Project name: bda9f997636c8c

Chain sequence(s)	A: GEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLVSRHWKRGFILKRGEPPPGKPADDAGLV
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:13)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:14)

• Minimal score value: -3.0069
• Maximal score value: 3.0743
• Average score: -0.9938
• Total score value: -229.5739

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-1.4477
2	E	A	-2.2692
3	P	A	-1.4842
4	P	A	-1.3258
5	P	A	-1.3007
6	G	A	-1.6067
7	K	A	-2.3886
8	P	A	-2.0392
9	A	A	-1.9828
10	D	A	-2.9620
11	D	A	-2.4766
12	A	A	-1.0620
13	G	A	0.1508
14	L	A	1.5532
15	V	A	1.5910
16	S	A	-0.0154
17	R	A	-1.6651
18	H	A	-1.8727
19	W	A	-1.1225
20	K	A	-2.4599
21	R	A	-2.1206
22	G	A	-0.0263
23	F	A	2.3115
24	I	A	2.6896
25	L	A	1.7026
26	K	A	-1.4054
27	R	A	-2.7259
28	G	A	-2.5829
29	E	A	-2.8808
30	P	A	-1.4807
31	P	A	-1.1093
32	P	A	-1.3073
33	G	A	-1.5541
34	K	A	-2.0922
35	P	A	-1.7800
36	A	A	-1.7589
37	D	A	-2.7401
38	D	A	-2.6113
39	A	A	-0.8074
40	G	A	0.1036
41	L	A	1.7275
42	V	A	1.7154
43	S	A	0.0048
44	R	A	-1.6885
45	H	A	-1.7138
46	W	A	-1.0687
47	K	A	-2.3481
48	R	A	-2.3637
49	G	A	-0.0498
50	F	A	2.3969
51	I	A	3.0743
52	L	A	1.5440
53	K	A	-1.4667
54	R	A	-2.7209
55	G	A	-2.6256
56	E	A	-2.8904
57	P	A	-1.6729
58	P	A	-1.2832
59	P	A	-1.2780
60	G	A	-1.5600
61	K	A	-2.3080
62	P	A	-1.8564
63	A	A	-1.8339
64	D	A	-2.9229
65	D	A	-2.5943
66	A	A	-0.7836
67	G	A	0.0968
68	L	A	1.6585
69	V	A	1.5339
70	S	A	0.0089
71	R	A	-1.8803
72	H	A	-1.7744
73	W	A	-1.1990
74	K	A	-2.4021
75	R	A	-2.2711
76	G	A	-0.3535
77	F	A	2.4792
78	I	A	2.7362
79	L	A	1.4793
80	K	A	-2.0009
81	R	A	-2.9717
82	G	A	-2.6565
83	E	A	-2.8962
84	P	A	-1.5277
85	P	A	-0.9713
86	P	A	-1.2845
87	G	A	-1.5515
88	K	A	-2.0921
89	P	A	-1.7870
90	A	A	-1.7215
91	D	A	-2.7336
92	D	A	-2.5790
93	A	A	-0.9301
94	G	A	0.1885
95	L	A	1.6865
96	V	A	1.6786
97	S	A	0.1819
98	R	A	-1.6635
99	H	A	-1.7329
100	W	A	-1.1760
101	K	A	-2.4252
102	R	A	-2.0220
103	G	A	-0.0444
104	F	A	2.2046
105	I	A	2.7170
106	L	A	1.6777
107	K	A	-1.3612
108	R	A	-2.7594
109	G	A	-2.6736
110	E	A	-2.8355
111	P	A	-1.4725
112	P	A	-1.2269
113	P	A	-1.2873
114	G	A	-1.5613
115	K	A	-2.1227
116	P	A	-1.8563
117	A	A	-1.6901
118	D	A	-2.7410
119	D	A	-2.6128
120	A	A	-0.9014
121	G	A	0.0961
122	L	A	1.6874
123	V	A	1.5804
124	S	A	0.0292
125	R	A	-1.5186
126	H	A	-1.7197
127	W	A	-1.1884
128	K	A	-2.3646
129	R	A	-2.0427
130	G	A	0.0670
131	F	A	2.2811
132	I	A	2.6673
133	L	A	1.5801
134	K	A	-1.3984
135	R	A	-2.6344
136	G	A	-2.6145
137	E	A	-2.8924
138	P	A	-1.7307
139	P	A	-1.2904
140	P	A	-1.2921
141	G	A	-1.5614
142	K	A	-2.1180
143	P	A	-1.7579
144	A	A	-1.7047
145	D	A	-2.7883
146	D	A	-2.8256
147	A	A	-0.9303
148	G	A	0.0862
149	L	A	2.2349
150	V	A	1.9983
151	S	A	-0.1266
152	R	A	-1.7815
153	H	A	-1.9075
154	W	A	-1.0083
155	K	A	-2.3572
156	R	A	-2.1040
157	G	A	0.0365
158	F	A	2.4797
159	I	A	2.6782
160	L	A	1.5945
161	K	A	-1.3991
162	R	A	-2.6722
163	G	A	-2.6101
164	E	A	-2.8891
165	P	A	-1.7270
166	P	A	-1.2859
167	P	A	-1.2694
168	G	A	-1.5616
169	K	A	-2.1180
170	P	A	-1.8065
171	A	A	-1.7689
172	D	A	-2.7115
173	D	A	-2.7754
174	A	A	-0.9629
175	G	A	0.3978
176	L	A	1.9201
177	V	A	1.9111
178	S	A	-0.1283
179	R	A	-1.5783
180	H	A	-1.9402
181	W	A	-1.0374
182	K	A	-2.1436
183	R	A	-2.0876
184	G	A	0.0460
185	F	A	2.2812
186	I	A	2.6087
187	L	A	1.5685
188	K	A	-1.3619
189	R	A	-2.6329
190	G	A	-2.5627
191	E	A	-2.9021
192	P	A	-1.7234
193	P	A	-1.2981
194	P	A	-1.2234
195	G	A	-1.5640
196	K	A	-2.2992
197	P	A	-1.8065
198	A	A	-1.8168
199	D	A	-2.9250
200	D	A	-2.7707
201	A	A	-0.9123
202	G	A	0.0902
203	L	A	1.9097
204	V	A	1.7297
205	S	A	-0.0074
206	R	A	-1.6387
207	H	A	-1.5267
208	W	A	-0.9885
209	K	A	-2.3193
210	R	A	-1.7513
211	G	A	-0.1565
212	F	A	2.2528
213	I	A	2.4352
214	L	A	1.3501
215	K	A	-1.5699
216	R	A	-2.5989
217	G	A	-2.4665
218	E	A	-3.0069
219	P	A	-1.9852
220	P	A	-1.4077
221	P	A	-1.4505
222	G	A	-1.5999
223	K	A	-2.4003
224	P	A	-1.9347
225	A	A	-1.9627
226	D	A	-3.0026
227	D	A	-2.6173
228	A	A	-0.9609
229	G	A	0.0289
230	L	A	2.0099
231	V	A	2.4228