Project name: Halo7

Chain sequence(s)	A: GIGTGFPFDPHYVEVLGERMHYVDVGPRDGTPVLFLHGNPTSSYVWRNIIPHVAPTHRCIAPDLIGMGKSDKPDLGYFFDDHVRFMDAFIEALGLEEVVLVIHDWGSALGFHWAKRNPERVKGIAFMEFIIRPIPTWDDEWPEFARETFQAFRTTDVGRKLIIIDQNVFIEGTLPMMGVVRPLTEVEMDHYREPFLNPVDREPLWRFPNELPIAGEEPANIVALVEEYMDDWLLHQQSPVPKLLFWGTPGVLIPPAEAARLAKSLPNNCKAVDIGPGLNLLQEDNPDLIGSEIARWLSTLEI
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:43)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:45)

• Minimal score value: -3.1809
• Maximal score value: 0.9188
• Average score: -0.6907
• Total score value: -202.3842

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
3	G	A	-0.1826
4	I	A	-0.0440
5	G	A	-0.1294
6	T	A	-0.1493
7	G	A	-0.1553
8	F	A	-0.1680
9	P	A	-0.4993
10	F	A	-0.7429
11	D	A	-1.8009
12	P	A	-1.3158
13	H	A	-0.8893
14	Y	A	-0.8334
15	V	A	-0.9288
16	E	A	-2.3060
17	V	A	0.0000
18	L	A	-0.2211
19	G	A	-1.0729
20	E	A	-1.9318
21	R	A	-2.8672
22	M	A	0.0000
23	H	A	0.0000
24	Y	A	-0.5330
25	V	A	0.0000
26	D	A	-0.6294
27	V	A	-0.5010
28	G	A	-1.0760
29	P	A	-1.8667
30	R	A	-2.9978
31	D	A	-3.0601
32	G	A	-1.7976
33	T	A	0.0000
34	P	A	0.0000
35	V	A	0.0000
36	L	A	0.0000
37	F	A	0.0000
38	L	A	0.0000
39	H	A	0.0000
40	G	A	0.0000
41	N	A	0.0000
42	P	A	0.0000
43	T	A	0.0000
44	S	A	-0.3394
45	S	A	0.0000
46	Y	A	0.0000
47	V	A	0.0000
48	W	A	0.0000
49	R	A	0.0000
50	N	A	-0.6487
51	I	A	0.0000
52	I	A	0.0000
53	P	A	-0.6786
54	H	A	-0.9718
55	V	A	0.0000
56	A	A	-0.4216
57	P	A	-0.4871
58	T	A	-0.8930
59	H	A	-1.1449
60	R	A	-1.3536
61	C	A	0.0000
62	I	A	0.0000
63	A	A	0.0000
64	P	A	0.0000
65	D	A	0.0000
66	L	A	0.0000
67	I	A	0.0000
68	G	A	0.0000
69	M	A	0.0000
70	G	A	-1.5505
71	K	A	-2.4916
72	S	A	0.0000
73	D	A	-2.7325
74	K	A	-2.1347
75	P	A	-1.8314
76	D	A	-1.8960
77	L	A	-0.6734
78	G	A	-0.4337
79	Y	A	0.0000
80	F	A	0.4417
81	F	A	0.0000
82	D	A	-1.8959
83	D	A	-1.2434
84	H	A	0.0000
85	V	A	-1.4127
86	R	A	-2.2835
87	F	A	0.0000
88	M	A	0.0000
89	D	A	-1.3978
90	A	A	-1.2472
91	F	A	0.0000
92	I	A	0.0000
93	E	A	-2.0972
94	A	A	-1.0262
95	L	A	-0.9002
96	G	A	-1.4726
97	L	A	0.0000
98	E	A	-2.7718
99	E	A	-2.1420
100	V	A	0.0000
101	V	A	0.0000
102	L	A	0.0000
103	V	A	0.0000
104	I	A	0.0000
105	H	A	0.0000
106	D	A	0.0000
107	W	A	0.0000
108	G	A	0.0000
109	S	A	0.0000
110	A	A	0.0000
111	L	A	0.0000
112	G	A	0.0000
113	F	A	0.0000
114	H	A	-0.7842
115	W	A	0.0000
116	A	A	0.0000
117	K	A	-1.8854
118	R	A	-1.6877
119	N	A	-1.6872
120	P	A	-1.8403
121	E	A	-2.7007
122	R	A	-2.3189
123	V	A	0.0000
124	K	A	-1.1198
125	G	A	0.0000
126	I	A	0.0000
127	A	A	0.0000
128	F	A	0.0000
129	M	A	0.0000
130	E	A	0.0000
131	F	A	0.0000
132	I	A	0.0000
