Project name: cdb5d4de9ad4da3

Chain sequence(s)	H: EVQLLESGGGLVQAGGSLRLSCAASGFTFSNYAMGWYRQAPGKERELVSAISSGSSTYYADSVKGRFTISRDNSKNTLYLQMNSLRPEDTAVYYCAPLAEPDSGSGSYYPTGYWGQGTQVTVSS
Selected Chain(s)	H
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with H chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:00:45)
[INFO]       Main:     Simulation completed successfully.                                          (00:00:45)

• Minimal score value: -3.2902
• Maximal score value: 1.2104
• Average score: -0.6388
• Total score value: -79.2135

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	H	-1.9843
2	V	H	-1.0650
3	Q	H	-1.0627
4	L	H	0.0000
5	L	H	0.6538
6	E	H	-0.0395
7	S	H	-0.6290
8	G	H	-0.9947
9	G	H	-0.5642
11	G	H	0.2210
12	L	H	1.1568
13	V	H	0.0774
14	Q	H	-1.2243
15	A	H	-1.5685
16	G	H	-1.2932
17	G	H	-0.8484
18	S	H	-0.9660
19	L	H	-0.4943
20	R	H	-1.2622
21	L	H	0.0000
22	S	H	-0.2807
23	C	H	0.0000
24	A	H	-0.1850
25	A	H	0.0000
26	S	H	-0.8300
27	G	H	-1.1925
28	F	H	-0.5818
29	T	H	-0.4678
30	F	H	0.0000
35	S	H	-1.2892
36	N	H	-1.2591
37	Y	H	-0.2634
38	A	H	-0.3242
39	M	H	0.0000
40	G	H	0.0000
41	W	H	0.0000
42	Y	H	0.2033
43	R	H	0.0000
44	Q	H	-1.6613
45	A	H	-1.7897
46	P	H	-1.3628
47	G	H	-1.9145
48	K	H	-3.2060
49	E	H	-3.2902
50	R	H	-2.1579
51	E	H	-1.3323
52	L	H	0.0555
53	V	H	0.0000
54	S	H	0.0000
55	A	H	0.4993
56	I	H	0.0000
57	S	H	-0.3413
58	S	H	-0.7802
59	G	H	-0.8454
63	S	H	-0.5472
64	S	H	-0.2716
65	T	H	0.2855
66	Y	H	0.7352
67	Y	H	-0.3434
68	A	H	-1.0435
69	D	H	-2.3763
70	S	H	-1.7616
71	V	H	0.0000
72	K	H	-2.4379
74	G	H	-1.7124
75	R	H	-1.3995
76	F	H	0.0000
77	T	H	-0.5527
78	I	H	0.0000
79	S	H	-0.3692
80	R	H	-1.0813
81	D	H	-1.7003
82	N	H	-2.1834
83	S	H	-1.7735
84	K	H	-2.5070
85	N	H	-1.9257
86	T	H	-1.1080
87	L	H	0.0000
88	Y	H	-0.2865
89	L	H	0.0000
90	Q	H	-0.7843
91	M	H	0.0000
92	N	H	-1.1771
93	S	H	-1.1151
94	L	H	0.0000
95	R	H	-2.2541
96	P	H	-1.8388
97	E	H	-2.2980
98	D	H	0.0000
99	T	H	-0.7843
100	A	H	0.0000
101	V	H	-0.2122
102	Y	H	0.0000
103	Y	H	0.0944
104	C	H	0.0000
105	A	H	0.0000
106	P	H	0.0000
107	L	H	0.3159
108	A	H	-0.3682
109	E	H	-1.0669
110	P	H	-1.5301
111	D	H	-2.1829
111A	S	H	-1.2701
111B	G	H	-0.7253
112C	S	H	-0.7026
112B	G	H	-1.0188
112A	S	H	0.0142
112	Y	H	1.2104
113	Y	H	1.0891
114	P	H	0.3461
115	T	H	0.4982
116	G	H	0.4994
117	Y	H	0.5141
118	W	H	0.7001
119	G	H	0.0000
120	Q	H	-0.8600
121	G	H	-0.4195
122	T	H	-0.6011
123	Q	H	-0.7089
124	V	H	0.0000
125	T	H	-0.1275
126	V	H	0.0000
127	S	H	-0.7596
128	S	H	-0.8452