Project name: cf8690f3c5d82bb

Chain sequence(s)	A: MNLTKILPTFAAVVVLSACAKDAPEMTKSSAQIAEMQTLPTITDKTVVYSCNKQTVTAVYQFENQEPVAAMVSVGDGIIAKDFTRDKSQNDFTSFVSGDYVWNVDSGLTLDKFDSVVPVNLIQKGKSSDNIIVKNCDVNVKATKKANL
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:01)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:01)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:01)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:01)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:01)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:02:36)
[INFO]       Main:     Simulation completed successfully.                                          (00:02:37)

• Minimal score value: -3.0426
• Maximal score value: 3.9049
• Average score: -0.6382
• Total score value: -94.4583

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	M	A	0.7641
2	N	A	-0.2375
3	L	A	0.9215
4	T	A	0.0550
5	K	A	-0.1571
6	I	A	1.9946
7	L	A	2.1954
8	P	A	1.4555
9	T	A	1.4145
10	F	A	2.2508
11	A	A	1.5846
12	A	A	2.0432
13	V	A	3.5459
14	V	A	3.9049
15	V	A	3.8361
16	L	A	2.9906
17	S	A	1.3867
18	A	A	0.8700
19	C	A	0.4060
20	A	A	-0.7713
21	K	A	-2.4759
22	D	A	-2.9319
23	A	A	-1.6860
24	P	A	-1.6732
25	E	A	-1.9202
26	M	A	-0.5472
27	T	A	-1.0492
28	K	A	-1.7625
29	S	A	-0.9534
30	S	A	-0.5238
31	A	A	-0.6279
32	Q	A	-0.9037
33	I	A	0.7684
34	A	A	-0.1131
35	E	A	-1.3240
36	M	A	0.1177
37	Q	A	-0.6672
38	T	A	0.0747
39	L	A	1.3112
40	P	A	0.3415
41	T	A	0.3382
42	I	A	0.7377
43	T	A	-0.8162
44	D	A	-1.7616
45	K	A	-1.7379
46	T	A	-1.1152
47	V	A	0.0000
48	V	A	-0.6720
49	Y	A	0.0000
50	S	A	-1.7678
51	C	A	0.0000
52	N	A	-3.0426
53	K	A	-2.8252
54	Q	A	-2.2069
55	T	A	-1.4906
56	V	A	0.0000
57	T	A	0.0254
58	A	A	0.0000
59	V	A	-0.4011
60	Y	A	0.0000
61	Q	A	-1.1284
62	F	A	0.0000
63	E	A	-1.2253
64	N	A	-1.5975
65	Q	A	-2.5738
66	E	A	-2.3173
67	P	A	0.0000
68	V	A	-0.5395
69	A	A	-0.9673
70	A	A	0.0000
71	M	A	-0.6337
72	V	A	0.0000
73	S	A	0.0000
74	V	A	0.0067
75	G	A	-1.1327
76	D	A	-1.6428
77	G	A	-0.2480
78	I	A	0.9902
79	I	A	0.4824
80	A	A	-0.5174
81	K	A	-2.0322
82	D	A	-2.5011
83	F	A	0.0000
84	T	A	-0.9084
85	R	A	-1.1395
86	D	A	-1.5504
87	K	A	-2.4298
88	S	A	-1.9277
89	Q	A	-2.1958
90	N	A	-2.6700
91	D	A	-2.5590
92	F	A	-1.5431
93	T	A	0.0000
94	S	A	0.0000
95	F	A	0.0000
96	V	A	-0.0245
97	S	A	-0.9279
98	G	A	-1.2150
99	D	A	-1.8123
100	Y	A	-0.5504
101	V	A	0.0907
102	W	A	0.0000
103	N	A	0.0000
104	V	A	0.0000
105	D	A	-1.0483
106	S	A	-1.2390
107	G	A	-1.3872
108	L	A	0.0000
109	T	A	-2.0607
110	L	A	-2.4183
111	D	A	-2.8832
112	K	A	-2.4192
113	F	A	-1.4413
114	D	A	-1.5145
115	S	A	-1.1864
116	V	A	0.0000
117	V	A	-0.4307
118	P	A	0.0000
119	V	A	-0.0032
120	N	A	0.3014
121	L	A	0.0000
122	I	A	-0.0208
123	Q	A	-1.3214
124	K	A	-2.9082
125	G	A	-2.8880
126	K	A	-2.4973
127	S	A	-1.7959
128	S	A	-1.9084
129	D	A	-2.5601
130	N	A	-1.2251
131	I	A	1.0351
132	I	A	0.9988
133	V	A	0.0000
134	K	A	-1.1564
135	N	A	-2.3350
136	C	A	-2.0159
137	D	A	-1.8825
138	V	A	-0.6890
139	N	A	-0.9894
140	V	A	-0.4446
141	K	A	-1.9721
142	A	A	-1.5917
143	T	A	0.0000
144	K	A	-2.6242
145	K	A	-2.3260
146	A	A	-1.1471
147	N	A	-1.0863
148	L	A	0.3926