| Chain sequence(s) |
A: LAFSPPFYPSPWANGQGEWAEAYQRAVAIVSQMTLDEKVNLTTGTGWELEKCVGQTGGVPRLNIGGMCLQDSPLGIRDSDYNSAFPAGVNVAATWDKNLAYLRGQAMGQEFSDKGIDVQLGPAAGPLGRSPDGGRNWEGFSPDPALTGVLFAETIKGIQDAGVVATAKHYILNEQEHFRQVAEAAGYGFNISDTISSNVDDKTIHEMYLWPFADAVRAGVGAIMCSYNQINNSYGCQNSYTLNKLLKAELGFQGFVMSDWGAHHSGVGSALAGLDMSMPGDITFDSATSFWGTNLTIAVLNGTVPQWRVDDMAVRIMAAYYKVGRDRLYQPPNFSSWTRDEYGFKYFYPQEGPYEKVNHFVNVQRNHSEVIRKLGADSTVLLKNNNALPLTGKERKVAILGEDAGSNSYGANGCSDRGCDNGTLAMAWGSGTAEFPYLVTPEQAIQAEVLKHKGSVYAITDNWALSQVETLAKQASVSLVFVNSDAGEGYISVDGNEGDRNNLTLWKNGDNLIKAAANNCNNTIVVIHSVGPVLVDEWYDHPNVTAILWAGLPGQESGNSLADVLYGRVNPGAKSPFTWGKTREAYGDYLVRELNNGNGAPQDDFSEGVFIDYRGFDKRNETPIYEFGHGLSYTTFNYSGLHIQVLNAVATETGAAPTFGQVGNASDYVYPEGLTRISKFIYPWLNSTDLKASSGDPYYGVDTAEHVPEGATDGSPQPVLPAGGGSGGNPRLYDELIRVSVTVKNTGRVAGDAVPQLYVSLGGPNEPKVVLRKFDRLTLKPSEETVWTTTLTRRDLSNWDVAAQDWVITSYPKKVHVGSSSRQLPLHAALPKVQ
input PDB |
| Selected Chain(s) | A |
| Distance of aggregation | 10 Å |
| FoldX usage | Yes |
| Dynamic mode | No |
| Automated mutations | Yes |
| Downloads | Download all the data |
| Simulation log |
[INFO] Logger: Verbosity set to: 2 - [INFO] (00:00:00)
[WARNING] runJob: Working directory already exists (possibly overwriting previous results -ow
to prevent this behavior) (00:00:00)
[INFO] runJob: Starting aggrescan3d job on: input.pdb with A chain(s) selected (00:00:00)
[INFO] runJob: Creating pdb object from: input.pdb (00:00:00)
[INFO] FoldX: Starting FoldX energy minimalization (00:00:00)
[INFO] Analysis: Starting Aggrescan3D on folded.pdb (00:06:07)
[INFO] Auto_mut: Residue number 24 from chain A and a score of 2.083 (phenylalanine)
selected for automated muatation (00:06:15)
[INFO] Auto_mut: Residue number 22 from chain A and a score of 1.870 (leucine) selected for
automated muatation (00:06:15)
[INFO] Auto_mut: Residue number 675 from chain A and a score of 1.304 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 23 from chain A and a score of 1.292 (alanine) selected for
automated muatation (00:06:15)
[INFO] Auto_mut: Residue number 812 from chain A and a score of 1.232 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 478 from chain A and a score of 0.913 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 25 from chain A and a score of 0.866 (serine) selected for
automated muatation (00:06:15)
[INFO] Auto_mut: Residue number 430 from chain A and a score of 0.715 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 303 from chain A and a score of 0.677 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 827 from chain A and a score of 0.662 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 610 from chain A and a score of 0.654 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 724 from chain A and a score of 0.648 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 458 from chain A and a score of 0.585 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 305 from chain A and a score of 0.527 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 666 from chain A and a score of 0.515 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 511 from chain A and a score of 0.476 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 304 from chain A and a score of 0.416 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 828 from chain A and a score of 0.415 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 26 from chain A and a score of 0.349 (proline) selected for
automated muatation (00:06:15)
[INFO] Auto_mut: Residue number 676 from chain A and a score of 0.321 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 311 from chain A and a score of 0.310 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 459 from chain A and a score of 0.304 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 837 from chain A and a score of 0.302 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 652 from chain A and a score of 0.287 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 369 from chain A and a score of 0.284 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 484 from chain A and a score of 0.281 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 653 from chain A and a score of 0.280 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 253 from chain A and a score of 0.264 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 288 from chain A and a score of 0.253 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 68 from chain A and a score of 0.253 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 368 from chain A and a score of 0.253 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 281 from chain A and a score of 0.246 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 833 from chain A and a score of 0.232 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 252 from chain A and a score of 0.188 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 287 from chain A and a score of 0.177 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 365 from chain A and a score of 0.153 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 375 from chain A and a score of 0.152 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 261 from chain A and a score of 0.138 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 460 from chain A and a score of 0.132 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 170 from chain A and a score of 0.129 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 457 from chain A and a score of 0.128 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 479 from chain A and a score of 0.127 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 123 from chain A and a score of 0.116 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 282 from chain A and a score of 0.114 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 829 from chain A and a score of 0.114 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 429 from chain A and a score of 0.100 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 512 from chain A and a score of 0.097 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 28 from chain A and a score of 0.092 (phenylalanine)
selected for automated muatation (00:06:15)
[INFO] Auto_mut: Residue number 814 from chain A and a score of 0.090 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 69 from chain A and a score of 0.090 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 382 from chain A and a score of 0.075 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 102 from chain A and a score of 0.062 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 269 from chain A and a score of 0.059 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 265 from chain A and a score of 0.042 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 832 from chain A and a score of 0.014 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 286 from chain A and a score of 0.012 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 34 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 40 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 43 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 47 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 51 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 54 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 56 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 59 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 60 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 62 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 63 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 64 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 65 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 66 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 67 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 70 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 73 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 74 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 75 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 76 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 77 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 79 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 80 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 85 