Project name: c24be5ce9146a1f

Chain sequence(s)	A: FEKGHFEF; C: FEKGHFEF; B: FEKGHFEF; E: FEKGHFEF; D: FEKGHFEF; G: FEKGHFEF; F: FEKGHFEF; I: FEKGHFEF; H: FEKGHFEF; K: FEKGHFEF; J: FEKGHFEF; M: FEKGHFEF; L: FEKGHFEF; O: FEKGHFEF; N: FEKGHFEF; Q: FEKGHFEF; P: FEKGHFEF; S: FEKGHFEF; R: FEKGHFEF; T: FEKGHFEF
Selected Chain(s)	A,C,B,E,D,G,F,I,H,K,J,M,L,O,N,Q,P,S,R,T
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with all chain(s) selected           (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:05:24)
[INFO]       Main:     Simulation completed successfully.                                          (00:05:28)

• Minimal score value: -2.3494
• Maximal score value: 2.4825
• Average score: 0.152
• Total score value: 24.3252

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	F	A	1.9159
2	E	A	0.2420
3	K	A	-0.4107
4	G	A	0.0000
5	H	A	-0.7035
6	F	A	0.0000
7	E	A	-0.2970
8	F	A	1.3946
1	F	B	2.1635
2	E	B	0.4490
3	K	B	-0.7148
4	G	B	0.0000
5	H	B	-1.0340
6	F	B	-0.5971
7	E	B	-1.0561
8	F	B	0.4888
1	F	C	1.9760
2	E	C	0.4013
3	K	C	-1.2224
4	G	C	0.0000
5	H	C	-1.5889
6	F	C	-0.9897
7	E	C	-1.4197
8	F	C	0.2617
1	F	D	0.9261
2	E	D	-1.5285
3	K	D	-2.3494
4	G	D	-1.6398
5	H	D	-1.9834
6	F	D	-0.9677
7	E	D	-1.2485
8	F	D	1.2333
1	F	E	2.2728
2	E	E	0.8428
3	K	E	-0.2839
4	G	E	0.0000
5	H	E	-0.4874
6	F	E	-0.1411
7	E	E	-0.0620
8	F	E	1.2107
1	F	F	2.1252
2	E	F	0.4627
3	K	F	-0.3377
4	G	F	0.0000
5	H	F	-0.7384
6	F	F	-0.1720
7	E	F	0.3600
8	F	F	1.7430
1	F	G	2.4825
2	E	G	1.1589
3	K	G	-0.3709
4	G	G	0.0000
5	H	G	-0.7581
6	F	G	-0.4186
7	E	G	0.0201
8	F	G	1.3896
1	F	H	2.3485
2	E	H	0.7521
3	K	H	-0.4980
4	G	H	0.0000
5	H	H	-0.9419
6	F	H	-0.4593
7	E	H	0.0091
8	F	H	1.2239
1	F	I	2.3331
2	E	I	0.8319
3	K	I	-0.5357
4	G	I	0.0000
5	H	I	-0.6145
6	F	I	-0.3645
7	E	I	-0.0246
8	F	I	1.4138
1	F	J	2.1595
2	E	J	0.4409
3	K	J	-0.4892
4	G	J	0.0000
5	H	J	-0.6218
6	F	J	-0.3606
7	E	J	0.1425
8	F	J	1.3057
1	F	K	2.2105
2	E	K	0.7563
3	K	K	-0.3777
4	G	K	0.0000
5	H	K	-0.6192
6	F	K	-0.4569
7	E	K	-0.1149
8	F	K	1.1235
1	F	L	2.4194
2	E	L	0.9419
3	K	L	-0.7188
4	G	L	0.0000
5	H	L	-0.5400
6	F	L	-0.2667
7	E	L	0.0892
8	F	L	1.3781
1	F	M	2.2481
2	E	M	0.6496
3	K	M	-0.6539
4	G	M	0.0000
5	H	M	-0.7223
6	F	M	-0.3922
7	E	M	0.0990
8	F	M	1.2390
1	F	N	2.3519
2	E	N	0.7705
3	K	N	-0.7030
4	G	N	0.0000
5	H	N	-0.5844
6	F	N	-0.3292
7	E	N	0.0439
8	F	N	1.2021
1	F	O	2.3700
2	E	O	0.9289
3	K	O	-0.6739
4	G	O	0.0000
5	H	O	-1.1031
6	F	O	-0.6222
7	E	O	-0.0985
8	F	O	1.2412
1	F	P	2.2132
2	E	P	0.3744
3	K	P	-0.8050
4	G	P	0.0000
5	H	P	-0.9822
6	F	P	-0.5962
7	E	P	-0.1926
8	F	P	1.1060
1	F	Q	2.2342
2	E	Q	0.2738
3	K	Q	-0.7681
4	G	Q	0.0000
5	H	Q	-0.6341
6	F	Q	-0.5490
7	E	Q	0.1554
8	F	Q	1.3042
1	F	R	2.2844
2	E	R	0.7506
3	K	R	-0.5765
4	G	R	0.0000
5	H	R	-0.7323
6	F	R	-0.4888
7	E	R	-0.1191
8	F	R	1.2441
1	F	S	1.2678
2	E	S	-1.0221
3	K	S	-1.7526
4	G	S	-1.2437
5	H	S	-1.5542
6	F	S	-0.7716
7	E	S	-0.9195
8	F	S	1.3424
1	F	T	2.1001
2	E	T	0.7214
3	K	T	-0.7783
4	G	T	0.0000
5	H	T	-1.2269
6	F	T	-0.6987
7	E	T	-0.6673
8	F	T	0.8957