Project name: c19d1f168accdce

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGSFSSYAMGWFRQAPGKGRELVAYISYSGSSTYTKSSRFTISRDNAKRMVYLQMNSLRAEDTAVYYCAASDGIPGRFEYWGQGTQVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:50)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:51)

• Minimal score value: -2.8595
• Maximal score value: 1.2677
• Average score: -0.7376
• Total score value: -84.8214

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.6091
2	V	A	0.0000
3	Q	A	-1.2537
4	L	A	0.0000
5	V	A	1.2677
6	E	A	0.0000
7	S	A	-0.5168
8	G	A	-1.1239
9	G	A	-0.7656
10	G	A	0.1268
11	L	A	1.0158
12	V	A	-0.0375
13	Q	A	-1.3424
14	P	A	-1.7044
15	G	A	-1.5884
16	G	A	-1.1189
17	S	A	-1.5874
18	L	A	-1.1519
19	R	A	-2.3390
20	L	A	0.0000
21	S	A	-0.3671
22	C	A	0.0000
23	A	A	-0.0654
24	A	A	0.0000
25	S	A	-1.2171
26	G	A	-1.5922
27	S	A	-1.4101
28	F	A	0.0000
29	S	A	-0.6916
30	S	A	-0.7567
31	Y	A	0.0000
32	A	A	0.0000
33	M	A	0.0000
34	G	A	0.0000
35	W	A	0.0000
36	F	A	-0.2184
37	R	A	0.0000
38	Q	A	-2.0129
39	A	A	-1.8469
40	P	A	-1.3356
41	G	A	-1.7883
42	K	A	-2.8595
43	G	A	-2.5537
44	R	A	-2.5985
45	E	A	-1.7251
46	L	A	-0.2712
47	V	A	0.0000
48	A	A	0.0000
49	Y	A	0.6445
50	I	A	0.0000
51	S	A	0.1998
52	Y	A	0.6012
53	S	A	-0.0367
54	G	A	-0.2686
55	S	A	-0.2694
56	S	A	-0.0287
57	T	A	0.3133
58	Y	A	0.5193
59	T	A	-0.2664
60	K	A	-1.1976
61	S	A	-0.9328
62	S	A	-0.7451
63	R	A	-1.1770
64	F	A	0.0000
65	T	A	-0.8274
66	I	A	0.0000
67	S	A	-0.4751
68	R	A	-0.9498
69	D	A	-1.7849
70	N	A	-1.7257
71	A	A	-1.5401
72	K	A	-2.5054
73	R	A	-2.2417
74	M	A	-1.0660
75	V	A	0.0000
76	Y	A	-0.6754
77	L	A	0.0000
78	Q	A	-1.7697
79	M	A	0.0000
80	N	A	-2.2123
81	S	A	-1.5815
82	L	A	0.0000
83	R	A	-2.6011
84	A	A	-1.8368
85	E	A	-2.2946
86	D	A	0.0000
87	T	A	-0.9327
88	A	A	0.0000
89	V	A	-0.5933
90	Y	A	0.0000
91	Y	A	-0.0848
92	C	A	0.0000
93	A	A	0.0000
94	A	A	0.0000
95	S	A	0.0000
96	D	A	-2.0924
97	G	A	-0.9069
98	I	A	-0.3639
99	P	A	-0.7918
100	G	A	-1.4056
101	R	A	-2.2777
102	F	A	-1.3828
103	E	A	-1.7128
104	Y	A	-1.0366
105	W	A	0.0935
106	G	A	0.0000
107	Q	A	-0.6596
108	G	A	-0.4481
109	T	A	-0.6569
110	Q	A	-1.0100
111	V	A	0.0000
112	T	A	-0.3299
113	V	A	0.0000
114	S	A	-0.7816
115	S	A	-0.6768