Project name: 294

Chain sequence(s)	H: EVQLVESGGGLVQAGESLKLSCAASGRPFSTYTMGWFRQAPGKEREIVAASNWSGGSKYYSDSVKGRFTISRDNAKNTVYLQMNSLKPEDTAVYYCATRESGELRIREYEYDYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:06)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:07)

• Minimal score value: -3.2214
• Maximal score value: 1.1263
• Average score: -0.8092
• Total score value: -100.3454

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.5911
2	V	H	0.0000
3	Q	H	-1.4608
4	L	H	0.0000
5	V	H	1.0864
6	E	H	0.2339
7	S	H	-0.3898
8	G	H	-0.8762
9	G	H	-0.5334
11	G	H	0.2362
12	L	H	1.1263
13	V	H	-0.2540
14	Q	H	-1.6127
15	A	H	-1.8988
16	G	H	-1.8964
17	E	H	-2.2288
18	S	H	-1.6424
19	L	H	-0.8052
20	K	H	-1.3661
21	L	H	0.0000
22	S	H	-0.2051
23	C	H	0.0000
24	A	H	-0.1762
25	A	H	0.0000
26	S	H	-1.4475
27	G	H	-2.1584
28	R	H	-2.4298
29	P	H	-1.3080
30	F	H	0.0000
35	S	H	-0.6062
36	T	H	-0.5800
37	Y	H	0.0000
38	T	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.5829
45	A	H	-1.6324
46	P	H	-1.2828
47	G	H	-1.8534
48	K	H	-3.1365
49	E	H	-3.2214
50	R	H	-2.2939
51	E	H	-1.6636
52	I	H	0.0000
53	V	H	0.0000
54	A	H	0.0000
55	A	H	0.0000
56	S	H	0.0000
57	N	H	0.0000
58	W	H	0.3484
59	S	H	-0.1791
62	G	H	-0.7477
63	G	H	-0.8039
64	S	H	-0.9856
65	K	H	-1.3447
66	Y	H	-0.6144
67	Y	H	-0.9082
68	S	H	-1.2698
69	D	H	-2.5290
70	S	H	-1.8621
71	V	H	0.0000
72	K	H	-2.6503
74	G	H	-1.7835
75	R	H	-1.6983
76	F	H	0.0000
77	T	H	-0.9218
78	I	H	0.0000
79	S	H	-0.5702
80	R	H	-0.8196
81	D	H	-1.4512
82	N	H	-1.5462
83	A	H	-1.3519
84	K	H	-2.2232
85	N	H	-1.9166
86	T	H	-0.8663
87	V	H	0.0000
88	Y	H	-0.2724
89	L	H	0.0000
90	Q	H	-0.9831
91	M	H	0.0000
92	N	H	-1.5720
93	S	H	-1.5305
94	L	H	0.0000
95	K	H	-2.4059
96	P	H	-1.8146
97	E	H	-2.2732
98	D	H	0.0000
99	T	H	-0.7585
100	A	H	0.0000
101	V	H	-0.1731
102	Y	H	0.0000
103	Y	H	-0.0506
104	C	H	0.0000
105	A	H	0.0000
106	T	H	0.0000
107	R	H	-1.7060
108	E	H	-2.1157
109	S	H	-1.3669
110	G	H	-0.7411
111	E	H	-1.0644
111A	L	H	-0.6459
111B	R	H	-0.7964
112B	I	H	-0.0065
112A	R	H	-1.3497
112	E	H	-0.9727
113	Y	H	0.2931
114	E	H	-0.7857
115	Y	H	0.0000
116	D	H	-2.0844
117	Y	H	-1.3173
118	W	H	-0.2806
119	G	H	-0.1365
120	Q	H	-0.9411
121	G	H	-0.4155
122	T	H	-0.4902
123	Q	H	-0.6937
124	V	H	0.0000
125	T	H	-0.1829
126	V	H	0.0000
127	S	H	-0.7384
128	S	H	-0.8268