Project name: bd07da08ccbbbb

Chain sequence(s)	H: QFQLVQSGAEVKKPGASVKVSCKASGYSFTDYNVNWVRQAPGQGLEWIGVINPKYGTTRYNQKFKGRATLTVDKSTSTAYMELSSLRSEDTAVYYCTRGLNAWDYWGQGTLVTVSS; L: DIQMTQSPSSLSASVGDRVTITCGASENIYGALNWYQQKPGKAPKLLIYGATNLEDGVPSRFSGSGSGRDYTFTISSLQPEDIATYYCQNVLTTPYTFGQGTKLEIK
Selected Chain(s)	H,L
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:59)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:01)

• Minimal score value: -3.1986
• Maximal score value: 1.0792
• Average score: -0.6232
• Total score value: -138.9828

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	Q	H	-0.8534
2	F	H	0.3703
3	Q	H	-0.2388
4	L	H	0.0000
5	V	H	0.8356
6	Q	H	0.0000
7	S	H	-0.3216
8	G	H	-0.3493
9	A	H	0.3791
11	E	H	0.2743
12	V	H	1.0792
13	K	H	-0.8558
14	K	H	-2.0774
15	P	H	-1.8747
16	G	H	-1.4133
17	A	H	-1.1539
18	S	H	-1.2176
19	V	H	0.0000
20	K	H	-1.4992
21	V	H	0.0000
22	S	H	-0.3227
23	C	H	0.0000
24	K	H	-0.6347
25	A	H	0.0000
26	S	H	-0.3333
27	G	H	-0.5489
28	Y	H	-0.3414
29	S	H	-0.5454
30	F	H	0.0000
35	T	H	-1.4604
36	D	H	-1.8335
37	Y	H	-0.6570
38	N	H	-0.5400
39	V	H	0.0000
40	N	H	0.0000
41	W	H	0.0000
42	V	H	0.0000
43	R	H	-0.2865
44	Q	H	-0.5487
45	A	H	-0.9070
46	P	H	-0.9182
47	G	H	-1.2174
48	Q	H	-1.8466
49	G	H	-1.3389
50	L	H	0.0000
51	E	H	-0.9059
52	W	H	0.0000
53	I	H	0.0000
54	G	H	0.0000
55	V	H	-0.5309
56	I	H	0.0000
57	N	H	-0.6608
58	P	H	0.0000
59	K	H	-1.2198
62	Y	H	0.6259
63	G	H	-0.3783
64	T	H	-0.3974
65	T	H	-0.8161
66	R	H	-2.1607
67	Y	H	-1.8572
68	N	H	-2.1759
69	Q	H	-3.0530
70	K	H	-2.9519
71	F	H	0.0000
72	K	H	-3.1986
74	G	H	-1.9950
75	R	H	-1.7478
76	A	H	0.0000
77	T	H	-1.0188
78	L	H	0.0000
79	T	H	-0.3536
80	V	H	-0.6044
81	D	H	-1.3385
82	K	H	-2.0752
83	S	H	-1.1272
84	T	H	-0.9671
85	S	H	-1.1704
86	T	H	-0.7708
87	A	H	0.0000
88	Y	H	-0.3433
89	M	H	0.0000
90	E	H	-1.0556
91	L	H	0.0000
92	S	H	-1.0702
93	S	H	-1.1491
94	L	H	0.0000
95	R	H	-2.6243
96	S	H	-2.1350
97	E	H	-2.3986
98	D	H	0.0000
99	T	H	-0.6357
100	A	H	0.0000
101	V	H	0.6113
102	Y	H	0.0000
103	Y	H	0.0000
104	C	H	0.0000
105	T	H	0.0000
106	R	H	0.0000
107	G	H	0.0000
108	L	H	0.5037
109	N	H	-0.4140
114	A	H	0.0441
115	W	H	0.0000
116	D	H	-0.0545
117	Y	H	0.2161
118	W	H	0.1048
119	G	H	0.0000
120	Q	H	-1.1231
121	G	H	-0.4050
122	T	H	0.0000
123	L	H	1.0185
124	V	H	0.0000
125	T	H	-0.0005
126	V	H	0.0000
127	S	H	-0.8794
128	S	H	-0.9272
1	D	L	-2.3668
2	I	L	0.0000
3	Q	L	-1.9818
4	M	L	0.0000
5	T	L	-0.8924
6	Q	L	0.0000
7	S	L	-0.4307
8	P	L	-0.6056
9	S	L	-0.8784
10	S	L	-1.0891
11	L	L	-0.8227
12	S	L	-1.2136
13	A	L	0.0000
14	S	L	-0.8109
15	V	L	0.0230
16	G	L	-0.6193
17	D	L	-1.7030
18	R	L	-2.2413
19	V	L	0.0000
20	T	L	-0.6185
21	I	L	0.0000
22	T	L	-0.5362
23	C	L	0.0000
24	G	L	-1.6490
25	A	L	0.0000
26	S	L	-2.0042
27	E	L	-2.4536
28	N	L	-1.7168
29	I	L	0.0000
36	Y	L	0.5055
37	G	L	-0.0055
38	A	L	0.2779
39	L	L	0.0000
40	N	L	0.0000
41	W	L	0.0000
42	Y	L	0.0000
43	Q	L	0.0000
44	Q	L	0.0000
45	K	L	-1.6252
46	P	L	-1.1576
47	G	L	-1.6299
48	K	L	-2.5203
49	A	L	-1.4555
50	P	L	0.0000
51	K	L	-0.8509
52	L	L	0.0000
53	L	L	0.0000
54	I	L	0.0000
55	Y	L	0.0898
56	G	L	-0.1437
57	A	L	0.0000
65	T	L	-0.4567
66	N	L	-0.7311
67	L	L	-0.3138
68	E	L	-1.0507
69	D	L	-2.0383
70	G	L	-1.2611
71	V	L	-0.7569
72	P	L	-0.5678
74	S	L	-0.3873
75	R	L	-0.7586
76	F	L	0.0000
77	S	L	-0.3906
78	G	L	-0.3279
79	S	L	-0.8481
80	G	L	-1.0974
83	S	L	-1.0351
84	G	L	-1.3661
85	R	L	-2.5722
86	D	L	-2.6957
87	Y	L	0.0000
88	T	L	-0.6538
89	F	L	0.0000
90	T	L	-0.5924
91	I	L	0.0000
92	S	L	-1.2594
93	S	L	-1.1096
94	L	L	0.0000
95	Q	L	-0.6267
96	P	L	-1.0410
97	E	L	-1.6444
98	D	L	0.0000
99	I	L	-0.6381
100	A	L	0.0000
101	T	L	-1.0004
102	Y	L	0.0000
103	Y	L	0.0000
104	C	L	0.0000
105	Q	L	0.0000
106	N	L	0.0000
107	V	L	0.0000
108	L	L	0.5688
109	T	L	-0.1032
114	T	L	-0.5905
115	P	L	-1.1061
116	Y	L	-0.3060
117	T	L	-0.6299
118	F	L	0.0000
119	G	L	0.0000
120	Q	L	-1.6213
121	G	L	0.0000
122	T	L	0.0000
123	K	L	-1.8489
124	L	L	0.0000
125	E	L	-1.6540
126	I	L	-0.9399
127	K	L	-1.6408