Project name: 5615

Chain sequence(s)	H: QVQLVESGGGLVQPGGSLRLSCAASGLGPYPFSSYGWAWFRQAPGQGLEAVAAIGGDGSTTIYHPSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCAAGGGPVQDGRYDYWGQGTLVTVS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:45)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:45)

• Minimal score value: -3.0531
• Maximal score value: 1.7246
• Average score: -0.5817
• Total score value: -71.5449

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-1.5199
2	V	H	-0.8592
3	Q	H	-1.0645
4	L	H	0.0000
5	V	H	1.2000
6	E	H	0.0000
7	S	H	-0.0926
8	G	H	-0.6518
9	G	H	0.2288
10	G	H	0.7466
11	L	H	1.4417
12	V	H	-0.0815
13	Q	H	-1.4189
14	P	H	-1.9381
15	G	H	-1.7257
16	G	H	-1.1902
17	S	H	-1.4540
18	L	H	-0.7998
19	R	H	-1.6847
20	L	H	0.0000
21	S	H	-0.1823
22	C	H	0.0000
23	A	H	-0.1250
24	A	H	0.0000
25	S	H	-0.7813
26	G	H	-1.1863
27	L	H	-0.5952
28	G	H	-0.4440
29	P	H	-0.0848
30	Y	H	0.4617
31	P	H	-0.1342
32	F	H	0.0000
33	S	H	-0.8034
34	S	H	-0.1703
35	Y	H	0.0000
36	G	H	0.0000
37	W	H	0.0000
38	A	H	0.0000
39	W	H	0.0000
40	F	H	0.4051
41	R	H	0.0000
42	Q	H	-0.3927
43	A	H	-0.8685
44	P	H	-0.9709
45	G	H	-1.2481
46	Q	H	-1.6914
47	G	H	-0.9473
48	L	H	0.1939
49	E	H	-0.2759
50	A	H	0.2813
51	V	H	0.0000
52	A	H	0.0000
53	A	H	0.6162
54	I	H	0.0000
55	G	H	-0.3807
56	G	H	-0.9998
57	D	H	-2.2307
58	G	H	-1.4934
59	S	H	-0.9748
60	T	H	-0.1939
61	T	H	0.8338
62	I	H	1.7040
63	Y	H	0.2470
64	H	H	-0.5482
65	P	H	-0.8984
66	S	H	-1.1631
67	V	H	0.0000
68	K	H	-1.9123
69	G	H	-1.7254
70	R	H	-1.6778
71	F	H	0.0000
72	T	H	-0.7056
73	I	H	0.0000
74	S	H	-0.4633
75	R	H	-1.3104
76	D	H	-1.8633
77	N	H	-2.1132
78	S	H	-1.6766
79	K	H	-2.4351
80	N	H	-1.8622
81	T	H	-1.0199
82	L	H	0.0000
83	Y	H	-0.4211
84	L	H	0.0000
85	Q	H	-1.2793
86	M	H	0.0000
87	N	H	-2.1783
88	S	H	-1.7591
89	L	H	0.0000
90	R	H	-3.0531
91	A	H	-2.0755
92	E	H	-2.4891
93	D	H	0.0000
94	T	H	-0.5133
95	A	H	0.0000
96	V	H	0.8760
97	Y	H	0.0000
98	Y	H	0.5379
99	C	H	0.0000
100	A	H	0.0000
101	A	H	0.0000
102	G	H	0.0000
103	G	H	-1.3079
104	G	H	-1.0069
105	P	H	-0.5859
106	V	H	-0.1445
107	Q	H	-1.6843
108	D	H	-2.5316
109	G	H	-2.0841
110	R	H	-2.6663
111	Y	H	-1.2874
112	D	H	-1.8227
113	Y	H	-0.5862
114	W	H	0.1560
115	G	H	-0.1138
116	Q	H	-0.8207
117	G	H	0.1777
118	T	H	0.6490
119	L	H	1.7246
120	V	H	0.0000
121	T	H	0.2978
122	V	H	0.0000
123	S	H	-0.8823