Project name: 296

Chain sequence(s)	H: EVQLVESGGGLVQAGGSLRLSCAASGRTFSGYDMGWFRQAPGKEREFVAQISRHNSNTYYADAVKGRFTISRDNAKNTVSLQMNSLKPEDTAVYYCAIGSLFPSSRERDYDYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:59)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:00)

• Minimal score value: -3.111
• Maximal score value: 2.267
• Average score: -0.7668
• Total score value: -94.3105

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-2.6996
2	V	H	0.0000
3	Q	H	-1.7057
4	L	H	0.0000
5	V	H	0.6907
6	E	H	0.0000
7	S	H	-0.6007
8	G	H	-1.0759
9	G	H	-0.5660
11	G	H	0.2510
12	L	H	1.1439
13	V	H	0.0581
14	Q	H	-1.2255
15	A	H	-1.4192
16	G	H	-1.3033
17	G	H	-0.8711
18	S	H	-1.0596
19	L	H	-0.6696
20	R	H	-1.6667
21	L	H	0.0000
22	S	H	-0.3938
23	C	H	0.0000
24	A	H	-0.1764
25	A	H	0.0000
26	S	H	-1.2841
27	G	H	-1.9732
28	R	H	-2.3108
29	T	H	-1.3412
30	F	H	0.0000
35	S	H	-1.2540
36	G	H	-0.5971
37	Y	H	0.0000
38	D	H	0.0000
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	F	H	0.0000
43	R	H	0.0000
44	Q	H	-1.6332
45	A	H	-1.6416
46	P	H	-1.1940
47	G	H	-1.7308
48	K	H	-2.9296
49	E	H	-3.1110
50	R	H	-2.1248
51	E	H	-1.7543
52	F	H	-0.6904
53	V	H	0.0000
54	A	H	0.0000
55	Q	H	0.0000
56	I	H	0.0000
57	S	H	0.0000
58	R	H	-1.1345
59	H	H	-1.9532
62	N	H	-1.8271
63	S	H	-1.4364
64	N	H	-1.6023
65	T	H	-0.3968
66	Y	H	0.4096
67	Y	H	-0.1984
68	A	H	-0.8741
69	D	H	-2.0067
70	A	H	-1.3192
71	V	H	0.0000
72	K	H	-1.6480
74	G	H	-1.3626
75	R	H	-1.2317
76	F	H	0.0000
77	T	H	-0.5316
78	I	H	0.0000
79	S	H	-0.6570
80	R	H	0.0000
81	D	H	-2.0287
82	N	H	-2.5053
83	A	H	-1.7050
84	K	H	-2.4691
85	N	H	-2.0935
86	T	H	-1.1118
87	V	H	0.0000
88	S	H	0.0000
89	L	H	0.0000
90	Q	H	-0.9648
91	M	H	0.0000
92	N	H	-1.2598
93	S	H	-1.1692
94	L	H	0.0000
95	K	H	-2.2502
96	P	H	-1.8148
97	E	H	-2.2715
98	D	H	0.0000
99	T	H	-0.7663
100	A	H	0.0000
101	V	H	-0.2211
102	Y	H	0.0000
103	Y	H	-0.0847
104	C	H	0.0000
105	A	H	0.0000
106	I	H	0.0000
107	G	H	0.0000
108	S	H	0.1393
109	L	H	1.8621
110	F	H	2.2670
111	P	H	0.6641
111A	S	H	-0.4198
112B	S	H	-1.2079
112A	R	H	-2.9214
112	E	H	-2.7063
113	R	H	-3.1037
114	D	H	-1.9651
115	Y	H	0.0000
116	D	H	-1.8438
117	Y	H	-0.8790
118	W	H	-0.2273
119	G	H	-0.2388
120	Q	H	-1.0008
121	G	H	-0.4587
122	T	H	-0.5242
123	Q	H	-0.6364
124	V	H	0.0000
125	T	H	-0.1612
126	V	H	0.0000
127	S	H	-0.7767
128	S	H	-0.8266