Project name: ozomab

Chain sequence(s)	A: EVQLVESGGGLVQPGGSLRLSCAASGFTFSDYWMYWVRQAPGKGLEWVSEINTNGLITKYPDSVKGRFTISRDNAKNTLYLQMNSLRPEDTAVYYCARSPSGFNRGQGTLVTVSS
Selected Chain(s)	A
Distance of aggregation	10 Å
FoldX usage	Yes
Dynamic mode	No
Automated mutations	No

Simulation log

[INFO]       Logger:   Verbosity set to: 2 - [INFO]                                                (00:00:00)
[WARNING]    runJob:   Working directory already exists (possibly overwriting previous results -ow 
                       to prevent this behavior)                                                   (00:00:00)
[INFO]       runJob:   Starting aggrescan3d job on: input.pdb with A chain(s) selected             (00:00:00)
[INFO]       runJob:   Creating pdb object from: input.pdb                                         (00:00:00)
[INFO]       FoldX:    Starting FoldX energy minimalization                                        (00:00:00)
[INFO]       Analysis: Starting Aggrescan3D on folded.pdb                                          (00:01:29)
[INFO]       Main:     Simulation completed successfully.                                          (00:01:30)

• Minimal score value: -2.9024
• Maximal score value: 1.7636
• Average score: -0.6113
• Total score value: -70.2991

The table below lists A3D score for protein residues. Residues with A3D score > 0.0000 are marked by yellow rows.

residue index	residue name	chain	Aggrescan3D score	mutation
1	E	A	-2.0645
2	V	A	-1.4604
3	Q	A	-1.6097
4	L	A	0.0000
5	V	A	0.9582
6	E	A	0.0000
7	S	A	-0.1089
8	G	A	-0.7160
9	G	A	0.1477
10	G	A	0.6568
11	L	A	1.3446
12	V	A	0.0000
13	Q	A	-1.4001
14	P	A	-1.6155
15	G	A	-1.4026
16	G	A	-1.0244
17	S	A	-1.4573
18	L	A	-1.0133
19	R	A	-2.1084
20	L	A	0.0000
21	S	A	-0.3343
22	C	A	0.0000
23	A	A	-0.0671
24	A	A	0.0000
25	S	A	-0.9905
26	G	A	-1.2244
27	F	A	-0.6623
28	T	A	-0.6104
29	F	A	0.0000
30	S	A	-1.3014
31	D	A	-1.6728
32	Y	A	-0.2437
33	W	A	0.2480
34	M	A	0.0000
35	Y	A	-0.1905
36	W	A	0.0000
37	V	A	0.0000
38	R	A	0.0000
39	Q	A	-0.8220
40	A	A	-1.1764
41	P	A	-1.1474
42	G	A	-1.5263
43	K	A	-2.3178
44	G	A	-1.4371
45	L	A	-0.5056
46	E	A	-0.6959
47	W	A	0.0037
48	V	A	0.0000
49	S	A	0.0000
50	E	A	-0.2912
51	I	A	0.0000
52	N	A	0.0000
53	T	A	-0.5220
54	N	A	-0.9533
55	G	A	0.2085
56	L	A	1.7636
57	I	A	1.6702
58	T	A	0.3808
59	K	A	-1.5021
60	Y	A	-1.6473
61	P	A	-1.7183
62	D	A	-2.7231
63	S	A	-1.8002
64	V	A	0.0000
65	K	A	-2.9024
66	G	A	-1.9088
67	R	A	-1.8603
68	F	A	0.0000
69	T	A	-1.2138
70	I	A	0.0000
71	S	A	-0.2229
72	R	A	-0.9490
73	D	A	-1.5901
74	N	A	-1.9974
75	A	A	-1.3339
76	K	A	-2.2451
77	N	A	-1.6492
78	T	A	-0.9163
79	L	A	0.0000
80	Y	A	-0.5261
81	L	A	0.0000
82	Q	A	-1.5425
83	M	A	0.0000
84	N	A	-2.0732
85	S	A	-1.4321
86	L	A	0.0000
87	R	A	-2.2853
88	P	A	-1.9311
89	E	A	-2.3272
90	D	A	0.0000
91	T	A	-0.4956
92	A	A	0.0000
93	V	A	0.7016
94	Y	A	0.0000
95	Y	A	-0.0915
96	C	A	0.0000
97	A	A	0.0000
98	R	A	-0.2932
99	S	A	0.0381
100	P	A	-0.1239
101	S	A	0.0671
102	G	A	0.0000
103	F	A	0.9537
104	N	A	-0.8797
105	R	A	-1.3689
106	G	A	-0.9273
107	Q	A	-1.3134
108	G	A	-0.1584
109	T	A	0.6278
110	L	A	1.6845
111	V	A	0.0000
112	T	A	0.2814
113	V	A	0.0000
114	S	A	-0.8472
115	S	A	-0.5651