Project name: ca326164a0c6362

Chain sequence(s)	A: DPRLPLTAKQKYSMLASWKGISRAMEKTGICMFIKLFEENEELLHLFEKFRELRTKEAIVSSAELAEHATQVMHTLDEGIKGLADMDSFFTYVRHVGGTHRQVPGFKAENFMKIEQPFLEAAKTTLGERYTPNIENIYKLTIRFILENLVKGYAENGTTQT
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:40)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:41)

• Minimal score value: -4.4237
• Maximal score value: 0.6606
• Average score: -1.3481
• Total score value: -217.0516

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	D	A	-2.6877
2	P	A	-1.6026
3	R	A	-2.0486
4	L	A	0.0000
5	P	A	-0.6602
6	L	A	0.0000
7	T	A	-0.8861
8	A	A	-0.8685
9	K	A	-1.4435
10	Q	A	-0.9637
11	K	A	-0.3560
12	Y	A	0.6606
13	S	A	-0.0035
14	M	A	0.0000
15	L	A	-0.0961
16	A	A	-0.0361
17	S	A	-0.6060
18	W	A	0.0000
19	K	A	-2.1734
20	G	A	-1.7314
21	I	A	0.0000
22	S	A	-2.1958
23	R	A	-2.7720
24	A	A	-2.1634
25	M	A	0.0000
26	E	A	-3.2370
27	K	A	-2.4828
28	T	A	0.0000
29	G	A	0.0000
30	I	A	-0.9070
31	C	A	-0.6492
32	M	A	0.0000
33	F	A	0.0000
34	I	A	0.0000
35	K	A	-2.1107
36	L	A	0.0000
37	F	A	0.0000
38	E	A	-4.0959
39	E	A	-3.8900
40	N	A	-3.2824
41	E	A	-4.4237
42	E	A	-3.5853
43	L	A	0.0000
44	L	A	0.0000
45	H	A	-2.8969
46	L	A	0.0000
47	F	A	-2.1615
48	E	A	-3.4404
49	K	A	-3.4831
50	F	A	0.0000
51	R	A	-4.2886
52	E	A	-3.6513
53	L	A	-2.8793
54	R	A	-3.6948
55	T	A	-2.5186
56	K	A	-2.8215
57	E	A	-2.5001
58	A	A	-1.6892
59	I	A	0.0000
60	V	A	-0.3826
61	S	A	-0.5144
62	S	A	0.0000
63	A	A	-0.7833
64	E	A	-1.8808
65	L	A	0.0000
66	A	A	-1.8531
67	E	A	-2.7450
68	H	A	-2.0917
69	A	A	0.0000
70	T	A	-2.3276
71	Q	A	-2.1160
72	V	A	-1.1459
73	M	A	0.0000
74	H	A	-1.7811
75	T	A	-1.2311
76	L	A	0.0000
77	D	A	-1.9137
78	E	A	-2.3796
79	G	A	0.0000
80	I	A	0.0000
81	K	A	-2.5276
82	G	A	-2.0832
83	L	A	0.0000
84	A	A	-1.4961
85	D	A	-2.8257
86	M	A	0.0000
87	D	A	-2.5437
88	S	A	-1.7553
89	F	A	0.0000
90	F	A	-1.2837
91	T	A	-0.8824
92	Y	A	-0.8106
93	V	A	0.0000
94	R	A	-1.7295
95	H	A	-1.4778
96	V	A	-0.6204
97	G	A	0.0000
98	G	A	-1.8328
99	T	A	-1.1698
100	H	A	-1.4632
101	R	A	-2.4659
102	Q	A	-1.7796
103	V	A	-0.9276
104	P	A	-1.0313
105	G	A	-1.2280
106	F	A	-1.6246
107	K	A	-2.4543
108	A	A	-2.1981
109	E	A	-2.5587
110	N	A	-1.6812
111	F	A	0.0000
112	M	A	-1.4024
113	K	A	-1.8427
114	I	A	-1.0936
115	E	A	-1.4436
116	Q	A	-2.0464
117	P	A	0.0000
118	F	A	0.0000
119	L	A	0.0000
120	E	A	-1.3643
121	A	A	0.0000
122	A	A	0.0000
123	K	A	-2.2474
124	T	A	-1.3369
125	T	A	-1.5242
126	L	A	0.0000
127	G	A	-2.1978
128	E	A	-3.0473
129	R	A	-3.1724
130	Y	A	-2.3618
131	T	A	-1.9404
132	P	A	-1.4733
133	N	A	-2.1402
134	I	A	-1.6817
135	E	A	-1.9733
136	N	A	-2.0414
137	I	A	0.0000
138	Y	A	0.0000
139	K	A	-1.7275
140	L	A	-0.6159
141	T	A	0.0000
142	I	A	0.0000
143	R	A	-1.7942
144	F	A	-0.8477
145	I	A	0.0000
146	L	A	0.0000
147	E	A	-2.2179
148	N	A	0.0000
149	L	A	0.0000
150	V	A	-1.5775
151	K	A	-2.1961
152	G	A	-1.9973
153	Y	A	-1.9399
154	A	A	-1.8293
155	E	A	-2.7476
156	N	A	-2.4018
157	G	A	-1.7797
158	T	A	-0.9807
159	T	A	-1.0199
160	Q	A	-1.3771
161	T	A	-0.7501