Project name: cb91a35b79d6471

Chain sequence(s)	H: AWVDQTPRTATKETGESLTINCVLKGSGFELSDTGWYRTKLGSTNEQSISIGGRYVETVNKGSKSFSLRISDLRVEDSGTYKCVAYYKVGDGGKGKIRTVEGEKGAGTALTVKAA
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:42)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:42)

• Minimal score value: -3.1647
• Maximal score value: 1.1113
• Average score: -0.893
• Total score value: -102.6977

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	A	H	-0.1811
2	W	H	0.2007
3	V	H	0.0000
4	D	H	-1.3246
5	Q	H	0.0000
6	T	H	-1.1439
7	P	H	-1.2700
8	R	H	-2.0339
9	T	H	-1.0078
10	A	H	-0.5670
11	T	H	-0.6750
12	K	H	-1.5345
13	E	H	-2.2790
14	T	H	-2.1235
15	G	H	-2.2512
16	E	H	-2.5180
17	S	H	-1.9761
18	L	H	0.0000
19	T	H	-0.8868
20	I	H	0.0000
21	N	H	-1.0562
22	C	H	0.0000
23	V	H	-0.6762
24	L	H	0.0000
25	K	H	-0.7917
26	G	H	-0.7306
27	S	H	-0.8049
28	G	H	-1.0264
29	F	H	-0.9060
30	E	H	-2.0325
31	L	H	0.0000
32	S	H	-1.5148
33	D	H	-1.9289
34	T	H	-1.1351
35	G	H	-0.4669
36	W	H	0.0000
37	Y	H	-0.8633
38	R	H	-1.0521
39	T	H	-1.1969
40	K	H	-1.0073
41	L	H	0.6048
42	G	H	-0.0935
43	S	H	-0.6268
44	T	H	-1.0126
45	N	H	-2.0289
46	E	H	-2.1208
47	Q	H	-1.9485
48	S	H	-0.7948
49	I	H	-0.0362
50	S	H	0.4537
51	I	H	1.1113
52	G	H	0.2955
53	G	H	-0.2860
54	R	H	-0.7792
55	Y	H	0.0000
56	V	H	0.9233
57	E	H	0.3123
58	T	H	-0.2871
59	V	H	-0.7538
60	N	H	-1.9625
61	K	H	-3.0128
62	G	H	-1.9966
63	S	H	-1.5638
64	K	H	-1.9778
65	S	H	-1.1670
66	F	H	0.0000
67	S	H	-0.5349
68	L	H	0.0000
69	R	H	-1.4295
70	I	H	0.0000
71	S	H	-1.7155
72	D	H	-2.4882
73	L	H	0.0000
74	R	H	-2.2188
75	V	H	-0.6551
76	E	H	-1.6263
77	D	H	0.0000
78	S	H	0.0000
79	G	H	0.0000
80	T	H	-0.3228
81	Y	H	0.0000
82	K	H	-0.7729
83	C	H	0.0000
84	V	H	0.0000
85	A	H	0.0000
86	Y	H	-0.8941
87	Y	H	0.0000
88	K	H	-1.1862
89	V	H	-0.9379
90	G	H	-2.3009
91	D	H	-3.1450
92	G	H	-2.1575
93	G	H	-2.2605
94	K	H	-3.1647
95	G	H	-2.6308
96	K	H	-2.4284
97	I	H	-0.8561
98	R	H	-1.9914
99	T	H	-0.4857
100	V	H	0.4562
101	E	H	-0.6751
102	G	H	-1.1396
103	E	H	-1.1900
104	K	H	-1.4720
105	G	H	0.0000
106	A	H	-0.7860
107	G	H	0.0000
108	T	H	0.0000
109	A	H	-0.4079
110	L	H	0.0000
111	T	H	-0.5288
112	V	H	0.0000
113	K	H	-1.7729
114	A	H	-0.8138
115	A	H	-0.6553