Project name: FEFEFEGGGKGH12

Chain sequence(s)	A: FEFEFEGGGKGH; C: FEFEFEGGGKGH; B: FEFEFEGGGKGH; E: FEFEFEGGGKGH; D: FEFEFEGGGKGH; G: FEFEFEGGGKGH; F: FEFEFEGGGKGH; I: FEFEFEGGGKGH; H: FEFEFEGGGKGH; K: FEFEFEGGGKGH; J: FEFEFEGGGKGH; L: FEFEFEGGGKGH
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:08:42)
[INFO]       Main:     Simulation completed successfully.                                          (00:08:46)

• Minimal score value: -6.428
• Maximal score value: 1.026
• Average score: -2.4496
• Total score value: -352.7406

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	-0.3913
2	E	A	-3.2699
3	F	A	0.0000
4	E	A	-5.6217
5	F	A	0.0000
6	E	A	-5.0638
7	G	A	-3.0746
8	G	A	-2.5242
9	G	A	-2.6189
10	K	A	-3.3677
11	G	A	-2.8189
12	H	A	-2.4709
1	F	B	0.2494
2	E	B	-3.1491
3	F	B	0.0000
4	E	B	-5.9202
5	F	B	0.0000
6	E	B	-5.0922
7	G	B	-3.2926
8	G	B	-2.9103
9	G	B	-2.5160
10	K	B	-2.9758
11	G	B	0.0000
12	H	B	-2.1248
1	F	C	0.2891
2	E	C	-2.8983
3	F	C	0.0000
4	E	C	-6.3126
5	F	C	0.0000
6	E	C	-5.6246
7	G	C	0.0000
8	G	C	-2.7864
9	G	C	-2.9049
10	K	C	-3.4680
11	G	C	-2.8802
12	H	C	-2.5435
1	F	D	0.6632
2	E	D	-2.3696
3	F	D	0.0000
4	E	D	-4.6127
5	F	D	0.0000
6	E	D	-4.4048
7	G	D	-2.9222
8	G	D	-2.5902
9	G	D	-2.5857
10	K	D	-2.8572
11	G	D	-2.7383
12	H	D	-2.4012
1	F	E	1.0260
2	E	E	-1.7748
3	F	E	-1.7905
4	E	E	-3.5812
5	F	E	-2.6802
6	E	E	-3.4903
7	G	E	-2.1452
8	G	E	-2.4881
9	G	E	-2.3566
10	K	E	-2.9527
11	G	E	-2.6122
12	H	E	-2.1132
1	F	F	0.4902
2	E	F	-2.3095
3	F	F	-2.5050
4	E	F	-4.2758
5	F	F	-3.4060
6	E	F	-4.1456
7	G	F	-2.4882
8	G	F	-2.6510
9	G	F	-2.7827
10	K	F	-3.7651
11	G	F	-2.8706
12	H	F	-2.1755
1	F	G	-0.0999
2	E	G	-2.8384
3	F	G	0.0000
4	E	G	-4.5823
5	F	G	-3.5027
6	E	G	-4.0522
7	G	G	-2.8175
8	G	G	-2.6754
9	G	G	-2.9253
10	K	G	-3.7696
11	G	G	-3.0138
12	H	G	-2.2420
1	F	H	0.0214
2	E	H	-2.5176
3	F	H	0.0000
4	E	H	-4.4557
5	F	H	0.0000
6	E	H	-4.3397
7	G	H	-2.9113
8	G	H	-2.6358
9	G	H	-2.5173
10	K	H	-3.5975
11	G	H	-2.8240
12	H	H	-2.1420
1	F	I	0.5727
2	E	I	-2.8939
3	F	I	-3.2411
4	E	I	-5.1628
5	F	I	0.0000
6	E	I	-5.1921
7	G	I	-3.1226
8	G	I	-2.4853
9	G	I	-2.5727
10	K	I	-3.4943
11	G	I	-2.5645
12	H	I	-2.1448
1	F	J	0.7831
2	E	J	-2.6390
3	F	J	0.0000
4	E	J	-6.4280
5	F	J	0.0000
6	E	J	-5.7010
7	G	J	-3.2505
8	G	J	-2.8894
9	G	J	-2.7010
10	K	J	-3.5447
11	G	J	-2.5575
12	H	J	-2.1960
1	F	K	0.4929
2	E	K	-1.8906
3	F	K	-2.0869
4	E	K	-3.9169
5	F	K	-3.2531
6	E	K	-3.8591
7	G	K	0.0000
8	G	K	-2.5367
9	G	K	-2.6656
10	K	K	-3.3275
11	G	K	-2.7461
12	H	K	-2.0580
1	F	L	0.7572
2	E	L	-1.9578
3	F	L	0.0000
4	E	L	-3.7754
5	F	L	-3.0109
6	E	L	-3.8762
7	G	L	-2.4993
8	G	L	-2.3676
9	G	L	-2.4988
10	K	L	-3.1496
11	G	L	-2.1392
12	H	L	-1.7660