133	R	A	0.0000
134	P	A	-0.7891
135	I	A	0.0000
136	P	A	-1.0360
137	T	A	-1.2387
138	W	A	-1.7724
139	D	A	-2.6432
140	E	A	-2.1893
141	W	A	0.0000
142	P	A	-1.1619
143	E	A	-1.8030
144	F	A	0.6890
145	A	A	0.0000
146	R	A	-1.8835
147	E	A	-2.2035
148	T	A	-1.0402
149	F	A	0.0000
150	Q	A	-1.3809
151	A	A	-1.1432
152	F	A	0.0000
153	R	A	-0.7131
154	T	A	-0.9017
155	T	A	-1.2044
156	D	A	-1.9224
157	V	A	-0.8823
158	G	A	0.0000
159	R	A	-2.0239
160	K	A	-2.5375
161	L	A	-1.3658
162	I	A	0.0000
163	I	A	-1.3319
164	D	A	-2.6041
165	Q	A	-2.4677
166	N	A	0.0000
167	V	A	-0.9875
168	F	A	0.0000
169	I	A	0.0000
170	E	A	-1.4482
171	G	A	-0.7742
172	T	A	-0.2824
173	L	A	0.0000
174	P	A	-0.1115
175	M	A	0.4919
176	G	A	0.0000
177	V	A	0.0000
178	V	A	0.9188
179	R	A	0.1163
180	P	A	-0.2355
181	L	A	-0.0197
182	T	A	-0.6828
183	E	A	-1.6991
184	V	A	-0.4034
185	E	A	0.0000
186	M	A	0.0000
187	D	A	-2.3711
188	H	A	-1.8590
189	Y	A	0.0000
190	R	A	-1.8761
191	E	A	-2.5789
192	P	A	-1.7291
193	F	A	0.0000
194	L	A	0.2784
195	N	A	-0.5592
196	P	A	-0.2907
197	V	A	0.7602
198	D	A	-0.1539
199	R	A	0.0000
200	E	A	-0.3044
201	P	A	0.0000
202	L	A	0.0000
203	W	A	0.0000
204	R	A	-0.1846
205	F	A	0.0000
206	P	A	0.0000
207	N	A	-0.4920
208	E	A	0.0000
209	L	A	0.0000
210	P	A	0.0000
211	I	A	0.0000
212	A	A	-1.1268
213	G	A	-1.4683
214	E	A	-2.2522
215	P	A	-1.5749
216	A	A	-1.2682
217	N	A	-1.6388
218	I	A	0.0000
219	V	A	-1.3299
220	A	A	-1.4131
221	L	A	-1.2764
222	V	A	0.0000
223	E	A	-2.9145
224	E	A	-3.0887
225	Y	A	0.0000
226	M	A	0.0000
227	D	A	-3.1809
228	W	A	-2.1993
229	L	A	0.0000
230	H	A	-1.5796
231	Q	A	-1.9148
232	S	A	-1.3095
233	P	A	-0.9967
234	V	A	0.0000
235	P	A	-0.9573
236	K	A	0.0000
237	L	A	0.0000
238	L	A	0.0000
239	F	A	0.0000
240	W	A	-0.4995
241	G	A	0.0000
242	T	A	-0.3792
243	P	A	-0.1383
244	G	A	0.0000
245	V	A	0.1012
246	L	A	0.0000
247	I	A	0.0000
248	P	A	-0.3398
249	P	A	-0.6131
250	A	A	-0.5367
251	E	A	-0.8627
252	A	A	0.0000
253	A	A	-1.3509
254	R	A	-1.8558
255	L	A	0.0000
256	A	A	-1.7158
257	K	A	-2.4288
258	S	A	-1.6128
259	L	A	0.0000
260	P	A	-1.5762
261	N	A	-1.9835
262	C	A	-1.4606
263	K	A	-1.5328
264	A	A	-1.0269
265	V	A	0.0000
266	D	A	-1.6233
267	I	A	0.0000
268	G	A	-0.8118
269	P	A	-0.4285
270	G	A	0.0000
271	L	A	0.3429
272	N	A	0.1865
273	L	A	0.0000
274	L	A	0.0000
275	Q	A	0.0000
276	E	A	0.0000
277	D	A	-0.3377
278	N	A	-1.0517
279	P	A	0.0000
280	D	A	-1.8117
281	L	A	-0.9421
282	I	A	0.0000
283	G	A	0.0000
284	S	A	-0.9943
285	E	A	-0.8752
286	I	A	0.0000
287	A	A	-0.7782
288	R	A	-1.2254
289	W	A	0.0000
290	L	A	0.0000
291	S	A	-0.7327
292	T	A	-0.5991
293	L	A	-0.7453
294	E	A	-1.4547
295	I	A	-0.3163