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 88 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 89 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 90 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 91 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 92 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 93 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 94 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 95 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 96 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 97 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 100 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 103 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 104 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 105 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 106 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 107 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 108 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 109 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 110 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 111 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 112 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 113 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 114 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 115 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 116 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 120 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 121 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 124 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 125 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 127 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 128 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 129 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 131 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 132 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 135 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 136 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 137 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 138 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 139 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 140 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 141 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 142 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 143 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 144 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 145 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 146 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 147 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 148 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 150 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 151 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 153 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 154 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 155 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 156 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 157 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 158 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 159 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 160 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 161 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 162 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 163 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 164 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 165 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 166 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 167 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 168 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 169 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 171 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 172 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 175 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 176 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 178 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 179 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 183 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 184 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 185 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 186 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 187 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 188 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 189 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 190 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 191 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 192 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 193 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 194 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 195 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 196 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 197 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 199 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 200 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 205 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 212 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 215 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 216 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 217 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 218 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 224 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 225 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 226 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 228 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 229 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 230 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 231 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 232 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 233 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 234 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 236 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 237 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 240 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 241 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 242 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 243 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 244 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 245 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 246 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 247 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 248 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 249 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 250 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 251 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 255 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 256 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 257 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 259 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 260 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 262 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 263 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 264 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 266 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 267 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 268 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 270 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 271 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 273 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 274 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 275 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 276 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 277 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 278 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 279 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 280 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 283 