Project name: c57f611504a66db

Chain sequence(s)	H: EVQLLESGGGLVQPGGSLRLSCAMSGHFFNLYIMAWFRQAPGKEREFVAGVSTSGRTSLYADSVKGRFTISRDNSKTTGYLQMNSLKSEDTAVYYCAARSSASELWVPSGDEYYAWWGQGTTVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:07)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:08)

• Minimal score value: -3.747
• Maximal score value: 1.4374
• Average score: -0.6907
• Total score value: -87.7227

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.3203
2	V	H	0.0000
3	Q	H	-1.3349
4	L	H	0.0000
5	L	H	0.8819
6	E	H	0.0033
7	S	H	-0.4580
8	G	H	-1.0924
9	G	H	-0.4954
10	G	H	0.2254
11	L	H	1.1231
12	V	H	0.0000
13	Q	H	-1.4729
14	P	H	-1.7377
15	G	H	-1.4745
16	G	H	-0.9861
17	S	H	-1.2755
18	L	H	-0.9329
19	R	H	-2.1229
20	L	H	0.0000
21	S	H	-0.4570
22	C	H	0.0000
23	A	H	-0.0865
24	M	H	0.0000
25	S	H	-0.7830
26	G	H	-1.2938
27	H	H	-0.7030
28	F	H	0.8795
29	F	H	0.0000
30	N	H	-0.6058
31	L	H	0.7278
32	Y	H	0.5017
33	I	H	0.0000
34	M	H	0.0000
35	A	H	0.0000
36	W	H	0.0000
37	F	H	0.0000
38	R	H	-1.5678
39	Q	H	-2.2192
40	A	H	-1.9612
41	P	H	-1.4188
42	G	H	-1.9738
43	K	H	-3.4724
44	E	H	-3.7470
45	R	H	-3.2623
46	E	H	-3.2187
47	F	H	0.0000
48	V	H	0.0000
49	A	H	0.0000
50	G	H	0.0000
51	V	H	0.0000
52	S	H	0.0000
53	T	H	-0.4510
54	S	H	-0.9292
55	G	H	-1.6965
56	R	H	-1.9433
57	T	H	-0.6284
58	S	H	-0.2876
59	L	H	0.1396
60	Y	H	-0.7282
61	A	H	-1.5407
62	D	H	-2.4942
63	S	H	-1.8429
64	V	H	0.0000
65	K	H	-2.6115
66	G	H	-1.8029
67	R	H	-1.5526
68	F	H	0.0000
69	T	H	-0.8133
70	I	H	0.0000
71	S	H	-0.7904
72	R	H	-1.4615
73	D	H	-1.9423
74	N	H	-2.1642
75	S	H	-1.9410
76	K	H	-2.3707
77	T	H	-1.6925
78	T	H	0.0000
79	G	H	0.0000
80	Y	H	-0.6364
81	L	H	0.0000
82	Q	H	-1.2224
83	M	H	0.0000
84	N	H	-1.4091
85	S	H	-1.2718
86	L	H	0.0000
87	K	H	-2.4224
88	S	H	-1.9755
89	E	H	-2.2465
90	D	H	0.0000
91	T	H	-0.7497
92	A	H	0.0000
93	V	H	-0.0257
94	Y	H	0.0000
95	Y	H	-0.2844
96	C	H	0.0000
97	A	H	0.0000
98	A	H	0.0000
99	R	H	-0.0332
100	S	H	0.2088
101	S	H	0.2876
102	A	H	0.1684
103	S	H	-0.0375
104	E	H	0.3547
105	L	H	1.4374
106	W	H	1.4215
107	V	H	0.0000
108	P	H	0.0000
109	S	H	-0.5982
110	G	H	-1.3199
111	D	H	-2.0294
112	E	H	-1.9280
113	Y	H	-0.4233
114	Y	H	0.0000
115	A	H	-0.0621
116	W	H	0.1271
117	W	H	0.0312
118	G	H	-0.2627
119	Q	H	-0.9596
120	G	H	-0.4114
121	T	H	-0.2657
122	T	H	0.0747
123	V	H	0.0000
124	T	H	-0.0913
125	V	H	0.0000
126	S	H	-0.5652
127	S	H	-0.9263