Project name: 19_x4e7_i20e6_i14e7_x11e6

Chain sequence(s)	A: GPGPGLLCHEQLSDSEEENDGPGPGQSTHVDIRTLEDLLMGPGPGTPTLHEYMLDLQPETGPGPGLQDIVLHLEPQNEIPGPGPGVYDFAFRDLAAYRFHNIAGHYAAYCYSLYGTTLAAYKTVLELTEVAAYYRAHYNIVTFAAYTLQDIVLHLAAYLLMGTLGIVAAYLPARRAEPQAAYAEKLRHLNEKRRFHNGPGPGLDKKQRFHNIRGRWTGPGPGNPAEKLRHLNEKRRFGPGPGSKISEYRHYCYSLYGGPGPG
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:03:33)
[INFO]       Main:     Simulation completed successfully.                                          (00:03:34)

• Minimal score value: -4.6744
• Maximal score value: 3.7194
• Average score: -0.3925
• Total score value: -102.8409

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	G	A	-0.6882
2	P	A	-0.7632
3	G	A	-0.7800
4	P	A	-0.4640
5	G	A	0.3740
6	L	A	2.1182
7	L	A	2.3741
8	C	A	1.0528
9	H	A	-1.4499
10	E	A	-2.4642
11	Q	A	-1.6796
12	L	A	0.0281
13	S	A	-0.5070
14	D	A	-2.2672
15	S	A	-2.5064
16	E	A	-3.8361
17	E	A	-4.3312
18	E	A	-4.2928
19	N	A	-3.8279
20	D	A	-3.3746
21	G	A	-2.1128
22	P	A	-1.3278
23	G	A	-1.2887
24	P	A	-1.1052
25	G	A	-1.3713
26	Q	A	-1.8011
27	S	A	-1.0559
28	T	A	-0.7847
29	H	A	-0.6425
30	V	A	0.6825
31	D	A	-0.8044
32	I	A	0.7142
33	R	A	-1.3748
34	T	A	-0.6148
35	L	A	0.6370
36	E	A	-1.1500
37	D	A	-1.0698
38	L	A	1.4755
39	L	A	1.9465
40	M	A	1.3279
41	G	A	0.4361
42	P	A	-0.3842
43	G	A	-0.9432
44	P	A	-0.8513
45	G	A	-0.8520
46	T	A	-0.3541
47	P	A	-0.1553
48	T	A	-0.0199
49	L	A	0.6354
50	H	A	-0.6890
51	E	A	-0.7648
52	Y	A	1.0814
53	M	A	1.5026
54	L	A	1.6299
55	D	A	-0.1554
56	L	A	0.3759
57	Q	A	-1.3715
58	P	A	-1.6062
59	E	A	-2.2380
60	T	A	-1.5078
61	G	A	-1.2225
62	P	A	-1.0098
63	G	A	-0.7785
64	P	A	-0.5388
65	G	A	-0.5084
66	L	A	0.4058
67	Q	A	-0.7012
68	D	A	-0.3580
69	I	A	2.1635
70	V	A	2.7505
71	L	A	2.4691
72	H	A	0.7212
73	L	A	0.5903
74	E	A	-1.7245
75	P	A	-1.9641
76	Q	A	-2.3877
77	N	A	-2.5579
78	E	A	-1.8769
79	I	A	0.4030
80	P	A	-0.2468
81	G	A	-0.5555
82	P	A	-0.4302
83	G	A	-0.5511
84	P	A	-0.2539
85	G	A	0.4920
86	V	A	2.3730
87	Y	A	2.2772
88	D	A	0.8433
89	F	A	1.8919
90	A	A	1.4628
91	F	A	1.7730
92	R	A	-0.8166
93	D	A	-0.7939
94	L	A	0.9490
95	A	A	-0.0284
96	A	A	-0.0949
97	Y	A	0.3686
98	R	A	-0.8871
99	F	A	0.5762
100	H	A	-0.5037
101	N	A	-1.0553
102	I	A	0.6640
103	A	A	0.3587
104	G	A	-0.5858
105	H	A	-0.1682
106	Y	A	1.3143
107	A	A	0.8149
108	A	A	1.1443
109	Y	A	1.8235
110	C	A	1.8422
111	Y	A	2.2897
112	S	A	1.7188
113	L	A	2.3481