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 284 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 290 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 291 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 292 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 293 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 294 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 295 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 296 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 297 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 298 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 299 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 300 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 301 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 302 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 310 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 312 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 313 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 316 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 317 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 318 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 319 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 320 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 325 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 328 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 329 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 330 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 331 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 332 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 333 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 334 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 335 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 336 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 337 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 338 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 339 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 340 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 341 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 345 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 346 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 353 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 355 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 356 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 357 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 378 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 379 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 384 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 388 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 392 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 395 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 396 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 397 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 398 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 399 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 400 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 401 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 402 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 403 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 409 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 411 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 413 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 418 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 419 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 420 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 421 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 422 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 424 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 425 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 426 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 438 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 441 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 443 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 444 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 445 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 446 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 447 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 448 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 449 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 450 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 452 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 453 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 454 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 456 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 461 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 462 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 465 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 466 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 470 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 483 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 489 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 492 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 493 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 498 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 499 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 500 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 501 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 502 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 503 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 504 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 505 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 506 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 507 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 508 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 509 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 510 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 517 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 519 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 520 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 521 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 524 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 526 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 530 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 533 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 534 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 536 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 537 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 538 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 541 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 544 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 545 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 546 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 547 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 548 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 549 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 550 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 551 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 552 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 553 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 554 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 556 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 559 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 565 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 567 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 568 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 569 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 570 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 571 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 572 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 573 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 574 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 575 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 576 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 577 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 578 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 579 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 581 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 582 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 583 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 584 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 585 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 586 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 592 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 593 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 594 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 596 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 597 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 598 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 599 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 600 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 601 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 606 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 607 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 609 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 611 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 621 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 622 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 624 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 626 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 630 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 631 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 632 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 633 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 634 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 635 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 636 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 637 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 638 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 644 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 646 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 648 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 649 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 655 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 659 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 694 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 707 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 709 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 711 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 737 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 748 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 749 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 751 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 753 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 754 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 758 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 762 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 763 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 765 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 767 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 769 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 771 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 777 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 779 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 780 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 781 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 782 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 783 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 784 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 785 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 787 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 793 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 796 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 797 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 798 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 800 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 805 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 813 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 817 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 820 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 821 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 822 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 823 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 824 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 825 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 839 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 841 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 843 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 844 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 846 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 847 from chain A and a score of 0.000 omitted from automated
muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 202 from chain A and a score of -0.023 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 477 from chain A and a score of -0.027 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 826 from chain A and a score of -0.036 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 651 from chain A and a score of -0.042 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 254 from chain A and a score of -0.048 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 431 from chain A and a score of -0.049 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 309 from chain A and a score of -0.054 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 201 from chain A and a score of -0.056 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 149 from chain A and a score of -0.056 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 830 from chain A and a score of -0.062 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 835 from chain A and a score of -0.073 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 307 from chain A and a score of -0.077 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 152 from chain A and a score of -0.084 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 747 from chain A and a score of -0.090 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 381 from chain A and a score of -0.096 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 654 from chain A and a score of -0.099 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 451 from chain A and a score of -0.114 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 708 from chain A and a score of -0.114 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 203 from chain A and a score of -0.123 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 27 from chain A and a score of -0.134 (proline) selected for
automated muatation (00:06:15)
[INFO] Auto_mut: Residue number 834 from chain A and a score of -0.139 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 750 from chain A and a score of -0.142 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 289 from chain A and a score of -0.144 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 836 from chain A and a score of -0.151 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 314 from chain A and a score of -0.156 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 595 from chain A and a score of -0.162 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 308 from chain A and a score of -0.167 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 480 from chain A and a score of -0.169 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 306 from chain A and a score of -0.177 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 803 from chain A and a score of -0.179 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Residue number 285 from chain A and a score of -0.189 omitted from
automated muatation (excluded by the user). (00:06:15)
[INFO] Auto_mut: Mutating residue number 24 from chain A (phenylalanine) into arginine (00:06:15)
[INFO] Auto_mut: Mutating residue number 22 from chain A (leucine) into aspartic acid (00:06:15)
[INFO] Auto_mut: Mutating residue number 24 from chain A (phenylalanine) into glutamic acid
Mutating residue number 24 from chain A (phenylalanine) into glutamic acid (00:06:15)
[INFO] Auto_mut: Mutating residue number 22 from chain A (leucine) into arginine (00:09:33)
[INFO] Auto_mut: Mutating residue number 24 from chain A (phenylalanine) into lysine (00:09:38)
[INFO] Auto_mut: Mutating residue number 22 from chain A (leucine) into glutamic acid (00:09:54)
[INFO] Auto_mut: Mutating residue number 24 from chain A (phenylalanine) into aspartic acid
Mutating residue number 24 from chain A (phenylalanine) into aspartic acid (00:13:03)
[INFO] Auto_mut: Mutating residue number 23 from chain A (alanine) into glutamic acid (00:13:06)
[INFO] Auto_mut: Mutating residue number 22 from chain A (leucine) into lysine (00:13:16)
[INFO] Auto_mut: Mutating residue number 23 from chain A (alanine) into lysine (00:16:22)
[INFO] Auto_mut: Mutating residue number 25 from chain A (serine) into glutamic acid (00:16:37)
[INFO] Auto_mut: Mutating residue number 25 from chain A (serine) into arginine (00:16:43)
[INFO] Auto_mut: Mutating residue number 23 from chain A (alanine) into aspartic acid (00:19:46)
[INFO] Auto_mut: Mutating residue number 26 from chain A (proline) into glutamic acid (00:20:06)
[INFO] Auto_mut: Mutating residue number 25 from chain A (serine) into lysine (00:20:09)
[INFO] Auto_mut: Mutating residue number 23 from chain A (alanine) into arginine (00:23:06)
[INFO] Auto_mut: Mutating residue number 26 from chain A (proline) into lysine (00:23:29)
[INFO] Auto_mut: Mutating residue number 25 from chain A (serine) into aspartic acid (00:23:44)
[INFO] Auto_mut: Mutating residue number 26 from chain A (proline) into aspartic acid (00:26:27)
[INFO] Auto_mut: Mutating residue number 28 from chain A (phenylalanine) into lysine (00:27:01)
[INFO] Auto_mut: Mutating residue number 27 from chain A (proline) into glutamic acid (00:27:01)
[INFO] Auto_mut: Mutating residue number 26 from chain A (proline) into arginine (00:29:41)
[INFO] Auto_mut: Mutating residue number 27 from chain A (proline) into lysine (00:30:12)
[INFO] Auto_mut: Mutating residue number 28 from chain A (phenylalanine) into aspartic acid
Mutating residue number 28 from chain A (phenylalanine) into aspartic acid (00:30:49)
[INFO] Auto_mut: Mutating residue number 28 from chain A (phenylalanine) into glutamic acid
Mutating residue number 28 from chain A (phenylalanine) into glutamic acid (00:33:11)
[INFO] Auto_mut: Mutating residue number 27 from chain A (proline) into aspartic acid (00:33:58)
[INFO] Auto_mut: Mutating residue number 28 from chain A (phenylalanine) into arginine (00:34:21)
[INFO] Auto_mut: Mutating residue number 27 from chain A (proline) into arginine (00:36:50)
[INFO] Auto_mut: Effect of mutation residue number 24 from chain A (phenylalanine) into
glutamic acid: Energy difference: 0.6581 kcal/mol, Difference in average
score from the base case: -0.0149 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 24 from chain A (phenylalanine) into
lysine: Energy difference: 0.5746 kcal/mol, Difference in average score
from the base case: -0.0148 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 24 from chain A (phenylalanine) into
aspartic acid: Energy difference: 1.2307 kcal/mol, Difference in average
score from the base case: -0.0146 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 24 from chain A (phenylalanine) into
arginine: Energy difference: 0.6512 kcal/mol, Difference in average score
from the base case: -0.0147 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 22 from chain A (leucine) into glutamic
acid: Energy difference: 0.5856 kcal/mol, Difference in average score from
the base case: -0.0086 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 22 from chain A (leucine) into lysine:
Energy difference: 0.3835 kcal/mol, Difference in average score from the
base case: -0.0079 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 22 from chain A (leucine) into aspartic
acid: Energy difference: 0.6410 kcal/mol, Difference in average score from
the base case: -0.0089 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 22 from chain A (leucine) into arginine:
Energy difference: -0.1605 kcal/mol, Difference in average score from the
base case: -0.0080 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 23 from chain A (alanine) into glutamic
acid: Energy difference: 0.8913 kcal/mol, Difference in average score from
the base case: -0.0007 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 23 from chain A (alanine) into lysine:
Energy difference: -0.2730 kcal/mol, Difference in average score from the
base case: -0.0002 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 23 from chain A (alanine) into aspartic
acid: Energy difference: 1.1924 kcal/mol, Difference in average score from
the base case: 0.0003 (00:40:14)
[INFO] Auto_mut: Effect of mutation residue number 23 from chain A (alanine) into arginine:
Energy difference: 0.6183 kcal/mol, Difference in average score from the
base case: -0.0026 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 25 from chain A (serine) into glutamic
acid: Energy difference: -0.1722 kcal/mol, Difference in average score from
the base case: 0.0010 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 25 from chain A (serine) into lysine:
Energy difference: 0.6307 kcal/mol, Difference in average score from the
base case: -0.0001 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 25 from chain A (serine) into aspartic
acid: Energy difference: 1.4853 kcal/mol, Difference in average score from
the base case: 0.0016 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 25 from chain A (serine) into arginine:
Energy difference: -0.0849 kcal/mol, Difference in average score from the
base case: 0.0003 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 26 from chain A (proline) into glutamic
acid: Energy difference: 1.2567 kcal/mol, Difference in average score from
the base case: -0.0035 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 26 from chain A (proline) into lysine:
Energy difference: 1.3815 kcal/mol, Difference in average score from the
base case: -0.0048 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 26 from chain A (proline) into aspartic
acid: Energy difference: 1.3776 kcal/mol, Difference in average score from
the base case: -0.0041 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 26 from chain A (proline) into arginine:
Energy difference: 0.3198 kcal/mol, Difference in average score from the
base case: 0.0003 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 28 from chain A (phenylalanine) into
glutamic acid: Energy difference: 1.7755 kcal/mol, Difference in average
score from the base case: -0.0018 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 28 from chain A (phenylalanine) into
lysine: Energy difference: 1.3322 kcal/mol, Difference in average score
from the base case: -0.0032 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 28 from chain A (phenylalanine) into
aspartic acid: Energy difference: 2.8151 kcal/mol, Difference in average
score from the base case: -0.0009 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 28 from chain A (phenylalanine) into
arginine: Energy difference: 1.3359 kcal/mol, Difference in average score
from the base case: -0.0057 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 27 from chain A (proline) into glutamic
acid: Energy difference: 0.5011 kcal/mol, Difference in average score from
the base case: -0.0040 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 27 from chain A (proline) into lysine:
Energy difference: 0.7372 kcal/mol, Difference in average score from the
base case: -0.0043 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 27 from chain A (proline) into aspartic
acid: Energy difference: 1.1122 kcal/mol, Difference in average score from
the base case: -0.0034 (00:40:15)
[INFO] Auto_mut: Effect of mutation residue number 27 from chain A (proline) into arginine:
Energy difference: 0.6845 kcal/mol, Difference in average score from the
base case: -0.0052 (00:40:15)
[INFO] Main: Simulation completed successfully. (00:40:33)
|
The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.
| residue index | residue name | chain | Aggrescan3D score | mutation |
|---|---|---|---|---|
| residue index | residue name | chain | Aggrescan3D score | |
| 22 | L | A | 1.8703 | |
| 23 | A | A | 1.2923 | |
| 24 | F | A | 2.0835 | |
| 25 | S | A | 0.8664 | |
| 26 | P | A | 0.3494 | |
| 27 | P | A | -0.1341 | |
| 28 | F | A | 0.0922 | |
| 29 | Y | A | -0.2642 | |
| 30 | P | A | 0.0000 | |
| 31 | S | A | 0.0000 | |
| 32 | P | A | -0.2068 | |
| 33 | W | A | 0.0000 | |
| 34 | A | A | 0.0000 | |
| 35 | N | A | -1.6447 | |
| 36 | G | A | -1.5867 | |
| 37 | Q | A | -1.3542 | |
| 38 | G | A | -1.5123 | |
| 39 | E | A | -1.6797 | |
| 40 | W | A | 0.0000 | |
| 41 | A | A | -2.0494 | |
| 42 | E | A | -2.8209 | |
| 43 | A | A | 0.0000 | |
| 44 | Y | A | -1.7761 | |
| 45 | Q | A | -2.3429 | |
| 46 | R | A | -2.1200 | |
| 47 | A | A | 0.0000 | |
| 48 | V | A | -0.5910 | |
| 49 | A | A | -0.7013 | |
| 50 | I | A | -0.4708 | |
| 51 | V | A | 0.0000 | |
| 52 | S | A | -0.7915 | |
| 53 | Q | A | -1.1831 | |
| 54 | M | A | 0.0000 | |
| 55 | T | A | -0.8427 | |
| 56 | L | A | 0.0000 | |
| 57 | D | A | -0.4264 | |
| 58 | E | A | -0.7525 | |
| 59 | K | A | 0.0000 | |
| 60 | V | A | 0.0000 | |
| 61 | N | A | -0.3405 | |
| 62 | L | A | 0.0000 | |
| 63 | T | A | 0.0000 | |
| 64 | T | A | 0.0000 | |
| 65 | G | A | 0.0000 | |
| 66 | T | A | 0.0000 | |
| 67 | G | A | 0.0000 | |
| 68 | W | A | 0.2528 | |
| 69 | E | A | 0.0898 | |
| 70 | L | A | 0.0000 | |
| 71 | E | A | -0.2098 | |
| 72 | K | A | -0.4345 | |
| 73 | C | A | 0.0000 | |
| 74 | V | A | 0.0000 | |
| 75 | G | A | 0.0000 | |
| 76 | Q | A | 0.0000 | |
| 77 | T | A | 0.0000 | |
| 78 | G | A | -0.3219 | |
| 79 | G | A | 0.0000 | |
| 80 | V | A | 0.0000 | |
| 81 | P | A | -1.6468 | |
| 82 | R | A | -2.2812 | |
| 83 | L | A | -1.5197 | |
| 84 | N | A | -1.9100 | |
| 85 | I | A | 0.0000 | |
| 86 | G | A | -1.0169 | |
| 87 | G | A | -0.5981 | |
| 88 | M | A | 0.0000 | |
| 89 | C | A | 0.0000 | |
| 90 | L | A | 0.0000 | |
| 91 | Q | A | 0.0000 | |
| 92 | D | A | 0.0000 | |
| 93 | S | A | 0.0000 | |
| 94 | P | A | 0.0000 | |
| 95 | L | A | 0.0000 | |
| 96 | G | A | 0.0000 | |
| 97 | I | A | 0.0000 | |
| 98 | R | A | -0.5479 | |
| 99 | D | A | -0.7246 | |
| 100 | S | A | 0.0000 | |
| 101 | D | A | -0.4935 | |
| 102 | Y | A | 0.0624 | |
| 103 | N | A | 0.0000 | |
| 104 | S | A | 0.0000 | |
| 105 | A | A | 0.0000 | |
| 106 | F | A | 0.0000 | |
| 107 | P | A | 0.0000 | |
| 108 | A | A | 0.0000 | |
| 109 | G | A | 0.0000 | |
| 110 | V | A | 0.0000 | |
| 111 | N | A | 0.0000 | |
| 112 | V | A | 0.0000 | |
| 113 | A | A | 0.0000 | |
| 114 | A | A | 0.0000 | |
| 115 | T | A | 0.0000 | |
| 116 | W | A | 0.0000 | |
| 117 | D | A | -0.9565 | |
| 118 | K | A | -1.1646 | |
| 119 | N | A | -1.4556 | |
| 120 | L | A | 0.0000 | |
| 121 | A | A | 0.0000 | |
| 122 | Y | A | -0.7219 | |
| 123 | L | A | 0.1159 | |
| 124 | R | A | 0.0000 | |
| 125 | G | A | 0.0000 | |
| 126 | Q | A | -0.7973 | |
| 127 | A | A | 0.0000 | |
| 128 | M | A | 0.0000 | |
| 129 | G | A | 0.0000 | |
| 130 | Q | A | -1.0543 | |
| 131 | E | A | 0.0000 | |
| 132 | F | A | 0.0000 | |
| 133 | S | A | -0.3788 | |
| 134 | D | A | -0.8524 | |
| 135 | K | A | 0.0000 | |
| 136 | G | A | 0.0000 | |
| 137 | I | A | 0.0000 | |
| 138 | D | A | 0.0000 | |
| 139 | V | A | 0.0000 | |
| 140 | Q | A | 0.0000 | |
| 141 | L | A | 0.0000 | |
| 142 | G | A | 0.0000 | |
| 143 | P | A | 0.0000 | |
| 144 | A | A | 0.0000 | |
| 145 | A | A | 0.0000 | |
| 146 | G | A | 0.0000 | |
| 147 | P | A | 0.0000 | |
| 148 | L | A | 0.0000 | |
| 149 | G | A | -0.0563 | |
| 150 | R | A | 0.0000 | |
| 151 | S | A | 0.0000 | |
| 152 | P | A | -0.0841 | |
| 153 | D | A | 0.0000 | |
| 154 | G | A | 0.0000 | |
| 155 | G | A | 0.0000 | |
| 156 | R | A | 0.0000 | |
| 157 | N | A | 0.0000 | |
| 158 | W | A | 0.0000 | |
| 159 | E | A | 0.0000 | |
| 160 | G | A | 0.0000 | |
| 161 | F | A | 0.0000 | |
| 162 | S | A | 0.0000 | |
| 163 | P | A | 0.0000 | |
| 164 | D | A | 0.0000 | |
| 165 | P | A | 0.0000 | |
| 166 | A | A | 0.0000 | |
| 167 | L | A | 0.0000 | |
| 168 | T | A | 0.0000 | |
| 169 | G | A | 0.0000 | |
| 170 | V | A | 0.1289 | |
| 171 | L | A | 0.0000 | |
| 172 | F | A | 0.0000 | |
| 173 | A | A | -0.5099 | |
| 174 | E | A | -0.8738 | |
| 175 | T | A | 0.0000 | |
| 176 | I | A | 0.0000 | |
| 177 | K | A | -1.6151 | |
| 178 | G | A | 0.0000 | |
| 179 | I | A | 0.0000 | |
| 180 | Q | A | -1.4599 | |
| 181 | D | A | -2.2642 | |
| 182 | A | A | -1.1425 | |
| 183 | G | A | 0.0000 | |
| 184 | V | A | 0.0000 | |
| 185 | V | A | 0.0000 | |
| 186 | A | A | 0.0000 | |
| 187 | T | A | 0.0000 | |
| 188 | A | A | 0.0000 | |
| 189 | K | A | 0.0000 | |
| 190 | H | A | 0.0000 | |
| 191 | Y | A | 0.0000 | |
| 192 | I | A | 0.0000 | |
| 193 | L | A | 0.0000 | |
| 194 | N | A | 0.0000 | |
| 195 | E | A | 0.0000 | |
| 196 | Q | A | 0.0000 | |
| 197 | E | A | 0.0000 | |
| 198 | H | A | -0.3527 | |
| 199 | F | A | 0.0000 | |
| 200 | R | A | 0.0000 | |
| 201 | Q | A | -0.0556 | |
| 202 | V | A | -0.0226 | |
| 203 | A | A | -0.1228 | |
| 204 | E | A | -0.2239 | |
| 205 | A | A | 0.0000 | |
| 206 | A | A | -0.4688 | |
| 207 | G | A | -0.4373 | |
| 208 | Y | A | -0.2488 | |
| 209 | G | A | -0.5883 | |
| 210 | F | A | -0.8600 | |
| 211 | N | A | -1.6537 | |
| 212 | I | A | 0.0000 | |
| 213 | S | A | -1.0691 | |
| 214 | D | A | -0.9989 | |
| 215 | T | A | 0.0000 | |
| 216 | I | A | 0.0000 | |
| 217 | S | A | 0.0000 | |
| 218 | S | A | 0.0000 | |
| 219 | N | A | -0.7841 | |
| 220 | V | A | -1.2829 | |
| 221 | D | A | -1.8162 | |
| 222 | D | A | -1.0048 | |
| 223 | K | A | -0.8653 | |
| 224 | T | A | 0.0000 | |
| 225 | I | A | 0.0000 | |
| 226 | H | A | 0.0000 | |
| 227 | E | A | -0.3418 | |
| 228 | M | A | 0.0000 | |
| 229 | Y | A | 0.0000 | |
| 230 | L | A | 0.0000 | |
| 231 | W | A | 0.0000 | |
| 232 | P | A | 0.0000 | |
| 233 | F | A | 0.0000 | |
| 234 | A | A | 0.0000 | |
| 235 | D | A | -0.4514 | |
| 236 | A | A | 0.0000 | |
| 237 | V | A | 0.0000 | |
| 238 | R | A | -1.1079 | |
| 239 | A | A | -0.8330 | |
| 240 | G | A | 0.0000 | |
| 241 | V | A | 0.0000 | |
| 242 | G | A | 0.0000 | |
| 243 | A | A | 0.0000 | |
| 244 | I | A | 0.0000 | |
| 245 | M | A | 0.0000 | |
| 246 | C | A | 0.0000 | |
| 247 | S | A | 0.0000 | |
| 248 | Y | A | 0.0000 | |
| 249 | N | A | 0.0000 | |
| 250 | Q | A | 0.0000 | |
| 251 | I | A | 0.0000 | |
| 252 | N | A | 0.1881 | |
| 253 | N | A | 0.2640 | |
| 254 | S | A | -0.0479 | |
| 255 | Y | A | 0.0000 | |
| 256 | G | A | 0.0000 | |
| 257 | C | A | 0.0000 | |
| 258 | Q | A | -0.3185 | |
| 259 | N | A | 0.0000 | |
| 260 | S | A | 0.0000 | |
| 261 | Y | A | 0.1377 | |
| 262 | T | A | 0.0000 | |
| 263 | L | A | 0.0000 | |
| 264 | N | A | 0.0000 | |
| 265 | K | A | 0.0423 | |
| 266 | L | A | 0.0000 | |
| 267 | L | A | 0.0000 | |
| 268 | K | A | 0.0000 | |
| 269 | A | A | 0.0588 | |
| 270 | E | A | 0.0000 | |
| 271 | L | A | 0.0000 | |
| 272 | G | A | -0.4478 | |
| 273 | F | A | 0.0000 | |
| 274 | Q | A | 0.0000 | |
| 275 | G | A | 0.0000 | |
| 276 | F | A | 0.0000 | |
| 277 | V | A | 0.0000 | |
| 278 | M | A | 0.0000 | |
| 279 | S | A | 0.0000 | |
| 280 | D | A | 0.0000 | |
| 281 | W | A | 0.2465 | |
| 282 | G | A | 0.1141 | |
| 283 | A | A | 0.0000 | |
| 284 | H | A | 0.0000 | |
| 285 | H | A | -0.1887 | |
| 286 | S | A | 0.0121 | |
| 287 | G | A | 0.1773 | |
| 288 | V | A | 0.2534 | |
| 289 | G | A | -0.1437 | |
| 290 | S | A | 0.0000 | |
| 291 | A | A | 0.0000 | |
| 292 | L | A | 0.0000 | |
| 293 | A | A | 0.0000 | |
| 294 | G | A | 0.0000 | |
| 295 | L | A | 0.0000 | |
| 296 | D | A | 0.0000 | |
| 297 | M | A | 0.0000 | |
| 298 | S | A | 0.0000 | |
| 299 | M | A | 0.0000 | |
| 300 | P | A | 0.0000 | |
| 301 | G | A | 0.0000 | |
| 302 | D | A | 0.0000 | |
| 303 | I | A | 0.6771 | |
| 304 | T | A | 0.4162 | |
| 305 | F | A | 0.5270 | |
| 306 | D | A | -0.1769 | |
| 307 | S | A | -0.0771 | |
| 308 | A | A | -0.1673 | |
| 309 | T | A | -0.0538 | |
| 310 | S | A | 0.0000 | |
| 311 | F | A | 0.3096 | |
| 312 | W | A | 0.0000 | |
| 313 | G | A | 0.0000 | |
| 314 | T | A | -0.1557 | |
| 315 | N | A | -0.3472 | |
| 316 | L | A | 0.0000 | |
| 317 | T | A | 0.0000 | |
| 318 | I | A | 0.0000 | |
| 319 | A | A | 0.0000 | |
| 320 | V | A | 0.0000 | |
| 321 | L | A | -0.3894 | |
| 322 | N | A | -0.9369 | |
| 323 | G | A | -0.7471 | |
| 324 | T | A | -0.3232 | |
| 325 | V | A | 0.0000 | |
| 326 | P | A | -0.4427 | |
| 327 | Q | A | -0.3765 | |
| 328 | W | A | 0.0000 | |
| 329 | R | A | 0.0000 | |
| 330 | V | A | 0.0000 | |
| 331 | D | A | 0.0000 | |
| 332 | D | A | 0.0000 | |
| 333 | M | A | 0.0000 | |
| 334 | A | A | 0.0000 | |
| 335 | V | A | 0.0000 | |
| 336 | R | A | 0.0000 | |
| 337 | I | A | 0.0000 | |
| 338 | M | A | 0.0000 | |
| 339 | A | A | 0.0000 | |
| 340 | A | A | 0.0000 | |
| 341 | Y | A | 0.0000 | |
| 342 | Y | A | -1.1028 | |
| 343 | K | A | -1.3312 | |
| 344 | V | A | -0.8509 | |
| 345 | G | A | 0.0000 | |
| 346 | R | A | 0.0000 | |
| 347 | D | A | -1.2901 | |
| 348 | R | A | -1.6481 | |
| 349 | L | A | -0.3432 | |
| 350 | Y | A | -0.7261 | |
| 351 | Q | A | -1.4179 | |
| 352 | P | A | -0.8986 | |
| 353 | P | A | 0.0000 | |
| 354 | N | A | -0.6739 | |
| 355 | F | A | 0.0000 | |
| 356 | S | A | 0.0000 | |
| 357 | S | A | 0.0000 | |
| 358 | W | A | -0.2058 | |
| 359 | T | A | -0.9389 | |
| 360 | R | A | -1.8645 | |
| 361 | D | A | -2.6902 | |
| 362 | E | A | -2.6680 | |
| 363 | Y | A | -1.2918 | |
| 364 | G | A | -0.7672 | |
| 365 | F | A | 0.1533 | |
| 366 | K | A | -0.9618 | |
| 367 | Y | A | -0.2214 | |
| 368 | F | A | 0.2528 | |
| 369 | Y | A | 0.2836 | |
| 370 | P | A | -0.3916 | |
| 371 | Q | A | -0.6436 | |
| 372 | E | A | -0.6544 | |
| 373 | G | A | -0.8251 | |
| 374 | P | A | -0.5856 | |
| 375 | Y | A | 0.1521 | |
| 376 | E | A | -1.6620 | |
| 377 | K | A | -2.0487 | |
| 378 | V | A | 0.0000 | |
| 379 | N | A | 0.0000 | |
| 380 | H | A | -1.0938 | |
| 381 | F | A | -0.0957 | |
| 382 | V | A | 0.0750 | |
| 383 | N | A | -1.1529 | |
| 384 | V | A | 0.0000 | |
| 385 | Q | A | -1.7050 | |
| 386 | R | A | -2.9413 | |
| 387 | N | A | -2.6835 | |
| 388 | H | A | 0.0000 | |
| 389 | S | A | -1.9335 | |
| 390 | E | A | -2.7790 | |
| 391 | V | A | -1.3204 | |
| 392 | I | A | 0.0000 | |
| 393 | R | A | -1.7620 | |
| 394 | K | A | -1.7882 | |
| 395 | L | A | 0.0000 | |
| 396 | G | A | 0.0000 | |
| 397 | A | A | 0.0000 | |
| 398 | D | A | 0.0000 | |
| 399 | S | A | 0.0000 | |
| 400 | T | A | 0.0000 | |
| 401 | V | A | 0.0000 | |
| 402 | L | A | 0.0000 | |
| 403 | L | A | 0.0000 | |
| 404 | K | A | -0.9853 | |
| 405 | N | A | -1.3533 | |
| 406 | N | A | -2.1818 | |
| 407 | N | A | -2.0205 | |
| 408 | A | A | -1.2330 | |
| 409 | L | A | 0.0000 | |
| 410 | P | A | -0.5889 | |
| 411 | L | A | 0.0000 | |
| 412 | T | A | -0.7471 | |
| 413 | G | A | 0.0000 | |
| 414 | K | A | -2.7194 | |
| 415 | E | A | -2.3221 | |
| 416 | R | A | -3.0601 | |
| 417 | K | A | -1.8548 | |
| 418 | V | A | 0.0000 | |
| 419 | A | A | 0.0000 | |
| 420 | I | A | 0.0000 | |
| 421 | L | A | 0.0000 | |
| 422 | G | A | 0.0000 | |
| 423 | E | A | -0.9001 | |
| 424 | D | A | 0.0000 | |
| 425 | A | A | 0.0000 | |
| 426 | G | A | 0.0000 | |
| 427 | S | A | -0.4213 | |
| 428 | N | A | -0.2713 | |
| 429 | S | A | 0.0996 | |
| 430 | Y | A | 0.7146 | |
| 431 | G | A | -0.0493 | |
| 432 | A | A | -0.2425 | |
| 433 | N | A | -0.7628 | |
| 434 | G | A | -0.4263 | |
| 435 | C | A | -0.3282 | |
| 436 | S | A | -0.6526 | |
| 437 | D | A | -0.7268 | |
| 438 | R | A | 0.0000 | |
| 439 | G | A | -0.2361 | |
| 440 | C | A | -0.3578 | |
| 441 | D | A | 0.0000 | |
| 442 | N | A | -0.3906 | |
| 443 | G | A | 0.0000 | |
| 444 | T | A | 0.0000 | |
| 445 | L | A | 0.0000 | |
| 446 | A | A | 0.0000 | |
| 447 | M | A | 0.0000 | |
| 448 | A | A | 0.0000 | |
| 449 | W | A | 0.0000 | |
| 450 | G | A | 0.0000 | |
| 451 | S | A | -0.1135 | |
| 452 | G | A | 0.0000 | |
| 453 | T | A | 0.0000 | |
| 454 | A | A | 0.0000 | |
| 455 | E | A | -0.7201 | |
| 456 | F | A | 0.0000 | |
| 457 | P | A | 0.1279 | |
| 458 | Y | A | 0.5853 | |
| 459 | L | A | 0.3043 | |
| 460 | V | A | 0.1324 | |
| 461 | T | A | 0.0000 | |
| 462 | P | A | 0.0000 | |
| 463 | E | A | -0.8770 | |
| 464 | Q | A | -1.2404 | |
| 465 | A | A | 0.0000 | |
| 466 | I | A | 0.0000 | |
| 467 | Q | A | -0.7802 | |
| 468 | A | A | -0.9335 | |
| 469 | E | A | -1.0235 | |
| 470 | V | A | 0.0000 | |
| 471 | L | A | -0.6976 | |
| 472 | K | A | -1.9538 | |
| 473 | H | A | -2.2233 | |
| 474 | K | A | -2.5450 | |
| 475 | G | A | -2.1604 | |
| 476 | S | A | -0.7818 | |
| 477 | V | A | -0.0273 | |
| 478 | Y | A | 0.9134 | |
| 479 | A | A | 0.1266 | |
| 480 | I | A | -0.1687 | |
| 481 | T | A | -0.7155 | |
| 482 | D | A | -1.5953 | |
| 483 | N | A | 0.0000 | |
| 484 | W | A | 0.2805 | |
| 485 | A | A | -0.3125 | |
| 486 | L | A | -0.4699 | |
| 487 | S | A | -0.6911 | |
| 488 | Q | A | -1.4451 | |
| 489 | V | A | 0.0000 | |
| 490 | E | A | -2.0357 | |
| 491 | T | A | -1.6588 | |
| 492 | L | A | 0.0000 | |
| 493 | A | A | 0.0000 | |
| 494 | K | A | -2.9236 | |
| 495 | Q | A | -2.4458 | |
| 496 | A | A | -1.7401 | |
| 497 | S | A | -1.7327 | |
| 498 | V | A | 0.0000 | |
| 499 | S | A | 0.0000 | |
| 500 | L | A | 0.0000 | |
| 501 | V | A | 0.0000 | |
| 502 | F | A | 0.0000 | |
| 503 | V | A | 0.0000 | |
| 504 | N | A | 0.0000 | |
| 505 | S | A | 0.0000 | |
| 506 | D | A | 0.0000 | |
| 507 | A | A | 0.0000 | |
| 508 | G | A | 0.0000 | |
| 509 | E | A | 0.0000 | |
| 510 | G | A | 0.0000 | |
| 511 | Y | A | 0.4763 | |
| 512 | I | A | 0.0968 | |
| 513 | S | A | -0.4322 | |
| 514 | V | A | -0.8745 | |
| 515 | D | A | -2.0512 | |
| 516 | G | A | -1.4940 | |
| 517 | N | A | 0.0000 | |
| 518 | E | A | -0.6918 | |
| 519 | G | A | 0.0000 | |
| 520 | D | A | 0.0000 | |
| 521 | R | A | 0.0000 | |
| 522 | N | A | -1.9043 | |
| 523 | N | A | -1.5987 | |
| 524 | L | A | 0.0000 | |
| 525 | T | A | -0.5318 | |
| 526 | L | A | 0.0000 | |
| 527 | W | A | -0.4845 | |
| 528 | K | A | -0.7455 | |
| 529 | N | A | -0.8314 | |
| 530 | G | A | 0.0000 | |
| 531 | D | A | -1.6941 | |
| 532 | N | A | -1.7709 | |
| 533 | L | A | 0.0000 | |
| 534 | I | A | 0.0000 | |
| 535 | K | A | -1.9289 | |
| 536 | A | A | 0.0000 | |
| 537 | A | A | 0.0000 | |
| 538 | A | A | 0.0000 | |
| 539 | N | A | -2.2332 | |
| 540 | N | A | -2.2683 | |
| 541 | C | A | 0.0000 | |
| 542 | N | A | -2.0556 | |
| 543 | N | A | -1.1744 | |
| 544 | T | A | 0.0000 | |
| 545 | I | A | 0.0000 | |
| 546 | V | A | 0.0000 | |
| 547 | V | A | 0.0000 | |
| 548 | I | A | 0.0000 | |
| 549 | H | A | 0.0000 | |
| 550 | S | A | 0.0000 | |
| 551 | V | A | 0.0000 | |
| 552 | G | A | 0.0000 | |
| 553 | P | A | 0.0000 | |
| 554 | V | A | 0.0000 | |
| 555 | L | A | -0.8250 | |
| 556 | V | A | 0.0000 | |
| 557 | D | A | -2.7572 | |
| 558 | E | A | -3.1429 | |
| 559 | W | A | 0.0000 | |
| 560 | Y | A | -1.6397 | |
| 561 | D | A | -2.4317 | |
| 562 | H | A | -1.9866 | |
| 563 | P | A | -1.4101 | |
| 564 | N | A | -1.6875 | |
| 565 | V | A | 0.0000 | |
| 566 | T | A | -1.4607 | |
| 567 | A | A | 0.0000 | |
| 568 | I | A | 0.0000 | |
| 569 | L | A | 0.0000 | |
| 570 | W | A | 0.0000 | |
| 571 | A | A | 0.0000 | |
| 572 | G | A | 0.0000 | |
| 573 | L | A | 0.0000 | |
| 574 | P | A | 0.0000 | |
| 575 | G | A | 0.0000 | |
| 576 | Q | A | 0.0000 | |
| 577 | E | A | 0.0000 | |
| 578 | S | A | 0.0000 | |
| 579 | G | A | 0.0000 | |
| 580 | N | A | -0.6538 | |
| 581 | S | A | 0.0000 | |
| 582 | L | A | 0.0000 | |
| 583 | A | A | 0.0000 | |
| 584 | D | A | 0.0000 | |
| 585 | V | A | 0.0000 | |
| 586 | L | A | 0.0000 | |
| 587 | Y | A | -0.4679 | |
| 588 | G | A | -0.7600 | |
| 589 | R | A | -1.4859 | |
| 590 | V | A | -0.8015 | |
| 591 | N | A | -0.2426 | |
| 592 | P | A | 0.0000 | |
| 593 | G | A | 0.0000 | |
| 594 | A | A | 0.0000 | |
| 595 | K | A | -0.1617 | |
| 596 | S | A | 0.0000 | |
| 597 | P | A | 0.0000 | |
| 598 | F | A | 0.0000 | |
| 599 | T | A | 0.0000 | |
| 600 | W | A | 0.0000 | |
| 601 | G | A | 0.0000 | |
| 602 | K | A | -1.6985 | |
| 603 | T | A | -1.2758 | |
| 604 | R | A | -1.2964 | |
| 605 | E | A | -1.9218 | |
| 606 | A | A | 0.0000 | |
| 607 | Y | A | 0.0000 | |
| 608 | G | A | -0.5036 | |
| 609 | D | A | 0.0000 | |
| 610 | Y | A | 0.6544 | |
| 611 | L | A | 0.0000 | |
| 612 | V | A | -0.6700 | |
| 613 | R | A | -1.3384 | |
| 614 | E | A | -2.2589 | |
| 615 | L | A | -1.9622 | |
| 616 | N | A | -2.2665 | |
| 617 | N | A | -1.7360 | |
| 618 | G | A | -2.0518 | |
