Project name: bd5f60f5776bb32

Chain sequence(s)	A: MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKPEAAKEEDIRKLVTMYPDNITIAEERKKRLSFFTGFDSVEHKKSENAEVLRRIAENAMASRRSSKSRTDDGPGPGKGEVVVNGRIAYVPQGPGPGRASIVFFDRNPIGNIAAYHLSFLTFSWGPGPGVFKNVSLRY
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:04:51)
[INFO]       Main:     Simulation completed successfully.                                          (00:04:53)

• Minimal score value: -4.7266
• Maximal score value: 5.8954
• Average score: -0.3867
• Total score value: -76.9459

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	1.4389
2	R	A	0.6111
3	V	A	2.8449
4	L	A	3.4627
5	Y	A	3.4955
6	L	A	3.7403
7	L	A	4.2018
8	F	A	4.6815
9	S	A	4.5559
10	F	A	5.5167
11	L	A	5.4607
12	F	A	5.8470
13	I	A	5.8954
14	F	A	5.6270
15	L	A	4.9256
16	M	A	3.9636
17	P	A	2.6743
18	L	A	2.9833
19	P	A	1.0989
20	G	A	1.0332
21	V	A	2.5189
22	F	A	2.5125
23	G	A	0.6268
24	G	A	0.2368
25	I	A	0.2718
26	G	A	-0.1032
27	D	A	-0.3923
28	P	A	0.5628
29	V	A	1.3946
30	T	A	0.2200
31	C	A	0.0000
32	L	A	1.2370
33	K	A	-0.6044
34	S	A	-0.2370
35	G	A	-0.5867
36	A	A	0.0000
37	I	A	0.6209
38	C	A	0.9347
39	H	A	0.4383
40	P	A	1.0168
41	V	A	2.2008
42	F	A	1.9676
43	C	A	-0.1373
44	P	A	-1.2413
45	R	A	-2.7069
46	R	A	-3.1918
47	Y	A	-2.3868
48	K	A	-2.6176
49	Q	A	-1.5471
50	I	A	-0.6183
51	G	A	-0.8512
52	T	A	-0.7412
53	C	A	0.0000
54	G	A	-0.2074
55	L	A	0.7396
56	P	A	0.2492
57	G	A	0.3589
58	T	A	0.4572
59	K	A	-0.1255
60	C	A	0.0000
61	C	A	0.0000
62	K	A	-1.7057
63	K	A	-2.7155
64	P	A	-2.2474
65	E	A	-2.4873
66	A	A	-1.7355
67	A	A	-2.1989
68	K	A	-4.1546
69	E	A	-4.3736
70	E	A	-4.7266
71	D	A	-4.1146
72	I	A	-2.8657
73	R	A	-3.6778
74	K	A	-3.1417
75	L	A	-1.0235
76	V	A	-0.5820
77	T	A	-0.4092
78	M	A	0.8138
79	Y	A	0.7732
80	P	A	-0.3355
81	D	A	-1.6889
82	N	A	-1.2169
83	I	A	0.3808
84	T	A	-0.0521
85	I	A	-0.0110
86	A	A	-1.0917
87	E	A	-3.1120
88	E	A	-4.0532
89	R	A	-4.6169
90	K	A	-4.3716
91	K	A	-3.8551
92	R	A	-2.4177
93	L	A	0.2577
94	S	A	1.1897
95	F	A	2.8571
96	F	A	3.1053
97	T	A	1.4372
98	G	A	0.7836
99	F	A	1.2504
100	D	A	-0.7793
101	S	A	-0.3114
102	V	A	0.0315
103	E	A	-2.2622
104	H	A	-2.9183
105	K	A	-3.7285
106	K	A	-3.7279
107	S	A	-2.8838
108	E	A	-3.3731
109	N	A	-2.7683
110	A	A	-1.8971
111	E	A	-2.2261
112	V	A	-0.9245
113	L	A	-1.0248
114	R	A	-2.6328
115	R	A	-2.3684
116	I	A	0.1370
117	A	A	-0.9445
118	E	A	-2.4466
119	N	A	-2.1369
120	A	A	-0.9169
121	M	A	-0.9614
122	A	A	-1.5318
123	S	A	-2.0558
124	R	A	-3.0244
125	R	A	-3.0704
126	S	A	-2.2809
127	S	A	-2.4337
128	K	A	-2.8840
129	S	A	-2.2681
130	R	A	-3.0261
131	T	A	-2.5627
132	D	A	-3.2855
133	D	A	-3.2228
134	G	A	-2.0398
135	P	A	-1.5055
136	G	A	-1.5209
137	P	A	-1.3619
138	G	A	-2.0517
139	K	A	-2.6525
140	G	A	-1.1767
141	E	A	-0.6450
142	V	A	0.6834
143	V	A	1.2762
144	V	A	0.8486
145	N	A	-1.0144
146	G	A	-0.9639
147	R	A	-1.1425
148	I	A	0.8104
149	A	A	0.8544
150	Y	A	0.7197
151	V	A	0.1233
152	P	A	0.0000
153	Q	A	-1.6409
154	G	A	-1.5146
155	P	A	-1.1725
156	G	A	-0.9047
157	P	A	-0.8890
158	G	A	-1.3658
159	R	A	-1.8728
160	A	A	-0.6827
161	S	A	0.3069
162	I	A	1.1655
163	V	A	1.6305
164	F	A	1.5456
165	F	A	0.7203
166	D	A	-1.7325
167	R	A	-2.0058
168	N	A	-1.0822
169	P	A	-0.1714
170	I	A	1.2526
171	G	A	-0.4233
172	N	A	-0.9365
173	I	A	-0.4735
174	A	A	-0.7257
175	A	A	-0.0783
176	Y	A	1.1084
177	H	A	0.6472
178	L	A	1.2839
179	S	A	0.0000
180	F	A	0.4788
181	L	A	0.3240
182	T	A	-0.4833
183	F	A	0.0000
184	S	A	-0.5984
185	W	A	-0.4419
186	G	A	-0.5649
187	P	A	-0.4591
188	G	A	-0.3251
189	P	A	-0.7408
190	G	A	-0.8264
191	V	A	0.1268
192	F	A	0.1110
193	K	A	-1.4359
194	N	A	-0.8584
195	V	A	0.9335
196	S	A	0.5327
197	L	A	0.4344
198	R	A	-0.5120
199	Y	A	0.6456