114	Y	A	2.0503
115	G	A	0.9159
116	T	A	0.6989
117	T	A	0.5215
118	L	A	1.2414
119	A	A	1.2708
120	A	A	0.8386
121	Y	A	1.4750
122	K	A	-0.0250
123	T	A	0.3959
124	V	A	1.7894
125	L	A	0.5898
126	E	A	-0.8499
127	L	A	1.1551
128	T	A	0.1244
129	E	A	-1.1991
130	V	A	0.3117
131	A	A	0.0085
132	A	A	-0.7034
133	Y	A	-0.0320
134	Y	A	-0.1142
135	R	A	-1.1620
136	A	A	-0.6811
137	H	A	-0.9750
138	Y	A	-0.0378
139	N	A	0.0382
140	I	A	1.9683
141	V	A	2.4642
142	T	A	1.5898
143	F	A	1.4048
144	A	A	1.4796
145	A	A	1.4377
146	Y	A	1.6115
147	T	A	1.6125
148	L	A	2.0615
149	Q	A	0.8435
150	D	A	0.5138
151	I	A	2.4133
152	V	A	3.0130
153	L	A	2.4995
154	H	A	1.8345
155	L	A	3.0488
156	A	A	2.8456
157	A	A	2.7851
158	Y	A	3.5382
159	L	A	3.6516
160	L	A	3.7194
161	M	A	3.4439
162	G	A	2.5451
163	T	A	2.7928
164	L	A	3.4670
165	G	A	2.3330
166	I	A	3.3041
167	V	A	3.0174
168	A	A	2.0062
169	A	A	1.7562
170	Y	A	1.8882
171	L	A	0.8906
172	P	A	-0.7009
173	A	A	-1.1460
174	R	A	-2.8834
175	R	A	-3.2450
176	A	A	-2.4122
177	E	A	-3.2149
178	P	A	-2.2840
179	Q	A	-2.3987
180	A	A	-1.6138
181	A	A	-1.3332
182	Y	A	-0.6993
183	A	A	-1.5518
184	E	A	-2.9374
185	K	A	-2.8604
186	L	A	-2.0456
187	R	A	-3.9831
188	H	A	-4.0722
189	L	A	-3.2672
190	N	A	-4.0322
191	E	A	-4.6414
192	K	A	-4.3144
193	R	A	-4.6744
194	R	A	-3.9819
195	F	A	-1.6241
196	H	A	-2.6163
197	N	A	-2.7474
198	G	A	-1.6989
199	P	A	-1.0786
200	G	A	-0.9671
201	P	A	-0.5904
202	G	A	-0.5637
203	L	A	-0.5469
204	D	A	-2.6467
205	K	A	-3.3484
206	K	A	-3.4520
207	Q	A	-3.3276
208	R	A	-2.6567
209	F	A	-0.6021
210	H	A	-1.6110
211	N	A	-1.7477
212	I	A	0.0776
213	R	A	-1.6187
214	G	A	-1.8133
215	R	A	-1.7731
216	W	A	-0.1251
217	T	A	-0.5045
218	G	A	-0.5531
219	P	A	-0.6202
220	G	A	-0.9834
221	P	A	-1.1300
222	G	A	-1.5978
223	N	A	-2.3421
224	P	A	-2.0049
225	A	A	-2.1549
226	E	A	-3.4779
227	K	A	-3.1035
228	L	A	-1.7870
229	R	A	-3.6573
230	H	A	-3.6687
231	L	A	-2.8283
232	N	A	-3.5279
233	E	A	-4.2417
234	K	A	-4.0971
235	R	A	-3.9230
236	R	A	-3.1563
237	F	A	-0.7769
238	G	A	-1.0979
239	P	A	-0.8040
240	G	A	-0.7396
241	P	A	-1.0686
242	G	A	-1.0325
243	S	A	-1.0138
244	K	A	-1.2116
245	I	A	0.6628
246	S	A	-0.4528
247	E	A	-1.5146
248	Y	A	-0.4001
249	R	A	-1.7625
250	H	A	-0.7599
251	Y	A	1.1882
252	C	A	1.6886
253	Y	A	2.3267
254	S	A	1.7879
255	L	A	2.3265
256	Y	A	1.8447
257	G	A	0.1858
258	G	A	-0.4454
259	P	A	-0.9349
260	G	A	-0.9800
261	P	A	-0.8179
262	G	A	-0.7270