Project name: b34f28cc7f1e965

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGRTFSVDAMGWLRQAPGKEREFVVVIDWTGGSTAYADSVKGRFTISRDNARNTVYLQMNNLKPEDTGVYYCAARERSRTAYDYWGQGTLVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:58)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:00)

• Minimal score value: -3.5606
• Maximal score value: 1.6339
• Average score: -0.7367
• Total score value: -87.6723

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.0748
2	V	A	-1.1583
3	Q	A	-0.9297
4	L	A	0.0000
5	V	A	0.8849
6	E	A	0.0000
7	S	A	-0.2217
8	G	A	-0.9596
9	G	A	0.0048
10	G	A	0.5848
11	L	A	1.3583
12	V	A	0.0000
13	Q	A	-1.5661
14	P	A	-1.9972
15	G	A	-1.8166
16	G	A	-1.2896
17	S	A	-1.6437
18	L	A	-1.3446
19	R	A	-2.3509
20	L	A	0.0000
21	S	A	-0.5320
22	C	A	0.0000
23	A	A	-0.1585
24	A	A	0.0000
25	S	A	-1.0727
26	G	A	-1.4296
27	R	A	-1.1389
28	T	A	-0.4045
29	F	A	0.0000
30	S	A	-0.4499
31	V	A	0.2846
32	D	A	0.0000
33	A	A	0.0000
34	M	A	0.0000
35	G	A	0.0000
36	W	A	0.0000
37	L	A	0.0783
38	R	A	0.0000
39	Q	A	-1.6544
40	A	A	0.0000
41	P	A	-1.3710
42	G	A	-1.9410
43	K	A	-3.3432
44	E	A	-3.5606
45	R	A	-2.5184
46	E	A	-1.8391
47	F	A	0.0965
48	V	A	0.0000
49	V	A	0.0000
50	V	A	0.3372
51	I	A	0.0000
52	D	A	-0.3966
53	W	A	0.0341
54	T	A	-0.1782
55	G	A	-0.5226
56	G	A	-0.6812
57	S	A	-0.4764
58	T	A	-0.1648
59	A	A	-0.1875
60	Y	A	-0.6034
61	A	A	-1.0914
62	D	A	-2.4139
63	S	A	-1.7215
64	V	A	0.0000
65	K	A	-2.6332
66	G	A	-1.8774
67	R	A	-1.8947
68	F	A	0.0000
69	T	A	-0.9466
70	I	A	0.0000
71	S	A	-0.5606
72	R	A	-0.9262
73	D	A	-1.3700
74	N	A	-1.2978
75	A	A	-1.3242
76	R	A	-2.3364
77	N	A	-1.6116
78	T	A	-0.9672
79	V	A	0.0000
80	Y	A	-0.6353
81	L	A	0.0000
82	Q	A	-1.6435
83	M	A	0.0000
84	N	A	-1.9075
85	N	A	-2.2516
86	L	A	0.0000
87	K	A	-2.6386
88	P	A	-1.9900
89	E	A	-2.3781
90	D	A	0.0000
91	T	A	-0.4873
92	G	A	0.0000
93	V	A	0.7381
94	Y	A	0.0000
95	Y	A	0.3041
96	C	A	0.0000
97	A	A	0.0000
98	A	A	0.0000
99	R	A	-1.6665
100	E	A	-1.9910
101	R	A	-2.3783
102	S	A	-1.9915
103	R	A	-2.7395
104	T	A	-1.4920
105	A	A	-0.9872
106	Y	A	0.0000
107	D	A	-0.8031
108	Y	A	-0.1329
109	W	A	0.2537
110	G	A	0.0000
111	Q	A	-0.6206
112	G	A	0.0000
113	T	A	0.6362
114	L	A	1.6339
115	V	A	0.0000
116	T	A	0.2985
117	V	A	0.0000
118	S	A	-0.8830
119	S	A	-0.6328