0.0000 | |
| 202 | E | D | -2.9094 | |
| 203 | A | D | -1.5064 | |
| 204 | A | D | -1.3544 | |
| 205 | M | D | 0.0000 | |
| 206 | S | D | -1.8446 | |
| 207 | E | D | -2.5070 | |
| 208 | R | D | -1.6679 | |
| 209 | T | D | -1.1203 | |
| 210 | K | D | -1.3542 | |
| 211 | T | D | 0.0000 | |
| 212 | P | D | 0.0000 | |
| 213 | M | D | -1.0447 | |
| 214 | G | D | -1.4563 | |
| 215 | H | D | -1.5565 | |
| 216 | I | D | 0.0000 | |
| 217 | G | D | 0.0000 | |
| 218 | D | D | -1.5288 | |
| 219 | P | D | -1.3162 | |
| 220 | D | D | -1.4646 | |
| 221 | D | D | 0.0000 | |
| 222 | I | D | 0.0000 | |
| 223 | G | D | 0.0000 | |
| 224 | Y | D | -0.3607 | |
| 225 | I | D | 0.0000 | |
| 226 | C | D | 0.0000 | |
| 227 | V | D | 0.0000 | |
| 228 | Y | D | 0.0000 | |
| 229 | L | D | 0.0000 | |
| 230 | A | D | 0.0000 | |
| 231 | S | D | 0.0000 | |
| 232 | D | D | -2.2365 | |
| 233 | E | D | 0.0000 | |
| 234 | S | D | 0.0000 | |
| 235 | K | D | -1.8781 | |
| 236 | F | D | 0.0000 | |
| 237 | A | D | 0.0000 | |
| 238 | T | D | 0.0000 | |
| 239 | G | D | 0.0000 | |
| 240 | S | D | 0.0000 | |
| 241 | E | D | -0.3023 | |
| 242 | F | D | 0.0000 | |
| 243 | V | D | 0.1071 | |
| 244 | V | D | 0.0000 | |
| 245 | D | D | 0.0000 | |
| 246 | G | D | 0.0000 | |
| 247 | G | D | 0.0000 | |
| 248 | Y | D | 0.0000 | |
| 249 | T | D | -0.1742 | |
| 250 | A | D | 0.0000 | |
| 251 | Q | D | -0.3980 |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine