Project name: b4d52644f7aefdc

Chain sequence(s)	A: LIVTQTMKGLDIQKVAGTWYSLAMAASDISLLDAQSAPLRVYVEELKPTPEGDLEILLQKWENGECAQKKIIAEKTKIPAVFKIDALNENKVLVLDTDYKKYLLFCMENSAEPEQSLACQCLVRTPEVDDEALEKFDKALKALPMHIRLSFNPTQLEEQCHI
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:34)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:35)

• Minimal score value: -3.5483
• Maximal score value: 2.7703
• Average score: -1.007
• Total score value: -163.1336

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
17	L	A	2.7703
18	I	A	2.6441
19	V	A	2.6142
20	T	A	0.9047
21	Q	A	-0.7777
22	T	A	-0.7826
23	M	A	-1.2456
24	K	A	-2.0776
25	G	A	-1.3364
26	L	A	0.0000
27	D	A	-1.7889
28	I	A	-1.6553
29	Q	A	-2.3328
30	K	A	-2.7522
31	V	A	0.0000
32	A	A	-1.2863
33	G	A	-0.9974
34	T	A	-0.5153
35	W	A	0.0000
36	Y	A	-0.5720
37	S	A	0.0000
38	L	A	0.0000
39	A	A	0.0000
40	M	A	0.0000
41	A	A	0.0000
42	A	A	0.0000
43	S	A	0.0000
44	D	A	-0.8336
45	I	A	0.1463
46	S	A	-0.4392
47	L	A	-0.5406
48	L	A	0.0000
49	D	A	-1.8213
50	A	A	-1.3585
51	Q	A	-1.5953
52	S	A	-1.7347
53	A	A	0.0000
54	P	A	-0.8346
55	L	A	0.0000
56	R	A	-0.8428
57	V	A	0.0000
58	Y	A	0.0000
59	V	A	0.0000
60	E	A	-0.7929
61	E	A	-1.0270
62	L	A	0.0000
63	K	A	-1.2748
64	P	A	-1.5040
65	T	A	-1.5458
66	P	A	-1.4908
67	E	A	-2.5711
68	G	A	-2.4069
69	D	A	-2.3875
70	L	A	0.0000
71	E	A	-0.6837
72	I	A	0.0000
73	L	A	-1.0603
74	L	A	0.0000
75	Q	A	-1.4926
76	K	A	0.0000
77	W	A	-1.6472
78	E	A	-2.5704
79	N	A	-2.4904
80	G	A	-2.3320
81	E	A	-2.8648
82	C	A	-1.6888
83	A	A	-1.7395
84	Q	A	-2.2206
85	K	A	-1.9598
86	K	A	-1.8178
87	I	A	0.0000
88	I	A	0.2049
89	A	A	0.0000
90	E	A	-3.1602
91	K	A	-3.2609
92	T	A	-2.1219
93	K	A	-1.7242
94	I	A	-0.6924
95	P	A	-1.1242
96	A	A	0.0000
97	V	A	0.0000
98	F	A	0.0000
99	K	A	-2.4254
100	I	A	0.0000
101	D	A	-2.2857
102	A	A	-1.2975
103	L	A	-0.8945
104	N	A	-1.7511
105	E	A	0.0000
106	N	A	-1.8346
107	K	A	-1.7284
108	V	A	0.0000
109	L	A	0.0000
110	V	A	0.0000
111	L	A	0.0000
112	D	A	-1.0699
113	T	A	0.0000
114	D	A	-1.5737
115	Y	A	-2.0103
116	K	A	-2.8086
117	K	A	-2.7506
118	Y	A	0.0000
119	L	A	0.0000
120	L	A	0.0000
121	F	A	0.0000
122	C	A	0.0000
123	M	A	0.0000
124	E	A	-1.5938
125	N	A	-2.0663
126	S	A	-1.3593
127	A	A	-1.4227
128	E	A	-2.9071
129	P	A	-2.2742
130	E	A	-2.9200
131	Q	A	-2.7042
132	S	A	0.0000
133	L	A	0.0000
134	A	A	0.0000
135	C	A	0.0000
136	Q	A	0.0000
137	C	A	0.0000
138	L	A	0.0000
139	V	A	0.0000
140	R	A	-1.6473
141	T	A	-1.2641
142	P	A	-1.5427
143	E	A	-1.8514
144	V	A	-0.4230
145	D	A	-1.7845
146	D	A	-2.9491
147	E	A	-3.3096
148	A	A	0.0000
149	L	A	-2.2552
150	E	A	-3.5483
151	K	A	-3.0039
152	F	A	0.0000
153	D	A	-2.9068
154	K	A	-3.2792
155	A	A	-2.2133
156	L	A	0.0000
157	K	A	-2.4171
158	A	A	-0.7021
159	L	A	-0.4391
160	P	A	-0.7573
161	M	A	-0.7496
162	H	A	-0.7107
163	I	A	-0.5607
164	R	A	-1.0706
165	L	A	-0.4331
166	S	A	-0.2990
167	F	A	0.0000
168	N	A	-1.5505
169	P	A	-1.6484
170	T	A	-1.5046
171	Q	A	-1.4401
172	L	A	0.0000
173	E	A	-2.9935
174	E	A	-2.4551
175	Q	A	-2.1096
176	C	A	0.0000
177	H	A	0.0000
178	I	A	0.8525