Project name: c1d042636e88312

Chain sequence(s)	H: EVQLVESGGGLVQPGGSLRLSCAASGRTYDAMGWLRQAPGKEREFVAAISGSGDDTYYADSVKGRFTISRDNSKNTLYLQMNSLRPEDTAVYYCATRRGLYYVWDANDYENWGQGTLVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:12)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:14)

• Minimal score value: -3.1464
• Maximal score value: 2.0027
• Average score: -0.6932
• Total score value: -84.5674

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.8087
2	V	H	0.0000
3	Q	H	-1.6971
4	L	H	0.0000
5	V	H	1.1227
6	E	H	0.4510
7	S	H	-0.2386
8	G	H	-0.7673
9	G	H	0.1236
11	G	H	0.8519
12	L	H	1.4802
13	V	H	0.0373
14	Q	H	-1.2818
15	P	H	-1.5889
16	G	H	-1.3002
17	G	H	-0.8836
18	S	H	-1.0760
19	L	H	-0.6647
20	R	H	-1.5882
21	L	H	0.0000
22	S	H	-0.2828
23	C	H	0.0000
24	A	H	-0.3510
25	A	H	-1.2735
26	S	H	-1.5413
27	G	H	-2.2463
28	R	H	-2.2289
29	T	H	-0.8582
36	Y	H	0.7096
37	D	H	0.1939
38	A	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	L	H	0.0000
43	R	H	0.0000
44	Q	H	-1.3830
45	A	H	-1.4026
46	P	H	-1.2520
47	G	H	-1.7714
48	K	H	-2.8876
49	E	H	-3.1464
50	R	H	-2.1926
51	E	H	-1.5370
52	F	H	-0.5445
53	V	H	0.0000
54	A	H	0.0000
55	A	H	0.0000
56	I	H	0.0000
57	S	H	-0.2950
58	G	H	-0.3223
59	S	H	-1.0949
62	G	H	-1.7000
63	D	H	-2.3558
64	D	H	-1.6566
65	T	H	-0.6603
66	Y	H	-0.0392
67	Y	H	-0.7661
68	A	H	-1.2430
69	D	H	-2.5260
70	S	H	-1.8268
71	V	H	0.0000
72	K	H	-2.6512
74	G	H	-1.8167
75	R	H	-1.6114
76	F	H	0.0000
77	T	H	-0.8077
78	I	H	0.0000
79	S	H	-0.8128
80	R	H	-1.3786
81	D	H	-2.1243
82	N	H	-2.5055
83	S	H	-2.1110
84	K	H	-2.9626
85	N	H	-2.9910
86	T	H	-1.4890
87	L	H	0.0000
88	Y	H	-0.4184
89	L	H	0.0000
90	Q	H	-1.1119
91	M	H	0.0000
92	N	H	-1.3244
93	S	H	-1.1648
94	L	H	0.0000
95	R	H	-2.0305
96	P	H	-1.7456
97	E	H	-2.2460
98	D	H	0.0000
99	T	H	-0.3686
100	A	H	0.0000
101	V	H	0.6981
102	Y	H	0.0000
103	Y	H	0.2820
104	C	H	0.0000
105	A	H	0.0000
106	T	H	0.0000
107	R	H	0.0000
108	R	H	-1.2855
109	G	H	0.1683
110	L	H	2.0027
111	Y	H	1.9811
111A	Y	H	1.4312
111B	V	H	0.7549
112B	W	H	0.2454
112A	D	H	-1.2095
112	A	H	-1.5562
113	N	H	-2.2228
114	D	H	-1.9205
115	Y	H	0.0000
116	E	H	-2.1853
117	N	H	0.0000
118	W	H	-0.1686
119	G	H	-0.1345
120	Q	H	-0.6913
121	G	H	0.1209
122	T	H	0.5549
123	L	H	1.5849
124	V	H	0.0000
125	T	H	0.4077
126	V	H	0.0000
127	S	H	-0.7650
128	S	H	-0.6783