| 619 | N | A | -2.2900 | |
| 620 | G | A | -1.6400 | |
| 621 | A | A | 0.0000 | |
| 622 | P | A | 0.0000 | |
| 623 | Q | A | -1.0053 | |
| 624 | D | A | 0.0000 | |
| 625 | D | A | -2.1241 | |
| 626 | F | A | 0.0000 | |
| 627 | S | A | -1.1734 | |
| 628 | E | A | -0.7201 | |
| 629 | G | A | -1.0359 | |
| 630 | V | A | 0.0000 | |
| 631 | F | A | 0.0000 | |
| 632 | I | A | 0.0000 | |
| 633 | D | A | 0.0000 | |
| 634 | Y | A | 0.0000 | |
| 635 | R | A | 0.0000 | |
| 636 | G | A | 0.0000 | |
| 637 | F | A | 0.0000 | |
| 638 | D | A | 0.0000 | |
| 639 | K | A | -3.0755 | |
| 640 | R | A | -2.5216 | |
| 641 | N | A | -2.5366 | |
| 642 | E | A | -1.9156 | |
| 643 | T | A | -1.0008 | |
| 644 | P | A | 0.0000 | |
| 645 | I | A | -0.4800 | |
| 646 | Y | A | 0.0000 | |
| 647 | E | A | -0.4951 | |
| 648 | F | A | 0.0000 | |
| 649 | G | A | 0.0000 | |
| 650 | H | A | -0.4160 | |
| 651 | G | A | -0.0417 | |
| 652 | L | A | 0.2871 | |
| 653 | S | A | 0.2803 | |
| 654 | Y | A | -0.0994 | |
| 655 | T | A | 0.0000 | |
| 656 | T | A | -0.3260 | |
| 657 | F | A | -0.8084 | |
| 658 | N | A | -1.4321 | |
| 659 | Y | A | 0.0000 | |
| 660 | S | A | -0.5010 | |
| 661 | G | A | -0.2511 | |
| 662 | L | A | -0.3475 | |
| 663 | H | A | -1.2547 | |
| 664 | I | A | -0.3830 | |
| 665 | Q | A | -0.7270 | |
| 666 | V | A | 0.5152 | |
| 667 | L | A | -0.2483 | |
| 668 | N | A | -1.1085 | |
| 669 | A | A | -1.0325 | |
| 675 | V | A | 1.3037 | |
| 676 | A | A | 0.3213 | |
| 677 | T | A | -0.4776 | |
| 678 | E | A | -1.7799 | |
| 679 | T | A | -1.4466 | |
| 680 | G | A | -1.2182 | |
| 681 | A | A | -0.6849 | |
| 682 | A | A | -0.5508 | |
| 683 | P | A | -0.2830 | |
| 684 | T | A | -0.2831 | |
| 685 | F | A | -0.3100 | |
| 686 | G | A | -0.8947 | |
| 687 | Q | A | -1.2802 | |
| 688 | V | A | -0.7597 | |
| 689 | G | A | -1.4263 | |
| 690 | N | A | -1.8589 | |
| 691 | A | A | -1.4445 | |
| 692 | S | A | -1.7157 | |
| 693 | D | A | -2.1818 | |
| 694 | Y | A | 0.0000 | |
| 695 | V | A | -0.9908 | |
| 696 | Y | A | -0.8258 | |
| 697 | P | A | -1.2800 | |
| 698 | E | A | -1.8452 | |
| 699 | G | A | -1.2991 | |
| 700 | L | A | -0.6592 | |
| 701 | T | A | -0.8939 | |
| 702 | R | A | -1.4263 | |
| 703 | I | A | -0.8567 | |
| 704 | S | A | -0.8284 | |
| 705 | K | A | -0.7139 | |
| 706 | F | A | -0.3552 | |
| 707 | I | A | 0.0000 | |
| 708 | Y | A | -0.1136 | |
| 709 | P | A | 0.0000 | |
| 710 | W | A | -0.2478 | |
| 711 | L | A | 0.0000 | |
| 712 | N | A | -1.3726 | |
| 713 | S | A | -1.4267 | |
| 714 | T | A | -1.6911 | |
| 715 | D | A | -2.2280 | |
| 716 | L | A | -1.8199 | |
| 717 | K | A | -2.3388 | |
| 718 | A | A | -1.7291 | |
| 719 | S | A | -1.5880 | |
| 720 | S | A | -1.3516 | |
| 721 | G | A | -1.1422 | |
| 722 | D | A | -0.9937 | |
| 723 | P | A | -0.2582 | |
| 724 | Y | A | 0.6478 | |
| 725 | Y | A | -0.2603 | |
| 726 | G | A | -0.5673 | |
| 727 | V | A | -0.2439 | |
| 728 | D | A | -2.0259 | |
| 729 | T | A | -1.3583 | |
| 730 | A | A | -1.7577 | |
| 731 | E | A | -2.8611 | |
| 732 | H | A | -2.1948 | |
| 733 | V | A | -1.3630 | |
| 734 | P | A | -1.4456 | |
| 735 | E | A | -2.2322 | |
| 736 | G | A | -1.1496 | |
| 737 | A | A | 0.0000 | |
| 738 | T | A | -0.8247 | |
| 739 | D | A | -1.1956 | |
| 740 | G | A | -0.6939 | |
| 741 | S | A | -0.6238 | |
| 742 | P | A | -1.0434 | |
| 743 | Q | A | -1.0627 | |
| 744 | P | A | -0.9748 | |
| 745 | V | A | -0.2427 | |
| 746 | L | A | -0.2239 | |
| 747 | P | A | -0.0897 | |
| 748 | A | A | 0.0000 | |
| 749 | G | A | 0.0000 | |
| 750 | G | A | -0.1417 | |
| 751 | G | A | 0.0000 | |
| 752 | S | A | -0.7443 | |
| 753 | G | A | 0.0000 | |
| 754 | G | A | 0.0000 | |
| 755 | N | A | -0.4966 | |
| 756 | P | A | -0.7126 | |
| 757 | R | A | -1.7291 | |
| 758 | L | A | 0.0000 | |
| 759 | Y | A | -0.9011 | |
| 760 | D | A | -1.4591 | |
| 761 | E | A | -1.6068 | |
| 762 | L | A | 0.0000 | |
| 763 | I | A | 0.0000 | |
| 764 | R | A | -1.0518 | |
| 765 | V | A | 0.0000 | |
| 766 | S | A | -0.2112 | |
| 767 | V | A | 0.0000 | |
| 768 | T | A | -0.2627 | |
| 769 | V | A | 0.0000 | |
| 770 | K | A | -2.0482 | |
| 771 | N | A | 0.0000 | |
| 772 | T | A | -1.3441 | |
| 773 | G | A | -1.1935 | |
| 774 | R | A | -1.6552 | |
| 775 | V | A | -0.3052 | |
| 776 | A | A | -0.8971 | |
| 777 | G | A | 0.0000 | |
| 778 | D | A | -0.4153 | |
| 779 | A | A | 0.0000 | |
| 780 | V | A | 0.0000 | |
| 781 | P | A | 0.0000 | |
| 782 | Q | A | 0.0000 | |
| 783 | L | A | 0.0000 | |
| 784 | Y | A | 0.0000 | |
| 785 | V | A | 0.0000 | |
| 786 | S | A | -0.8480 | |
| 787 | L | A | 0.0000 | |
| 788 | G | A | -0.7641 | |
| 789 | G | A | -0.8150 | |
| 790 | P | A | -1.1467 | |
| 791 | N | A | -2.0240 | |
| 792 | E | A | -1.6661 | |
| 793 | P | A | 0.0000 | |
| 794 | K | A | -2.2521 | |
| 795 | V | A | -1.1157 | |
| 796 | V | A | 0.0000 | |
| 797 | L | A | 0.0000 | |
| 798 | R | A | 0.0000 | |
| 799 | K | A | -0.3380 | |
| 800 | F | A | 0.0000 | |
| 801 | D | A | -0.8457 | |
| 802 | R | A | -0.6957 | |
| 803 | L | A | -0.1790 | |
| 804 | T | A | -0.8462 | |
| 805 | L | A | 0.0000 | |
| 806 | K | A | -2.6096 | |
| 807 | P | A | -1.9659 | |
| 808 | S | A | -1.9874 | |
| 809 | E | A | -2.8332 | |
| 810 | E | A | -2.6491 | |
| 811 | T | A | -0.4176 | |
| 812 | V | A | 1.2319 | |
| 813 | W | A | 0.0000 | |
| 814 | T | A | 0.0905 | |
| 815 | T | A | -0.2997 | |
| 816 | T | A | -0.6890 | |
| 817 | L | A | 0.0000 | |
| 818 | T | A | -0.9902 | |
| 819 | R | A | -1.0061 | |
| 820 | R | A | 0.0000 | |
| 821 | D | A | 0.0000 | |
| 822 | L | A | 0.0000 | |
| 823 | S | A | 0.0000 | |
| 824 | N | A | 0.0000 | |
| 825 | W | A | 0.0000 | |
| 826 | D | A | -0.0365 | |
| 827 | V | A | 0.6619 | |
| 828 | A | A | 0.4151 | |
| 829 | A | A | 0.1135 | |
| 830 | Q | A | -0.0621 | |
| 831 | D | A | -0.2646 | |
| 832 | W | A | 0.0136 | |
| 833 | V | A | 0.2323 | |
| 834 | I | A | -0.1386 | |
| 835 | T | A | -0.0726 | |
| 836 | S | A | -0.1514 | |
| 837 | Y | A | 0.3017 | |
| 838 | P | A | -0.4252 | |
| 839 | K | A | 0.0000 | |
| 840 | K | A | -1.1479 | |
| 841 | V | A | 0.0000 | |
| 842 | H | A | -0.7337 | |
| 843 | V | A | 0.0000 | |
| 844 | G | A | 0.0000 | |
| 845 | S | A | -0.5598 | |
| 846 | S | A | 0.0000 | |
| 847 | S | A | 0.0000 | |
| 848 | R | A | -1.3350 | |
| 849 | Q | A | -1.3783 | |
| 850 | L | A | -0.8054 | |
| 851 | P | A | -0.7902 | |
| 852 | L | A | -0.6030 | |
| 853 | H | A | -1.2083 | |
| 854 | A | A | -0.7512 | |
| 855 | A | A | -0.7304 | |
| 856 | L | A | -0.6031 | |
| 857 | P | A | -0.9005 | |
| 858 | K | A | -1.6332 | |
| 859 | V | A | -0.9506 | |
| 860 | Q | A | -1.4415 |
Automated mutations analysis
In the automated mutations mode, the server selects aggregation prone resides
and each selected residue is mutated to glutamic acid, lysine, aspartic acid and arginine.
The table below shows 2 best scored mutants for each mutated residue. Protein variants
are ordered according to the mutation effect they had on protein stability
(energetic effect) together with the difference in the average per-residue aggregation score
between the wild type and the mutant (in the table green values indicate a positive change,
grey are neutral, and orange/red mean destabilizing or more aggregation prone mutants).
Summary for all the mutants can be found in this
CSV file.
Mutant |
Energetic effect |
Score comparison |
|||
| LR22A | -0.1605 | -0.008 | View | CSV | PDB |
| AK23A | -0.273 | -0.0002 | View | CSV | PDB |
| FK24A | 0.5746 | -0.0148 | View | CSV | PDB |
| FE24A | 0.6581 | -0.0149 | View | CSV | PDB |
| LK22A | 0.3835 | -0.0079 | View | CSV | PDB |
| PE27A | 0.5011 | -0.004 | View | CSV | PDB |
| PR27A | 0.6845 | -0.0052 | View | CSV | PDB |
| FR28A | 1.3359 | -0.0057 | View | CSV | PDB |
| AR23A | 0.6183 | -0.0026 | View | CSV | PDB |
| PK26A | 1.3815 | -0.0048 | View | CSV | PDB |
| PD26A | 1.3776 | -0.0041 | View | CSV | PDB |
| FK28A | 1.3322 | -0.0032 | View | CSV | PDB |
| SK25A | 0.6307 | -0.0001 | View | CSV | PDB |
| SR25A | -0.0849 | 0.0003 | View | CSV | PDB |
ALA alanine
ARG arginine
ASN asparagine
ASP aspartic acid
CYS cysteine
GLN glutamine
GLU glutamic acid
GLY glycine
HIS histidine
ILE isoleucine
LEU leucine
LYS lysine
MET methionine
PHE phenylalanine
PRO proline
SER serine
THR threonine
TRP tryptophan
TYR tyrosine
VAL valine